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Linking DNA methylation to Aspirin use and breast cancer survival

{Taj Pharmaceuticals Limited} : Top Mumbai [generic] manufacturing company What Are Authorized Generics? Authorized generics might just be the answer for drug manufacturers whose patents for their branded drugs have expired. Instead of risking the loss of market share when other drug companies enter the generics marketplace, the brand name manufacturers could develop their own generics. An authorized generic is exactly the same product as an approved branded drug, but is marketed without the brand name on the label. Usually sold at a lower price, it can be marketed by a branded drug company or by another company with the brand company’s permission. “By making an authorized generic, a brand manufacturer gets a jump start on the competition as generics start to appear,” says Karen Berger, PharmD, a staff pharmacist at Plymouth Park Pharmacy in Fair Lawn, NJ. “Authorized generics, which are identical to the brand, should not be confused with a branded generic that has gone through the abbreviated new drug application (ANDA) process and is assigned a name other than its chemical name,” she says. Leaving nothing to chance: “While a separate NDA is not required for marketing an authorized generic, FDA requires that the NDA holder notify the […]

{Taj Pharma} Users of alternative remedies tend to refuse cancer treatments, with increased mortality

How carb counting works Aims of carb counting Carb counting tips Understanding carb-heavy foods Summary

Down To Earth talks to doctors to get a sense of the ailments that residents of NCR are exposed to It has been more than a week of breathing heavily polluted air for Delhiites. It is safe to say that for more than 150 hours they breathed a toxic cocktail, with the air quality ‘severe’ or ‘severe +’ since October 30. Particulate matters (PM) 2.5 and 10 remained at least five times more their safe standards. These ultrafine particles can enter the respiratory system and reach the bloodstream. On an average, a person breathes 25,000 times a day. For those living in Delhi and the National Capital Territory (NCT) regions, this means breathing toxic air 25,000 times a day. Toxins once deposited in lungs cannot be cleansed.  What does such continued exposure to ultrafine PM does to our bodies?  According to doctors, such continued inhalation of toxic gases affects all organs and not just lungs. It even has the potential to cause hormonal imbalances. Being in such an environment full of pollutants constantly also affects the central nervous system of the brain. “Impairment in concentration abilities has been seen. There can be other short-term disturbances to what you normally do,” Prashant Saxena, who heads the department of Pulmonology […]

Warming catalyses antimicrobial resistance Warmer climatic conditions are giving rise to infectious diseases like malaria, dengue, gastroenteritis, wound infections, septicaemia and cholera, caused by Vibrio bacteria, warned the Lancet Countdown Report 2019 on Health and Climate Change. The annual update was on 42 indicators across five topics: Climate change impacts, exposures, and vulnerabilityAdaptation, planning, and resilience for healthMitigation actions and health co-benefitsEconomics and financePublic and political engagement The report identified the prevalence of infectious diseases due to climate change among the climate change indicators. As an example of how warmer conditions affect health, it cited how the number of days for the Vibrio bacteria to reproduce and spread has doubled since 1980. Also, increased sea-surface temperature increased the risk of Vibrio cholerae infections, Rachael Davies, communications consultant with Lancet told Down To Earth. The climactic conditions also favoured the quick spreading of other pathogens, Davies added. The report released November 13, 2019, warned that 2018 was second on record for suitable conditions for the transmission of diarrhoeal disease and wound infections from Vibrio (since 2000). Children were more susceptible to diseases such as diarrhoea and dengue.  Warmer climate also acted as a catalyst in spreading antimicrobial-resistance (AMR).   It has already emerged in […]

Big Pharma Bets on Body’s Garbage-Disposal System to Beat Cancer New drugs called “degraders” could take disease-causing proteins out with the trash. Craig Crews pioneered protein degrader drug technology. At their most basic level, many of the deadliest diseases are caused by nests of misguided proteins. Most medicines work by attaching themselves to these proteins and temporarily shutting them down. In the 1990s, Yale University scientist Craig Crews and a colleague had a radical idea: What if a drug could destroy a bad protein by making it a target of the body’s own molecular trash disposal machines? For years, the idea remained a lab curiosity. Biotech investors wouldn’t initially back a company based on the concept, which Crews and a few other academics labored to prove could be a practical way to make drugs. The field got a big boost earlier this decade when scientists started discovering that some of the most successful medicines turned out to work by piggybacking onto these human trash collectors. Now it’s become one of the hottest new technologies for making pills. Crews and a biotech he founded, Arvinas Inc., are racing some of the world’s biggest pharmaceutical and biotech companies—Novartis, Amgen, and Gilead Sciences—to […]

An angiogram is an X-ray of the blood vessels. They can provide images of the blood vessels in many different organs. As a result, they often help doctors diagnose conditions affecting the heart, brain, arms, or legs. Angiograms can help doctors detect blood vessel abnormalities, including weakened blood vessels, plaque deposits, and blood clots. This articles discusses why doctors use angiograms, how they perform them, and the risks and side effects associated with the procedure. It also provides tips for people recovering from an angiogram. What is an angiogram? The term “angiogram” refers to a number of diagnostic tests that doctors can use to identify blocked or narrow blood vessels. Angiograms also help doctors diagnose a range of cardiovascular diseases, including coronary atherosclerosis, vascular stenosis, and aneurysms. To perform a traditional angiogram, a doctor inserts a long, narrow tube called a catheter into an artery located in the arm, upper thigh, or groin. They will inject contrast dye into the catheter and take X-rays of the blood vessels. The contrast dye makes blood vessels more visible on X-ray images. Not all angiograms involve X-ray machines, however. Doctors can also perform angiograms using CT scans and MRI scans. A doctor may […]

Compliance and Competitiveness in Indian Pharmaceuticals Industry: by Ms. Priyanka Singh Director Taj Pharma Group The word “compliance” in India took on a whole new meaning in 2012 when key Indian Pharma Products exports pushed to USA and European Markets without much apprehensions. In the sophisticated Indian pharmaceutical market, some local firms are increasingly looking to export not only to the Africa, Russia but other highly European regulated markets like the One such firm is Taj Pharma Group, a Mumbai based Generics Medicines exporter and Manufacturer. Compliance and Competitiveness in Indian Pharmaceuticals Industry: by Ms. Priyanka Singh Director Taj Pharma Group The word “compliance” in India took on a whole new meaning in 2012 when key Indian Pharma Products exports pushed to USA and European Markets without much apprehensions. That new status, known as the “Generalised System” of Preferences plus is linked to the implementation of 27 international conventions including labor rights, sustainable development, and good governance. In the sophisticated Indian pharmaceutical market, some local firms are increasingly looking to export not only to the Africa, Russia but other highly European regulated markets like the One such firm is Taj Pharma Group, a Mumbai based Generics Medicines exporter and Manufacturer. […]

You should check the registration number of the online pharmacy and cross-check it at the website of the regulatory body. The names of fake online drug stores will be blacklisted by the regulatory body. You should check whether an online pharmacy asks for a prescription before dispatching your medicines.

Read more on what is lung cancer here. Etoposide is the chemotherapy drug and is classified as a plant alkaloid (Epipodophyllotoxin) and a topoisomerase II inhibitor. Plant alkaloids are substances that are made from plants. Etoposide is available under the trade name VP-16 or Toposar. The drug acts by inhibiting topoisomerase II, thereby inhibiting DNA synthesis. Availability, Dosage and Administration of Etoposide Etoposide is available in tablet form and can be taken orally. It is also available in injectable form and can be administered as an infusion into the patient’s vein, it can be a short infusion or can be an infusion that lasts for over 24 hours. Availability In the oral form it is available as capsule with the dose strength of 50mg and in the injectable form it is available as 20mg/ml. Uses Small cell lung cancerNon-small cell lung cancerGerm cell tumorsNon-Hodgkin’s LymphomaStomach cancerAs a high dose therapy in the setting of transplantation. Dosage The recommended dose depends on the indication or use. It is generally given at 100 to 120 mg/m2, for 1 to 3 days, every 3 weeks. Side effects Most people do not experience side effects while being treated with etoposide. Even if side effects […]

Are you up to date on recent developments in cystic fibrosis (CF) care? Thanks to advancements in medical science, the outlook for people with CF has improved a lot in recent decades. Scientists continue to develop new drugs and strategies to improve the lives of people with CF. Let’s take a look at some of the latest developments. Updated guidelines to improve personalized care In 2017, experts from the Cystic Fibrosis Foundation released updated guidelines for diagnosing and classifying CF. These guidelines might help doctors recommend more personalized approaches to treating CF. Over the past decade, scientists have developed a better understanding of the genetic mutations that can cause CF. Researchers have also developed new drugs to treat people with certain types of genetic mutations. The new guidelines for diagnosing CF might help doctors determine who is most likely to benefit from certain treatments, based on their specific genes. New drugs to treat the underlying cause of symptoms CFTR modulators can benefit some people with CF, depending on their age and the specific types of genetic mutations they have. These drugs are designed to correct certain defects in CFTR proteins that cause symptoms of CF. While other types of medication […]

Lung cancer mortality expected to decrease over the next half century

The first biosimilar in India was approved in 2000, and, with the help of legislation and regulation from the Indian Government, the market has continued to grow since, reaching a value of $2.2bn in 2017. However, biosimilars remain challenging to manufacture for Indian pharmaceutical companies, at the emerging end of the market. India has firmly established itself in the global pharmaceutical market; it has been predicted that India will be the sixth largest market for pharmaceuticals by 2020, and the country exported pharmaceutical products worth more than $17bn in 2017-8. Indian pharmaceutical companies are especially known for producing generics, identical copies of branded drugs marketed under different names once the patent for the original drug has run out. Many of these companies are starting to move into the global biosimilars market. According to Associated Chambers of Commerce of India’s 2017 report, biosimilars are worth $2.2bn out of the $32bn total Indian pharmaceutical market and are expected to reach $40bn by 2030, which represents a 30% compound annual growth rate. This growth will be aided by a range of biologic patents expiring in the next few years. Biosimiliars are medicines that are highly similar and clinically equivalent to complex, biologic medicines […]

Biosimilar drugs are often confused with generic drugs. Both are marketed as cheaper versions of costly name-brand drugs and are designed to have the same clinical effect as their pricier counterparts. But biosimilar drugs and generic drugs are very different. Biosimilar drugs are often confused with generic drugs. Both are marketed as cheaper versions of costly name-brand drugs. Both are available when drug companies’ exclusive patents on expensive new drugs expire. And both are designed to have the same clinical effect as their pricier counterparts. But biosimilar drugs and generic drugs are very different, mainly because while generic drugs are identical to the original in chemical composition, biosimilar drugs are “highly similar,” but close enough in duplication to accomplish the same therapeutic and clinical result. Another key difference is that generics are copies of synthetic drugs, while biosimilars are modeled after drugs that use living organisms as important ingredients. But many experts hope the two will share a critical commonality and that, like generics, biosimilars will dramatically lower the cost of biologic drugs. “ Branded drugs are either synthetic, meaning they’re made from a chemical process, or biological, meaning they’re made from living sources. Synthetic branded drugs can be exactly […]

Carcinogens Have Infiltrated the Generic Drug Supply – {Taj Pharmaceuticals} Valsartan Tablets are free of all Impurities. An FDA quality-control nightmare reveals how impurities end up in blood pressure pills. Valsartan The chemical N-Nitrosodimethylamine, or NDMA, is a yellow liquid that dissolves in water. It doesn’t have an odor or much of a taste. It’s known to cause cancer in animals and is classified as a probable carcinogen in humans—it’s most toxic to the liver. A single dose of less than a milligram can mutate mice cells and stimulate tumors, and 2 grams can kill a person in days. An Oklahoma man poisoned the family of an ex-girlfriend in 1978 by pouring a small vial of NDMA into a pitcher of lemonade. In 2018 a graduate student in Canada sickened a colleague by injecting the chemical into his apple pie. NDMA no longer has industrial uses—it was once added to rocket fuel—but it can form during industrial processes at tanneries and foundries as well as at pesticide, dye, and tire makers. It can be found in drinking water disinfected with chloramine. It’s in tobacco smoke, which is one reason secondhand smoke is dangerous, and it’s what makes eating a lot […]

Vegetarian diet more effective for weight loss and metabolism

How does high blood sugar (hyperglycemia) feel? Symptoms | Causes Healthy blood sugar | When to see a doctor

Coffee compound may prevent type 2 diabetes

New research in mice shows “for the first time” that scientists can use protons to administer radiation therapy in a matter of milliseconds, killing cancer cells while protecting healthy tissue. Over half of the people with a cancer diagnosis receive radiation therapy. Radiation damages the DNA of cancer cells, either slowing their progression or killing them. However, this is a slow process; radiation does not destroy cancer cells right away — sometimes it takes weeks of treatment to damage the DNA of the cells enough to kill them. A further reason why radiation treatment can take several weeks is that the therapy is most likely to succeed when cancer cells are growing and dividing into new cells. So, spreading the treatment over a long period increases the chances that the radiation will target cancer cells when they are in a growing phase. Finally, administering radiation in small, daily doses helps protect healthy cells by giving them more time to repair. But new research suggests that there may be a way to administer radiation at record speed while also protecting healthy tissue. The innovative technique is called FLASH, or ultra-high dose rate radiotherapy, and according to previous research, it uses electrons […]

Ranitidine is a commonly prescribed medicine for countering acidity and is on the WHO’s Model List of Essential Medicines. Our drug Ranitidine Tablets are safe: Taj Pharmaceuticals Amid a raging controversy over commonly used heartburn drug Ranitidine, Mumbai-based Taj Pharmaceuticals Limited today said that its formulation drug is safe. The company said that the test results found that Taj Pharmaceuticals’ Ranitidine tablets was within the “acceptable limits” for the presence of a probable cancer causing substance. On 29th September 2019 US FDA had raised a global alarm over the presence of a probable cancer causing substance—NDMA or N-Niteosodimethylamine—in some Ranitidine medicines. The company is likely to continue Ranitidine drug sale, following the report. “The Company intends to provide additional updates in the next coming days, including potential recommencement,” it said in a statement. Taj Pharma Ranitidine Free of ALL NDMA / NDEA Impurities NDMA Risk Assessment Report is done in much more advanced for all potential APIs (Valsartan) on our ROS of Ranitidine Hydrochloride and analyzed few batches for NDMA content in Ranitidine HCL API by validated LC-MS/MS and GC-MS methods. As per our initial investigation and assessment report, it is found that the formation of NDMA in ROS of our […]

Is Parkinson’s disease passed on through genetics?

{Taj Pharmaceuticals} Stomach cancer symptoms, diagnosis and treatment: STOMACH cancer is one of the most common types of cancer and one of the top causes of cancer deaths worldwide. Survival rates for the deadly disease stand at just 14 percent. With these worrying statistics its imperative for one to spot the early signs of stomach cancer, and feeling a certain burning sensation could mean you’re at risk. Stomach cancer is characterised by a growth of cancerous cells within the lining of the stomach. Also known as gastric cancer, it’s a type of cancer that is difficult to diagnose. The National Cancer Institute (NCI) estimates there’ll be approximately 28,000 new cases of stomach cancer in 2017. Since stomach cancer usually doesn’t cause any early symptoms, it often goes undiagnosed until after it spreads to other parts of the body. Feeling an acid reflux that persists and a burning sensation could signal the deadly disease. Stomach cancer is directly linked to tumours in the stomach. Risk factors for the disease include a group of blood cancers, a common stomach infection that can sometimes lead to ulcers, tumours in other parts of the digestive system or abnormal growths of tissue that form on […]

Going vegan could prevent type 2 diabetes

Schedule daily ‘me’ time and start practicing mindfulness, says Hong Kong-based life coach Steffi Lopez Gonzalez As 2020 looms on the horizon, many people see it as an opportunity to better themselves and start working on new projects and goals through New Year’s resolutions. Often, our resolutions revolve around things like getting fit, getting better grades or spending less money. Mental health often takes a back seat, despite the fact that it affects our emotional, physical and social well-being. With the help of certified NLP Life Coach and speaker Steffi Lopez Gonzalez, who runs the Hong Kong-based Your Life Your Playground, which focuses on yoga, meditation and life coaching, we’ve assembled a list of New Year’s resolutions you can make to improve your mental health in the new year.  The quest for perfection can lead to depression – don’t let it take over Take one day a week off social media “Social media has addictive qualities,” says Lopez Gonzalez.  “It’s easy to become obsessed with the rewards of ‘likes’ or ‘retweets’ and get caught up in chasing the approval of others instead of being involved and interested in your own life and the lives of those around you.” Not only can […]

Indian pharmaceutical market update Generic affordable alternatives are much more easily available India With around 1.3 billion residents, India is home to just a fraction fewer people than China, the world’s most populous nation. India is also developing fast, consistently posting annual gross domestic product (GDP) growth rates in the mid-to-high single digits since the turn of the millenium, and outpacing all other nations in 2018 with growth of 7.3%. The country’s GDP is now roughly equivalent to that of the UK in nominal terms. Adjusting for purchasing power differences it is the third largest, behind the USA and China. Despite these impressive figures, hundreds of millions of people live in poverty. India remains a developing nation, with a healthcare system to match. At around $30 billion, the country’s pharmaceutical market generates revenues roughly equivalent to those of the newly-enlarged Japanese drugmaker Takeda Pharmaceutical (TYO: 4502). The market for pharmaceutical products does not, therefore, move the needle for global drugmakers, but as it continues to grow in line with wider economic development, new opportunities will continue to emerge. “By 2020, the value of pharma products sold in the country is is expected to reach $55 billion.” By 2020, the value […]

Solving the ‘parking’ problem in the drug monopoly game Drug prices are too high. One reason is that brand-name drug firms delay generic entry. Another is that generic companies themselves delay entering the market. And they delay not only their entry but those of other generics as well. Congress is considering addressing this “parking” of generic exclusivity. One proposal, the BLOCKING Act of 2019, would not solve the problem. Another, the recently-introduced Expanding Access to Low-Cost Generics Act, would. The BLOCKING Act has received significant attention. Supported by the White House and included in legislation approved overwhelmingly by the Senate HELP Committee and House Energy & Commerce Committee, the Act provides that a generic that does not quickly enough receive FDA approval will lose exclusivity. It promises to address the “parking” of exclusivity. But it would not. Why? Because there’s no guarantee, a later generic will enter the market just because the first filer has lost exclusivity. These later generics might not be ready to launch or might be unwilling to challenge the first filer’s patents or launch “at-risk” (before a court decision). In addition to the BLOCKING Act not introducing competition, the first filer could lose exclusivity through no […]

{Taj Pharmaceuticals} Manufacturing Drug that prevents half of [Breast cancers growth]: A drug that halves a woman’s risk of breast cancer continues to work long after they stop taking it, say researchers. Anastrozole blocks the production of the hormone oestrogen, which fuels the growth of many breast cancers. It is already available on the NHS, but researchers at Queen Mary University of London said only a tenth of eligible women were receiving it. Cancer Research UK said the findings were reassuring. Who can take it? Anastrozole can be given only after the menopause because it cannot suppress oestrogen in younger women. It is already used as a treatment once breast cancer has been discovered, but now trials are focusing on preventing cancers emerging in the first place. Previous research, has shown anastrozole halves the risk of breast cancer during the five years women took the drug. But now, trials on 3,864 women show those taking it had 49% fewer breast cancers, even seven years after stopping treatment. In other words – the benefit lasts. The findings have been published in the Lancet and presented at the San Antonio Breast Cancer Symposium in Texas. “Breast cancer is the commonest cancer in […]

Govt’s generic push will dent Rs 90,000-cr branded pharma market Pharma companies may soon start wooing chemists as the Narendra Modi government plans to make it mandatory for doctors to prescribe pure-generic drugs, instead of branded generics as they do now. Medicines Though the plan was first announced in this year’s Budget, the prime minister spoke about it for the first time at a public event on Monday. The health ministry has now started working on amending the Drugs and Cosmetics Act to this effect. “Indian patients may face quality issues without price benefit as intense competition among marketers will lead to incentivising a chemist,” says D G Shah, secretary-general of the Indian Pharmaceutical Alliance. India, like most of other emerging markets, is predominantly a branded generics play with a 90 per cent share in the Rs 1-lakh-crore market. Which means that drug makers sell these off-patent drugs through their relationships with doctors. In developed countries such as the US, only patented drugs are sold under a brand, which is marketed through their ties to doctors. Off-patent drugs are sold only as pure generic, without using any brand name. It helps in making pure generics cheaper. It is this nexus […]

While over 50 different biosimilars already exist in the Indian market, the big money lies launching these drugs in Europe and the United States It has been more than a decade since Indian pharmaceutical companies began looking at the biosimilar opportunity. It is not an easy space to be in and quite unlike their traditional stronghold of generics. However, it is a space that is linked to the nature of future drugs – today, as is often quoted by pharma experts, one out of every three new drugs approved in the global matkets is a biotech drug, specially in fields like cancer care. While over 50 (and counting) different biosimilars already exist in the Indian market, the big money lies launching these drugs in Europe and the United States. So far, hardly a couple of Indian companies have been able to do this and much of this happened in the decade that has just concluded. In February 2015, Intas Pharmaceuticals became the first Indian company to get a biosimilar registered – the biotech drug Filgratsim under the brand Accofil – in the European Union. It is now getting ready to foray into US with more products. “We launched pegylated granulocyte-colony […]

Half of pediatric cancers undiagnosed and untreated worldwide Nearly one in two children with cancer are never diagnosed and may die untreated, according to a a new model proposed in a study published in The Lancet Oncology  by Zachary Ward and colleagues  from Harvard University T.H. Chan School of Public Health. In fact, the model estimates that there were 397.000 childhood cancer cases globally in 2015, while only 224,000 had been previously recorded as diagnosed that year, leading ultimately the researchers to say that over 43% of childhood cancer cases were undiagnosed. But there was substantial regional variation: it ranges from 3% in both Western Europe (120 undiagnosed cases out of 4,300 total new cases) and North America (300 of 10,900 cases), to 57% (43,000 of 76,000 new cases) in Western Africa. With such path, at current levels of health system performances, If no improvements are made, the study authors estimated that nearly three million out of 6.7 million total cases will be missed between 2015 and 2030. Accounting for underestimation is vital: accurate estimates of incidence are important for policy makers, however, many countries do not have cancer registries that quantify that incidence (and often even if they do […]

The crisis in access to essential medicines in India: key issues which call for action Author: Anurag Bhargava, SP Kalantri | DOI: https://doi.org/10.20529/IJME.2013.028 Abstract The government is planning to introduce free generic and essential medicines in public health facilities. Most people in India buy healthcare from the private sector, a compulsion that accounts for a high proportion of healthcare-related expenditure. To reduce the burden of healthcare costs, the government must improve availability and affordability of generic and essential medicines in the market. It can do so because India’s large pharmaceutical industry is a major source of generic medicines worldwide. In this article, we discuss three factors that have impeded access to generic and essential medicines: mistaken notions among policymakers, prescribers and patients about branded drugs and generic drugs in India; high prices of medicines due to the progressive dismantling of the system of regulation of medicine prices, and a drug approval and regulatory system that allows medicines (including fixed dose combinations) of doubtful efficacy, rationale, safety and public health relevance to dominate the market at the cost of access to affordable generic and essential medicines. The consequences of ill-health and wasted expenditure on drugs raise issues of public health ethics. […]

Kids born with assisted reproduction are not at higher risk of getting cancer Recently, Allison and Honjo have been awarded with the Nobel prize for their findings leading to the new cancer treatment approaches known as immune checkpoint inhibitors (ICIs). Thanks to these discoveries in fact, the management of the disease has profoundly changed, producing remarkable results on several tumors, even if checkpoint inhibitors have significant side effects, that according to an analysis published in Jama are still poorly known by many health professionals. It is “urgent”, according to authors, “to identify who is at highest risk of severe outcomes, and then develop evidence-based therapies to manage toxicity”. Understanding these adverse effects is essential not for oncologist only, but for every physician in any discipline, as said by Douglas B. Johnson, MD, of Vanderbilt University, Nashville, Tennessee, and colleagues. Indeed, they underlined what are the most common effects which occur in practice in an article published online in JAMA. Many organs can be involved, commonly the skin, the gastrointestinal tract, the lungs, endocrine organs, musculoskeletal, renal, nervous, hematologic, cardiovascular, and ocular systems, thus counting such side effects as a problem to be faced jointly among the various physicians. Autoimmune events are […]

Dead bodies are revealing the secrets of how cancer kills : {Taj Pharmaceuticals}

Diabetes | Diabetes Causes | Diabetes Diagnosis | Diabetes Outlook | Diabetes Risk factors | Diabetes Symptoms | Diabetes Treatment and prevention | Diabetes Type 1 | Diabetes Type 2 | type 2 diabetes | types 1 Diabetes

Radiation therapy | Immunotherapy | Hormone therapy | Targeted therapy | Making a decision | Outlook | Takeaway Doctors use chemotherapy either as a first-line therapy or in combination with other treatments, such as surgery. If chemotherapy does not work, a person may need to consider other treatment options.

Immunotherapy comparable to chemo for some advanced stomach cancers [Taj Pharma Global Cancer initiative]

The symptoms of frontotemporal, or early onset, dementia can appear as early as age 40. Have researchers found a new way to treat this condition using antibiotics?

China coronavirus: All you need to know – A new virus has killed 81 people in China and infected almost 3,000 people, with cases confirmed in several countries. Coronavirus: Everything you need to know Health authorities around the world are grappling with an outbreak of a new coronavirus, which originated in the Chinese city of Wuhan. At least 81 people have died in China and almost 3,000 have been infected worldwide. What is a coronavirus? Coronaviruses are a large family of viruses that cause illnesses ranging from the common cold to more severe diseases such as Severe Acute Respiratory Syndrome (SARS) and Middle East Respiratory Syndrome (MERS), according to the World Health Organization (WHO). They circulate in animals and some can be transmitted between animals and humans. Several known coronaviruses are circulating in animals that have not yet infected humans. The new coronavirus has been named novel coronavirus (2019-nCoV). It is the seventh coronavirus known to affect humans. What are the symptoms? Common signs of infection include fever, coughing and breathing difficulties.  In more severe cases, infection can cause pneumonia, SARS, kidney failure and death. The incubation period of the new coronavirus is thought to be between one and 14 […]

Never too late to quit: protective cells could cut risk of lung cancer for ex-smokers {Taj Pharma}

Here’s the timeline of how the Coronavirus outbreak evolved from Wuhan city in China and spreading its tentacles across the world. Update: DBS evacuates 300 after one is infected – Singapore’s DBS bank has evacuated 300 employees after one employee was confirmed to have contracted the coronavirus. Japan cruise cases increase to 174 – The total confirmed cases on the Diamond Princess cruise ship, quarantined in Japan, have surged to 174. Death toll reaches 1,115; recoveries rise – Deaths from the new coronavirus have reached 1,115, while the total number of cases exceeded 45,100, including 44,653 reported in mainland China by authorities as of the end of 11 February. – According to NHC official Mi Feng, the proportion of recovered patients in China increased to 8.2% as of 10 February, from 1.3% on 27 January. WHO gives name to new coronavirus disease – The WHO has officially named the disease caused by the new coronavirus as ‘Covid-19’. – Ukraine is screening five of its citizens for the novel coronavirus, Health Minister Zoriana Skaletska said at a press briefing on 11 February. – According to Skaletska, three of the five suspected patients returned from China while the remaining two were in […]

Online mindfulness-based cognitive therapy to improve lingering depression: {Taj Pharmaceuticals}

This is how HIV decides to become active Researchers have found the molecular mechanism underpinning HIV’s decision to remain in an active or dormant state. This may lead to new therapies that work by keeping the virus in a permanently dormant state. The study, led by a team from the Gladstone Institutes in San Francisco, CA, features in a paper now published in the journal Cell. The findings may also explain cell fate decisions that occur elsewhere in biology — such as how stem cells decide whether to remain as stem cells or differentiate into specialized cells, including brain or heart cells, when they divide. Senior study author Prof. Leor S. Weinberger, the director of the Center for Cell Circuitry at the Gladstone Institutes, likens the process to how we “hedge our bets” when we make decisions about financial investments. To “protect against volatility in the market,” we may choose to place some funds in high-risk stocks with potentially high yields and the rest in low-risk, low-yield options. “Similarly,” he explains, “HIV covers its bases in a volatile environment by generating both active and dormant infections.” HIV latent reservoir: Once it enters the human body, HIV inserts its genetic material […]

Coronavirus outbreak shows Asia needs to step up infection preparation [Taj Pharma]

Combining carbs and sweeteners could affect insulin sensitivity :{Taj Life Sciences} Eat good; Look good

Every country needs to take boldest actions to stop COVID-19

Taj Pharmaceuticals Biotechnological Division has announced the research in order to create an mRNA vaccine against SARS-COV-2 (coronavirus). Development will be based on previous pipelines for mRNA-oncovaccines creation: an area where the company has a great expertise. The first animal studies are scheduled for the end of April.