GENERIC NAME OF MEDICINAL PRODUCT:

(A) Procaine Benzyl Penicillin for Injection B.P. 0.6+0.2 MIU

QUALITATIVE AND QUANTITATIVE COMPOSITION:

A. Procaine Benzyl Penicillin for Injection B.P. 0.6+0.2 MIU
a) Each vial contains:
Procaine Penicillin BP……..6,00,000 IU
Benzyl Penicillin Sodium BP
(As sodium)………………………2,00,000IU
b) Sterile Water for Injection BP ….…………… 20ml

THERAPEUTIC INDICATION:

Procaine benzylpenicillin is a local anaesthetic and antibiotic combination for intramuscular injection to treat a variety of bacterial infections while reducing pain from a deep intramuscular injection. Procaine benzylpenicillin (INN), also known as procaine G penicillin, is an injectable antibiotic.

DIRECTION OF USE:

The powder to be reconstituted with 20ml of Sterile Water for Injections BP.
FOR IM USE ONLY
The reconstituted solution should be use immediately after preparation. The prepared solution should be used only, if it is clear.

CAUTION & WARNING:

CAUTION: If any foreign particle is visible in the vial after dissolving the contents, please do not use the solution.
FLIP-OFF SEAL IS PROVIDED FOR TAMPER EVIDENCE.
WARNING: Not to be sold by retail without the prescription of Registered Medical Practitioner.

STORAGE & DOSAGE:

STORAGE: Store below 25°C. Protect from Light. Do not freeze.
Keep medicine out of reach of children.
Reconstituted solution should be use immediately after preparation.
Any unused reconstitution portion must be discarded.
Read enclosed leaflet before use.
DOSAGE: As directed by Physician.

Procaine Benzyl Penicillin for Injection B.P. 0.6+0.2 MIU Technical Specification:

Product Name:Procaine Benzyl Penicillin for Injection B.P.
Brand Name:Generics
Strength:0.6+0.2 MIU
Dosage Form:Dry Powder Injection (Sterile)
Packing:Vial + WFI in Tray
Route of Administration:For I.M. use
Pack Insert/Leaflet:PIL (Patient Information Leaflet), SmPC (Summary Product Characteristics)
Regulatory Documents:COA, MOA, COPP, FSC, Stability Studies, GMP, CTD Dossier
Therapeutic use:β-lactam Antibiotic, Anti-bacterial & Penicillin
Indication: Procaine benzylpenicillin is a local anesthetic and antibiotic combination for intramuscular injection to treat a variety of bacterial infections while reducing pain from a deep intramuscular injection. Procaine benzylpenicillin (INN), also known as procaine G penicillin, is an injectable antibiotic.
Storage:Store below 25°C. Protect from Light. Do not freeze.

GENERIC NAME OF MEDICINAL PRODUCT:

  • Procaine Benzyl Penicillin for Injection B.P. 0.6+0.2 MIU 

QUALITATIVE AND QUANTITATIVE COMPOSITION:

  • Procaine Benzyl Penicillin for Injection B.P. 0.6+0.2 MIU
    a) Each vial contains:
    Procaine Penicillin BP……..6,00,000 IU
    Benzyl Penicillin Sodium BP
    (As sodium)………………………2,00,000IU
    b) Sterile Water for Injection BP ….…………… 20ml

THERAPEUTIC INDICATION:

Procaine benzylpenicillin is a local anesthetic and antibiotic combination for intramuscular injection to treat a variety of bacterial infections while reducing pain from a deep intramuscular injection. Procaine benzylpenicillin (INN), also known as procaine G penicillin, is an injectable antibiotic.

DIRECTION OF USE:

The powder is to be reconstituted with 20ml of Sterile Water for Injections BP.
FOR I.M. USE ONLY
The reconstituted solution should be used immediately after preparation. The prepared solution should be used only if it is clear.

CAUTION & WARNING:

CAUTION: If any foreign particle is visible in the vial after dissolving the contents, please do not use the solution.

FLIP-OFF SEAL IS PROVIDED FOR TAMPER EVIDENCE.

WARNING: Not to be sold by retail without the prescription of a Registered Medical Practitioner.
[Note: BenzylPenicillin = PenicillinG]

STORAGE & DOSAGE:

STORAGE: Store below 25°C. Protect from Light. Do not freeze.

Keep the medicine out of reach of children.
The reconstituted solution should be used immediately after preparation.
Any unused reconstitution portion must be discarded.

Read the enclosed leaflet before use.

DOSAGE: As directed by the Physician.

Why Taj Pharmaceuticals?

Experience the unparalleled excellence of Taj Pharma’s Procaine Benzyl Penicillin for Injection BP. With a legacy of delivering top-tier pharmaceutical solutions, Taj Pharma is the foremost choice for healthcare professionals and patients alike. Our unwavering commitment to quality sets us apart. We adhere to the most stringent international standards, ensuring that every vial of Procaine Benzyl Penicillin for Injection BP meets and exceeds your expectations. You can trust us to provide pharmaceuticals that prioritize safety and efficacy, giving you peace of mind. Taj Pharma’s supply chain reliability is second to none. We understand the importance of consistent access to essential medications. With Taj Pharma, you can count on a steady and dependable supply, eliminating disruptions and ensuring that your patients receive the care they deserve. Make Taj Pharma your partner in healthcare. Discover why our Procaine Benzyl Penicillin for Injection BP is the preferred choice of healthcare professionals worldwide. Join the countless others who have chosen quality, reliability, and trust by choosing Taj Pharma.

What is Procaine Benzyl Penicillin for Injection BP and its use?

Procaine Benzyl Penicillin for Injection BP is a pharmaceutical product that combines two important components: procaine and benzylpenicillin. Let’s delve into each component and its uses in detail:

  • Procaine: Procaine is a local anesthetic. It belongs to the class of drugs known as amino ester local anesthetics. Its primary role in this combination medication is to alleviate the discomfort and pain associated with the injection of benzylpenicillin. When procaine is administered alongside benzylpenicillin, it numbs the surrounding tissue, making the injection less painful for the patient. This enhances patient comfort and compliance during the administration of the antibiotic.
  • Benzyl penicillin (Penicillin G): Benzyl penicillin is a well-known antibiotic that falls under the category of penicillins. It is renowned for its efficacy against a wide range of bacterial infections

Uses:

  • Bacterial Infections: Benzyl penicillin is highly effective against various bacterial infections, especially those caused by Gram-positive bacteria. It can be used to treat conditions such as skin and soft tissue infections, respiratory tract infections (e.g., pneumonia and bronchitis), and bone and joint infections.
  • Syphilis: Benzyl penicillin is a crucial antibiotic in the treatment of syphilis, a sexually transmitted infection caused by the bacterium Treponema pallidum.
  • Rheumatic Fever and Rheumatic Heart Disease: This antibiotic may be employed in the prevention and treatment of infections associated with rheumatic fever and rheumatic heart disease. These conditions can develop as a result of untreated streptococcal infections.
  • Bacterial Endocarditis Prophylaxis: In some cases, benzylpenicillin is used prophylactic ally to prevent bacterial endocarditis in individuals with certain heart conditions before dental or surgical procedures.

It’s crucial to use Procaine Benzyl Penicillin for Injection BP only under the supervision and prescription of a qualified healthcare provider. The specific dosage, frequency, and duration of treatment will depend on the type and severity of the bacterial infection being treated. Furthermore, individuals with known allergies to penicillin or related antibiotics should not use this medication unless suitable alternatives are available, as it can potentially trigger severe allergic reactions. Always seek professional medical advice for personalized guidance regarding the use of this medication.

How does Procaine Benzyl Penicillin for Injection BP work?

Procaine Benzyl Penicillin for Injection BP combines two key components, procaine and benzylpenicillin, to effectively treat bacterial infections. To understand how it works, it’s essential to break down the actions of each component:

  • Procaine:
    Procaine is a local anesthetic. Its primary role in this combination medication is to provide pain relief and reduce discomfort at the injection site.
    When Procaine Benzyl Penicillin is injected into the patient, procaine quickly numbs the surrounding tissues. This numbing effect is achieved by blocking the transmission of pain signals in the nerves located near the injection site.
    By reducing pain and discomfort during the injection, procaine improves patient tolerance and compliance with the treatment.
  • Benzyl penicillin (Penicillin G):
    Benzyl penicillin is an antibiotic from the penicillin class. It works by interfering with the synthesis of bacterial cell walls, which are crucial for the structural integrity of bacterial cells.
    Bacterial cells have a peptidogly can layer in their cell walls, which provides stability and protection. Benzyl penicillin inhibits the action of an enzyme called transpeptidase, which is involved in cross linking the peptidogly can chains.
    When transpeptidase activity is inhibited, bacterial cell walls become weak and structurally unstable. As a result, bacteria are unable to maintain their cell shape and integrity.
    This disruption in cell wall synthesis ultimately leads to the lysis (breakdown) of bacterial cells, preventing them from reproducing and spreading. It also makes bacteria more vulnerable to the body’s immune system, which can then eliminate the infection.

Benefits of Procaine Benzyl Penicillin for Injection BP:

  • Effective Antibacterial Treatment: Procaine Benzyl Penicillin is highly effective against a wide range of bacterial infections, including those caused by Gram-positive bacteria. It is particularly useful in treating conditions like skin infections, respiratory tract infections, syphilis, and bone and joint infections.
  • Proven Track Record: Benzyl penicillin, the antibiotic component of this medication, has a long history of successful use in the treatment of bacterial infections. It is considered a first-line treatment for many bacterial illnesses.
  • Pain Reduction: The inclusion of procaine, a local anesthetic, in the injection helps reduce pain and discomfort during the administration of the medication, making it more tolerable for patients.
  • Prevention of Complications: In certain cases, such as in the treatment of streptococcal infections, Procaine Benzyl Penicillin can help prevent the development of serious complications like rheumatic fever and rheumatic heart disease.

Side Effects of Procaine Benzyl Penicillin for Injection BP:

It’s important to note that while Procaine Benzyl Penicillin can be highly effective, it may also cause side effects in some individuals. Common side effects include:

  • Allergic Reactions: Allergic reactions to penicillin antibiotics, including benzylpenicillin, can range from mild rashes to severe anaphylaxis. These reactions can be life-threatening in some cases.
  • Gastrointestinal Disturbances: Some people may experience digestive issues such as nausea, vomiting, diarrhea, or abdominal pain.
  • Pain or Swelling at the Injection Site: While procaine helps reduce pain during the injection, some individuals may still experience mild pain, redness, or swelling at the injection site.
  • Superinfections: Prolonged use of antibiotics can lead to the development of secondary infections, such as fungal or bacterial overgrowth. This is because antibiotics can disrupt the normal balance of microorganisms in the body.
  • Neurological Side Effects: In rare cases, high doses of procaine can lead to neurological side effects, such as nervousness, confusion, and seizures.
  • Kidney or Liver Problems: Although uncommon, some individuals may experience kidney or liver issues as a result of using this medication.
  • Blood Disorders: Procaine Benzyl Penicillin can affect the blood, leading to issues like low platelet counts (thrombocytopenia) or anemia.
  • Clostridium difficile Infection: Like many antibiotics, Procaine Benzyl Penicillin can disrupt the balance of bacteria in the gut, potentially leading to Clostridium difficile infection, which causes severe diarrhea.

It’s crucial to use Procaine Benzyl Penicillin under the supervision of a healthcare professional who can assess its appropriateness for your condition, monitor for side effects, and make any necessary adjustments to your treatment. If you experience any severe or unusual side effects, seek immediate medical attention. Additionally, inform your healthcare provider of any known allergies to antibiotics, especially penicillins, before starting this medication.

Frequently Asked Questions about Procaine Benzyl Penicillin for Injection BP:

Certainly! Here are some frequently asked questions (FAQs) about Procaine Benzyl Penicillin for Injection BP:

  1. What is Procaine Benzyl Penicillin for Injection BP?

Procaine Benzyl Penicillin for Injection BP is a pharmaceutical product that combines procaine (a local anesthetic) with benzylpenicillin (an antibiotic). It is used to treat bacterial infections while reducing pain and discomfort during the injection.

  1. How does it work?

Procaine numbs the injection site, making it less painful, while benzylpenicillin targets and weakens bacterial cell walls, ultimately leading to bacterial cell death.

  1. What types of infections does it treat?

Procaine Benzyl Penicillin is effective against various bacterial infections, including skin and soft tissue infections, respiratory tract infections, syphilis, and bone and joint infections.

  1. How is it administered?

It is typically administered as an intramuscular injection by a healthcare professional. The procaine component helps reduce the pain associated with the injection.

  1. Are there any side effects?

Common side effects include allergic reactions, gastrointestinal disturbances, pain or swelling at the injection site, and the potential for secondary infections. Rare side effects may include neurological symptoms and blood disorders.

  1. Can anyone use Procaine Benzyl Penicillin for Injection BP?

It should be used under the supervision of a healthcare provider. Individuals with known allergies to penicillin or related antibiotics should not use this medication without suitable alternatives.

  1. How long should I take it?

The duration of treatment and dosage will depend on the type and severity of the bacterial infection. Always follow your healthcare provider’s instructions.

  1. Is it safe during pregnancy and breastfeeding?

It should be used during pregnancy or breastfeeding only if the potential benefits outweigh the risks. Consult with a healthcare provider for guidance in these situations.

  1. Can I drink alcohol while using this medication?

It’s generally advisable to avoid alcohol while on antibiotics to prevent potential interactions and minimize strain on the liver.

  1. What should I do if I miss a dose?

Contact your healthcare provider if you miss a dose. They will provide guidance on whether you need to take the missed dose or adjust your treatment.

  1. Is it available over the counter (OTC)?

No, Procaine Benzyl Penicillin for Injection BP is a prescription medication and is not available OTC.

  1. Can I stop taking it if my symptoms improve?

It’s essential to complete the full course of antibiotics as prescribed by your healthcare provider, even if your symptoms improve. Stopping early could allow the infection to return or develop antibiotic resistance.

  1. What should I do if I experience severe side effects or an allergic reaction?

Seek immediate medical attention if you experience severe side effects or symptoms of an allergic reaction, such as difficulty breathing, swelling, or a severe rash.

Always consult with your healthcare provider for personalized information and guidance regarding the use of Procaine Benzyl Penicillin for Injection BP and any concerns you may have.

As Procaine Benzyl Penicillin for Injection BP Exporters; We can cater to export business queries from the following geographies. We are exporting our Procaine Benzyl Penicillin for Injection BP product in the Following Countries-

Russia and CIS Countries: Azerbaijan, Armenia, Belarus, Georgia, Kazakhstan, Kyrgyzstan, Moldova, Russia, Tajikistan, Turkmenistan, Uzbekistan and Ukraine

GCC/ Middle East Countries: Saudi Arabia, Yemen, Oman, Bahrain, UAE, Lebanon, Jordan, and Iraq.

African Countries: Nigeria, Tanzania, Sudan, Zambia, Benin, Angola, Liberia

Southeast Asia: Cambodia, Indonesia, Laos, Malaysia, Myanmar, Philippines, Singapore, Thailand, Vietnam, Brunei Darussalam

Other Asian Countries: Nepal, Myanmar, Malaysia, Cambodia, Bhutan, Sri Lanka, Mauritius

Procaine Benzyl Penicillin for Injection BP Regulatory Documents:

  • Certificate of Analysis (COA)
  • Method of Analysis (MOA)
  • Stability Data (Accelerated stability / Long-term stability / Zone 4b)
  • CTD Dossier / ACTD Dossiers / eCTD Dossiers
  • Certificate of Pharmaceuticals Product (COPP)
  • Free Sale Certificate (FSC)
Contact the most reliable manufacturer of Procaine Benzyl Penicillin for Injection BP, Taj Pharmaceuticals Limited, to get bulk quantities at a reasonable price.

To Place Orders:

Direct line: +91 8448 444 095 / WhatsApp +91 74 0000 9975 / 74 0000 9976
E-Mail: info@tajpharma.com 
Toll free: 1-800-222-434 / Toll free: 1-800-222-825
General EPA BX: +91 22 2637 4592 / +91 22 2637 4593
Fax No: +91 22 2634 1274