GENERIC NAME OF THE MEDICINAL PRODUCT:

A. Doxycycline for Injection USP 100mg
B. Doxycycline for Injection USP 200mg

QUALITATIVE AND QUANTITATIVE COMPOSITION:

Doxycycline for Injection USP 100mg
a) Each Vial Contains:
Doxycycline Hyclate (Sterile) USP
Equivalent to Doxycycline ….…….100 mg
b) Ascorbic Acid Injection USP
Each 5ml contains:
Ascorbic Acid USP……………….500mg
Water for Injection USP…………. q.s
c) Sterile Water for Injection USP……10ml


2) Doxycycline Hydrochloride USP 200mg
a) Each Vial Contains:
Doxycycline Hyclate (Sterile) USP
Equivalent to Doxycycline ….…….200 mg
b) Ascorbic Acid Injection USP
Each 5ml contains:
Ascorbic acid USP……………….500mg
Water for Injection USP…………. q.s
c) Sterile Water for Injection USP……10ml

THERAPEUTIC INDICATIONS:

Doxycycline is in a class of medications called tetracycline antibiotics. It works to treat infections by preventing the growth and spread of bacteria. It works to treat acne by killing the bacteria that infects pores and decreasing a certain natural oily substance that causes acne

DIRECTION OF USE:

MUST BE FURTHER DILUTED AFTER RECONSTITUTION
Reconstituted solutions must be stored and used as prescribed.
They must be used within the time period as described.
Protect solution from direct sunlight during infusion.
1. Each 100mg of Doxycycline (i.e. withdraw entire solution from the 100 mg vial) is further diluted with 100 to 1000 mL of the intravenous solutions listed below:
A. 0.9% Sodium Chloride Injection USP
B. 5% Dextrose Injection BP
This will result in desired concentrations of 0.1 to 1 mg/mL concentrations lower than 0.1 mg/mL or higher than 1mg/mL are not recommended.

CAUTION & WARNING:

CAUTION: If any foreign particle is visible in the vial after dissolving the contents, please do not use the solution.
Reconstituted solution should be used immediately after preparation.
FLIP-OFF SEAL IS PROVIDED FOR TAMPER EVIDENCE
Retain in carton until time of use.
Reconstituted solutions must be stored and used as prescribed.
They must be used within the time period as described.
Protect solution from direct sunlight during infusion.
WARNING: To be sold by retail on the prescribed of a registered medical partitioner only.

STORAGE & DOSAGE:

Storage: Store in cool, dry & dark place. Store at 20°C to 25°C. Protect from light.
Vial stopper do not contain natural rubber latex.
Keep all medicines out of reach of children.
Dosage: As directed by Physician.

Doxycycline for Injection USP 100mg Technical Specification:

Product Name:Doxycycline for Injection USP 100mg
Brand Name:Doxitaj
Strength:100mg, 200mg
Dosage Form:Lyophilized
Dry Powder Injection (Sterile) *Preservative Free
Packing:1 Vial + 1 Ampule + WFI Tray
Route of Administration:For I.V. use only
Pack Insert/Leaflet:PIL (Patient Information Leaflet), SmPC (Summary Product Characteristics)
Regulatory Documents:COA, MOA, COPP, FSC, Stability Studies, GMP, CTD Dossier
Therapeutic use:Broad-Spectrum Antibiotic (tetracycline) & Anti-bacterial
Indication: Doxycycline is in a class of medications called tetracycline antibiotics. It works to treat infections by preventing the growth and spread of bacteria.
Storage:Store in cool, dry & dark place. Store at 20°C to 25°C.  Protect from light.

GENERIC NAME OF MEDICINAL PRODUCT:

  • Doxycycline for Injection USP 100mg

QUALITATIVE AND QUANTITATIVE COMPOSITION:

  •  Doxycycline for Injection USP 100mg
    a)
    Each Vial Contains:
    Doxycycline Hyclate (Sterile) USP
    Equivalent to Doxycycline ….…….100 mg
    b) Ascorbic Acid Injection USP
    Each 5ml contains:
    Ascorbic Acid USP……………….500mg
    Water for Injection USP…………. q.s
    c) Sterile Water for Injection USP……10ml

THERAPEUTIC INDICATIONS:

Doxycycline is in a class of medications called tetracycline antibiotics. It works to treat infections by preventing the growth and spread of bacteria. It works to treat acne by killing the bacteria that infects pores and decreasing a certain natural oily substance that causes acne

DIRECTION OF USE:

MUST BE FURTHER DILUTED AFTER RECONSTITUTION

Reconstituted solutions must be stored and used as prescribed. They must be used within the time period as described. Protect solution from direct sunlight during infusion.

  • Each 100mg of Doxycycline (i.e. withdraw entire solution from the 100 mg vial) is further diluted with 100 to 1000 mL of the intravenous solutions listed below:
  1. 9% Sodium Chloride Injection USP
  2. 5% Dextrose Injection BP

This will result in desired concentrations of 0.1 to 1 mg/mL concentrations lower than 0.1 mg/mL or higher than 1mg/mL are not recommended.

CAUTION & Warning:

CAUTION: If any foreign particle is visible in the vial after dissolving the contents, please do not use the solution.

Reconstituted solution should be used immediately after preparation.
FLIP-OFF SEAL IS PROVIDED FOR TAMPER EVIDENCE

Retain in carton until time of use.
Reconstituted solutions must be stored and used as prescribed.

They must be used within the time period as described.
Protect solution from direct sunlight during infusion.

Warning: To be sold by retail on the prescribed of a registered medical partitioner only.

STORAGE & DOSAGE:

Storage: Store in cool, dry & dark place. Store at 20°C to 25°C.  Protect from light.

Vial stopper do not contain natural rubber latex.

Keep all medicines out of reach of children.

Dosage: As directed by Physician.

Why Taj Pharmaceuticals?

Taj Pharmaceuticals is a renowned pharmaceutical company known for its commitment to excellence in the field of pharmaceuticals, and this commitment extends to their Doxycycline For Injection . With a strong legacy of quality production, Taj Pharmaceuticals has established itself as a trusted provider of high-quality medications that meet stringent industry standards. This dedication to quality is particularly evident in their Doxycycline For Injection , which are valued for their effectiveness in treating a wide range of bacterial infections. Doxycycline is a versatile antibiotic known for its efficacy against various bacterial infections, making it a valuable tool in the medical field. Taj Pharmaceuticals ensures the reliability and effectiveness of their Doxycycline For Injection , making them a dependable choice for patients and healthcare providers alike. Taj Pharmaceuticals places patient well-being at the core of their healthcare initiatives. Their patient-centric approach is reflected in the quality and effectiveness of their medications, emphasizing the importance of providing accessible healthcare solutions that enhance the lives of individuals. With a vast distribution network, Taj Pharmaceuticals ensures that their medications, including Doxycycline For Injection , are readily available to patients and healthcare providers worldwide. This global accessibility is especially critical in addressing the global prevalence of infectious diseases, where timely and effective treatment is essential. Affordability is another key aspect of Taj Pharmaceuticals’ philosophy. They aim to provide cost-effective healthcare solutions without compromising on quality. Their Doxycycline For Injection offer an effective antibiotic treatment option that is also budget-friendly, catering to individuals seeking economical choices for their healthcare needs. Taj Pharmaceuticals specializes in antibiotic treatments and possesses extensive knowledge and experience in this therapeutic area. Their expertise ensures that individuals receive tailored antibiotic solutions for their specific medical conditions, contributing to better treatment outcomes. In addition to their commitment to quality and expertise, Taj Pharmaceuticals offers a comprehensive product line, including various antibiotics. This diversity allows healthcare providers to choose the most suitable treatment options for their patients, further demonstrating Taj Pharmaceuticals’ commitment to delivering effective healthcare solutions. When it comes to addressing bacterial infections and promoting health, Taj Pharmaceuticals is a trusted choice for reliable and accessible medications.

What is Doxycycline For Injection and its use?

Doxycycline For Injection are a medication that contains the active ingredient doxycycline, which is a versatile antibiotic used to treat a wide range of bacterial infections. Here are some of the primary uses of Doxycycline For Injection :

  • Respiratory Tract Infections: Doxycycline is commonly prescribed to treat respiratory tract infections such as bronchitis, sinusitis, and pneumonia caused by susceptible bacteria. It helps clear the infection and alleviate symptoms like cough, fever, and congestion.
  • Skin and Soft Tissue Infections: Doxycycline is effective against skin and soft tissue infections like cellulitis, abscesses, and wound infections. It helps to control bacterial growth, reduce inflammation, and promote healing.
  • Acne: Doxycycline is used in the treatment of moderate to severe acne. It works by reducing inflammation associated with acne lesions and inhibiting the growth of acne-causing bacteria. It is often prescribed as a longer-term treatment for acne.
  • Sexually Transmitted Infections: Doxycycline is used to treat certain sexually transmitted infections (STIs) such as chlamydia and gonorrhea. It is an effective antibiotic against these bacterial infections and helps prevent their spread.
  • Lyme Disease: Doxycycline is one of the antibiotics commonly used to treat Lyme disease, which is transmitted through tick bites. It can effectively target and eliminate the bacterium responsible for Lyme disease, particularly in the early stages of infection.
  • Malaria Prevention: In some regions where malaria is prevalent, Doxycycline may be prescribed as a prophylactic treatment to prevent malaria infection. It should be taken as directed and in combination with other preventive measures.
  • Other Infections: Doxycycline can also be used for various other infections, including urinary tract infections, eye infections, certain dental infections, and more, depending on the specific bacterial pathogens involved.

It’s important to note that Doxycycline is effective against a broad spectrum of bacteria, but it may not be suitable for all types of infections. The choice of antibiotic and the duration of treatment should be determined by a healthcare provider based on the specific infection, its severity, and the susceptibility of the bacteria causing it. Doxycycline is typically available in different forms, including for Injection and tablets, and is generally taken orally with or without food, as directed by a healthcare provider. It’s crucial to complete the full course of treatment, even if symptoms improve before the medication is finished, to ensure that the infection is fully eradicated and to prevent the development of antibiotic resistance.

How Does Doxycycline For Injection Work?

Doxycycline For Injection work as a broad-spectrum antibiotic to combat various bacterial infections. Doxycycline is a member of the tetracycline class of antibiotics, and its mechanism of action involves several key processes:

  • Inhibition of Protein Synthesis: Doxycycline interferes with the bacterial protein synthesis process. Within bacterial cells, ribosomes are responsible for assembling proteins necessary for bacterial growth and survival. Doxycycline binds to the bacterial ribosomes, specifically targeting the 30S ribosomal subunit. This binding prevents the addition of new amino acids to growing protein chains, leading to the inhibition of protein synthesis.
  • Bacteriostatic Action: Doxycycline’s primary action is bacteriostatic, which means it inhibits bacterial growth and replication. By halting protein synthesis, it prevents bacteria from reproducing and spreading, ultimately curbing the infection’s progression.
  • Effective Against a Broad Spectrum of Bacteria: Doxycycline is effective against a wide range of both gram-positive and gram-negative bacteria, making it a versatile antibiotic for various types of bacterial infections. It can target pathogens responsible for respiratory infections, skin and soft tissue infections, urinary tract infections, and more.
  • Anti-Inflammatory Properties: In addition to its antibacterial action, Doxycycline has anti-inflammatory properties. It can reduce inflammation associated with infections, making it particularly useful in the treatment of conditions like acne and certain respiratory infections.
  • Lipid Solubility and Tissue Penetration: Doxycycline possesses good lipid solubility, allowing it to penetrate various tissues effectively. This characteristic is valuable in treating infections that involve different body systems, such as respiratory tract infections and skin infections.
  • Long Half-Life: Doxycycline has a relatively long half-life, meaning it remains active in the body for an extended period after administration. This property allows for less frequent dosing, typically once or twice daily, making it convenient for patients.
  • Treatment of Intracellular Pathogens: Doxycycline is known for its ability to penetrate cells and combat intracellular pathogens. This is particularly important in the treatment of infections caused by bacteria that can reside inside host cells, such as Chlamydia and some types of bacteria responsible for pneumonia.

It’s important to use Doxycycline For Injection as prescribed by a healthcare provider and to follow the recommended dosage and duration of treatment for the specific bacterial infection being treated. Stopping the medication prematurely or not completing the full course of treatment may lead to incomplete eradication of the infection and the potential development of antibiotic resistance. Additionally, Doxycycline should not be used for viral infections, as it is not effective against viruses.

Benefits of Doxycycline For Injection :

  • Broad-Spectrum Antibiotic: Doxycycline is effective against a wide range of bacteria, both gram-positive and gram-negative, making it a versatile antibiotic for treating various bacterial infections.
  • Treatment of Respiratory Infections: Doxycycline is commonly used to treat respiratory tract infections, including bronchitis, sinusitis, and pneumonia. It helps clear infections, alleviate symptoms, and promote recovery.
  • Skin and Soft Tissue Infections: It is effective in treating skin and soft tissue infections, such as cellulitis, abscesses, and wound infections. Doxycycline helps control bacterial growth and facilitates healing.
  • Acne Management: Doxycycline is a valuable option for managing moderate to severe acne. It reduces inflammation associated with acne lesions and inhibits the growth of acne-causing bacteria.
  • Sexually Transmitted Infections (STIs): Doxycycline is used to treat STIs like chlamydia and gonorrhea. It effectively clears bacterial infections and prevents their spread.
  • Lyme Disease Treatment: It is used in the treatment of Lyme disease, particularly in the early stages. Doxycycline targets the bacterium responsible for Lyme disease and helps prevent complications.
  • Malaria Prevention: In malaria-endemic areas, Doxycycline is used as a prophylactic treatment to prevent malaria infection when combined with other preventive measures.

Side Effects of Doxycycline For Injection :

  • Gastrointestinal Disturbances: Common side effects may include nausea, vomiting, diarrhea, and abdominal discomfort. Taking Doxycycline with food can help reduce these symptoms.
  • Photosensitivity: Doxycycline can make the skin more sensitive to sunlight, increasing the risk of sunburn. It’s important to use sunscreen and protective clothing when exposed to the sun during treatment.
  • Esophageal Irritation: Doxycycline for Injection should be taken with plenty of water to prevent irritation of the esophagus and minimize the risk of esophagitis.
  • Allergic Reactions: Although rare, some individuals may experience allergic reactions to Doxycycline, which can manifest as rash, itching, swelling, severe dizziness, or difficulty breathing. Seek immediate medical attention if any of these symptoms occur.
  • Liver Effects: In rare cases, Doxycycline can affect liver function. Promptly report any signs of liver problems, such as yellowing of the skin or eyes (jaundice), dark urine, or persistent nausea, to a healthcare provider.
  • Dental Discoloration and Enamel Hypoplasia (in Children): Doxycycline can cause dental discoloration and enamel hypoplasia (underdevelopment) in children below eight years of age if used for prolonged periods.
  • Intracranial Hypertension: In rare cases, Doxycycline may lead to intracranial hypertension (increased pressure inside the skull), resulting in symptoms like severe headache, vision changes, and nausea. This condition requires immediate medical attention.

It’s essential to take Doxycycline For Injection as directed by a healthcare provider and to report any unusual or severe side effects promptly. In most cases, the benefits of treating bacterial infections with Doxycycline outweigh the potential risks associated with the medication. However, individual responses to medications can vary, so maintaining open communication with a healthcare provider is crucial for proper guidance and monitoring during treatment.

Frequently Asked Questions About Doxycycline For Injection ?

Certainly, here are some frequently asked questions (FAQs) about Doxycycline For Injection:

  1. What is Doxycycline For Injection used for?

Doxycycline For Injection is used to treat various bacterial infections, including respiratory tract infections, skin and soft tissue infections, and certain sexually transmitted infections. It is also used as a prophylactic treatment for malaria.

  1. How does Doxycycline For Injection work?

Doxycycline is an antibiotic that works by inhibiting the growth and spread of bacteria. It does this by interfering with the bacteria’s ability to produce proteins necessary for their survival.

  1. Is Doxycycline For Injection safe for everyone?

While generally safe, it may not be suitable for individuals with certain medical conditions or allergies. A healthcare provider will assess a patient’s medical history before prescribing this medication.

  1. Is it safe to use Doxycycline For Injection during pregnancy and breastfeeding?

The use of Doxycycline during pregnancy, especially during the second and third trimesters, may affect fetal development and should be carefully considered under medical supervision. It can also pass into breast milk, so the risks and benefits should be discussed with a healthcare provider.

  1. How is Doxycycline For Injection administered?

It is typically administered by a healthcare professional as an intravenous (IV) infusion in a healthcare setting. The dosage and duration of treatment depend on the specific infection being treated.

  1. What are the common side effects of Doxycycline For Injection?

Common side effects may include nausea, vomiting, diarrhea, and skin sensitivity to sunlight (photosensitivity). Less commonly, it can cause allergic reactions and disturbances in liver function.

  1. Is it effective against all types of bacterial infections?

Doxycycline is effective against a wide range of bacteria, but its suitability depends on the specific bacterial strain and the results of sensitivity testing.

  1. Can Doxycycline For Injection be used in pediatric patients?

Yes, it can be used in pediatric patients, but the dosage is adjusted based on the child’s age and weight. It is commonly used to treat infections in children.

  1. How long should I take Doxycycline For Injection?

The duration of treatment varies depending on the type and severity of the infection. It is essential to complete the full course of treatment, even if symptoms improve before the medication is finished.

  1. Can I consume alcohol while taking Doxycycline For Injection?

It is generally recommended to avoid alcohol while taking Doxycycline as it may reduce the medication’s effectiveness and increase the risk of side effects.

Patients should follow their healthcare provider’s instructions regarding the use of Doxycycline For Injection and report any unusual symptoms or side effects during the course of treatment.

As Doxycycline For Injection Exporters; We can cater to export business queries from the following geographies. We are exporting our Doxycycline For Injection product in the Following Countries-

Russia and CIS Countries: Azerbaijan, Armenia, Belarus, Georgia, Kazakhstan, Kyrgyzstan, Moldova, Russia, Tajikistan, Turkmenistan, Uzbekistan and Ukraine

GCC/ Middle East Countries: Saudi Arabia, Yemen, Oman, Bahrain, UAE, Lebanon, Jordan, and Iraq.

African Countries: Nigeria, Tanzania, Sudan, Zambia, Benin, Angola, Liberia

Southeast Asia: Cambodia, Indonesia, Laos, Malaysia, Myanmar, Philippines, Singapore, Thailand, Vietnam, Brunei Darussalam

Other Asian Countries: Nepal, Myanmar, Malaysia, Cambodia, Bhutan, Sri Lanka, Mauritius

Doxycycline For Injection Regulatory Documents:

  • Certificate of Analysis (COA)
  • Method of Analysis (MOA)
  • Stability Data (Accelerated stability / Long-term stability / Zone 4b)
  • CTD Dossier / ACTD Dossiers / eCTD Dossiers
  • Certificate of Pharmaceuticals Product (COPP)
  • Free Sale Certificate (FSC)

Contact the most reliable manufacturer of Doxycycline For Injection , Taj Pharmaceuticals Limited, to get bulk quantities at a reasonable price.

To Place Orders:

Direct line: +91 8448 444 095 / WhatsApp +91 74 0000 9975 / 74 0000 9976
E-Mail: info@tajpharma.com 
Toll free: 1-800-222-434 / Toll free: 1-800-222-825
General EPA BX: +91 22 2637 4592 / +91 22 2637 4593
Fax No: +91 22 2634 1274