post-title portfolio-title Vinblastine Sulphate for Injection USP 10mg (Veluterin) 2023-02-23 07:39:56 no no

Vinblastine Sulphate for Injection USP 10mg (Veluterin)

GENERIC NAME OF THE MEDICINAL PRODUCT:

Vinblastine Sulphate for Injection USP 10mg

QUALITATIVE AND QUANTITATIVE COMPOSITION:

Vinblastine Sulphate for Injection USP 10mg
Each vial contains:
Vinblastine Sulphate USP…….10mg
Excipients…………………………….q.s.

THERAPEUTIC INDICATION:

Vinblastine Sulphate to treat a number of types of cancer. This includes Hodgkin's lymphoma, non-small cell lung cancer, bladder cancer, brain cancer, melanoma, and testicular cancer.

DIRECTION OF USE:

For Intravenous infusion only.
Add sterile water for injection USP. Shake to dissolve, if product does not dissolve immediately allow to stand at room temperature until solution is obtained.

CAUTION & WARNING:

CAUTION: This injection should not be used if it contains visible particulate matter after reconstitution. Fatal if given Intrathecally, for Intravenous use only.
WARNING: Cytotoxic Agent: To be sold by retail on the prescription of an Oncologist/ Cancer Hospital only.
Cytotoxic special handling procedures see insert
FLIP-OFF SEAL IS PROVIDED FOR TAMPER EVIDENCE.
Discard Unused portion.
Keep out of the reach of the children.

STORAGE & DOSAGE:

Storage: Store vials at 20°C to 25°C (68° to 77° F); excursions permitted between 15°C to 30°C (59° to 86° F) [See USP Controlled Room Temperature]. Protected from light. Avoid excessive heat, over 40°C [104° F].
Dosage: As directed by an Oncologist.

Vinblastine Sulphate for Injection USP 10mg (Veluterin) Technical Specification:

Product Name:Vinblastine Sulphate for Injection USP 10mg
Brand Name:Veluterin
Strength:10mg
Dosage Form:Lyophilized
Dry Powder for Injection
Packing:SINGLE USE VIAL
Route of Administration:For I.V. infusion only.
Pack Insert/Leaflet:PIL (Patient Information Leaflet), SmPC (Summary Product Characteristics)
Regulatory Documents:COA, MOA, COPP, FSC, Stability Studies, GMP, CTD Dossier
Therapeutic use:Anti-Cancer
Indication: Vinblastine Sulphate to treat a number of types of cancer. This includes Hodgkin’s lymphoma, non-small cell lung cancer, bladder cancer, brain cancer, melanoma, and testicular cancer.
Storage:Store between 2°C to 8°C (36° F to 46° F) in a refrigerator. Do not freeze. Protect from light.

GENERIC NAME OF THE MEDICINAL PRODUCT:

  • Vinblastine Sulphate for Injection USP 10mg

QUALITATIVE AND QUANTITATIVE COMPOSITION:

  • Vinblastine Sulphate for Injection USP 10mg
    Each vial contains:
    Vinblastine Sulphate USP…….10mg
    Excipients…………………………….q.s.

THERAPEUTIC INDICATION:

Vinblastine Sulphate to treat a number of types of cancer. This includes Hodgkin’s lymphoma, non-small cell lung cancer, bladder cancer, brain cancer, melanoma, and testicular cancer.

DIRECTION OF USE:

For Intravenous infusion only.

Add sterile water for injection USP. Shake to dissolve, if product does not dissolve immediately allow to stand at room temperature until solution is obtained.

CAUTION & WARNING:

CAUTION: This injection should not be used if it contains visible particulate matter after reconstitution. Fatal if given Intrathecally, for Intravenous use only.

WARNING: Cytotoxic Agent: To be sold by retail on the prescription of an Oncologist/ Cancer Hospital only.

Cytotoxic special handling procedures see insert

FLIP-OFF SEAL IS PROVIDED FOR TAMPER EVIDENCE.

Discard Unused portion.

Keep out of the reach of the children.

STORAGE & DOSAGE:

Storage: Store vials at 20°C to 25°C (68° to 77° F); excursions permitted between 15°C to 30°C (59° to 86° F) [See USP Controlled Room Temperature]. Protected from light. Avoid excessive heat, over 40°C [104° F].

Dosage: As directed by an Oncologist.

Why Taj Pharmaceuticals?

Taj Pharma stands as a beacon of trust and excellence in the world of pharmaceuticals, offering a reliable source of Vinblastine Sulphate for Injection USP. With our unwavering commitment to quality and innovation, we have become the preferred choice for healthcare professionals and patients alike. Taj Pharma’s Vinblastine Sulphate for Injection USP is meticulously crafted to meet the highest industry standards, ensuring safe and effective treatment options. Our dedication to patient well-being sets us apart. We understand the critical importance of every dose, which is why we adhere to rigorous quality control measures. Choose Taj Pharma for your healthcare needs, and discover why our commitment to your health makes all the difference. Your health is our priority, and excellence is our promise.

What is Vinblastine Sulphate for Injection USP and its use?

Vinblastine Sulphate for Injection USP is a medication used in the treatment of various types of cancer. It belongs to a class of drugs known as vinca alkaloids and is derived from the periwinkle plant (Catharanthus roseus). Here’s an overview of Vinblastine Sulphate for Injection USP and its common uses:

Uses:

  • Active Ingredient: The active ingredient in Vinblastine Sulphate for Injection USP is vinblastine sulfate.
  • Cancer Treatment: Vinblastine is primarily used as a chemotherapy medication to treat various types of cancer, particularly those that affect the blood or lymphatic system. Common cancer types treated with vinblastine include:
    Hodgkin’s lymphoma
    Non-Hodgkin’s lymphoma
    Testicular cancer
    Breast cancer (in combination with other chemotherapy agents)
    Certain types of lung cancer
    Kaposi’s sarcoma
  • Other Medical Uses: In some cases, vinblastine may be used off-label for other medical conditions or as part of experimental treatments.

How does the Vinblastine Sulphate for Injection USP work?

Vinblastine Sulphate for Injection USP works by disrupting the growth and division of cancer cells, ultimately leading to their destruction. It belongs to a class of drugs known as vinca alkaloids, and its mechanism of action involves interference with microtubules, which are essential components of the cell’s structural framework (cytoskeleton). Here’s how Vinblastine Sulphate works:

  • Microtubules and Cell Division: Microtubules are thin, tubelike structures that play a crucial role in various cellular processes, including cell division. During cell division, microtubules form the mitotic spindle, a structure responsible for segregating chromosomes into daughter cells.
  • Vinblastine’s Action: Vinblastine works by binding to and destabilizing microtubules, preventing them from properly forming the mitotic spindle. In normal cell division, the mitotic spindle ensures the precise separation of chromosomes, allowing for the creation of two identical daughter cells.
  • Disrupted Cell Division: When Vinblastine interferes with microtubules, it disrupts the orderly process of cell division. This disruption leads to several outcomes:
    Inhibited Chromosome Segregation: Vinblastine prevents chromosomes from separating correctly, leading to errors in chromosome distribution.
    Arrested Cell Division: Cancer cells are often rapidly dividing. Vinblastine can arrest these cells at various stages of the cell cycle, preventing them from completing division.
    Cell Death: The inability of cancer cells to divide and reproduce correctly eventually leads to their death.
  • Selective Toxicity: Vinblastine’s mechanism of action primarily affects rapidly dividing cells, such as cancer cells. Normal, healthy cells are also affected, but they can often recover more effectively from the drug’s effects due to their lower rate of division.
  • AntiCancer Effects: By inhibiting microtubule function and disrupting cell division, Vinblastine reduces the growth and proliferation of cancer cells. Over time, this can lead to tumor shrinkage and, in some cases, complete remission of cancer.

It’s important to note that Vinblastine is typically used in combination with other chemotherapy drugs or treatments, as part of a comprehensive cancer treatment plan developed by an oncologist. The specific regimen, dosage, and duration of Vinblastine treatment depend on various factors, including the type and stage of cancer being treated, the patient’s overall health, and the response to therapy.

While Vinblastine can be effective in treating certain types of cancer, it may also cause side effects, and its use should be carefully monitored by healthcare professionals. Common side effects include nausea, vomiting, fatigue, and bone marrow suppression, which can lead to decreased blood cell counts.

Benefits of Vinblastine Sulphate for Injection USP:

  • Cancer Treatment: Vinblastine is primarily used to treat a range of cancers, including Hodgkin’s lymphoma, nonHodgkin’s lymphoma, testicular cancer, breast cancer (in combination with other drugs), certain types of lung cancer, and Kaposi’s sarcoma. Its main benefit is its potential to inhibit the growth and division of cancer cells, leading to tumor shrinkage and, in some cases, remission.
  • Adjunct to Other Therapies: Vinblastine is often used in combination with other chemotherapy drugs or radiation therapy to enhance the effectiveness of cancer treatment. It can be part of a comprehensive treatment plan developed by an oncologist.
  • Blood Disorders: In some cases, Vinblastine may be used to treat certain blood disorders, such as idiopathic thrombocytopenic purpura (ITP), a condition characterized by low platelet counts.

Potential Side Effects of Vinblastine Sulphate for Injection USP:

It’s important to note that not everyone will experience these side effects, and their severity can vary from person to person. Healthcare providers take precautions to manage side effects and provide supportive care during treatment.

  • Bone Marrow Suppression: Vinblastine can affect the bone marrow’s ability to produce blood cells, leading to decreased counts of red blood cells (anemia), white blood cells (leukopenia), and platelets (thrombocytopenia). This can result in fatigue, increased infection risk, and bleeding tendencies.
  • Gastrointestinal Disturbances: Nausea, vomiting, and diarrhea are common gastrointestinal side effects. These symptoms can be managed with antinausea medications.
  • Peripheral Neuropathy: Vinblastine can cause damage to peripheral nerves, leading to symptoms such as numbness, tingling, or weakness in the extremities (hands and feet).
  • Constipation: Some individuals may experience constipation as a side effect.
  • Fatigue: Feeling tired or fatigued is a common side effect of chemotherapy, including Vinblastine.
  • Hair Loss: Hair loss (alopecia) is possible with Vinblastine treatment, although it is generally less severe than with some other chemotherapy drugs.
  • Muscle Weakness: Muscle weakness can occur in some cases.
  • Liver Function: Vinblastine can affect liver function, leading to elevated liver enzymes in blood tests.
  • Injection Site Reactions: Pain, redness, or swelling at the injection site can occur.
  • Allergic Reactions: While rare, allergic reactions to Vinblastine are possible and may include symptoms like rash, itching, or difficulty breathing.

Frequently asked questions about Vinblastine Sulphate for Injection USP

  • What is Vinblastine Sulphate for Injection USP, and how does it work?

Vinblastine is a chemotherapy medication used to treat various types of cancer. It works by disrupting the growth and division of cancer cells.

  • What types of cancer can Vinblastine be used to treat?

Vinblastine is used to treat Hodgkin’s lymphoma, non-Hodgkin’s lymphoma, testicular cancer, breast cancer, certain types of lung cancer, and Kaposi’s sarcoma, among others.

  • How is Vinblastine Sulphate for Injection administered?

It is typically administered intravenously (IV) by a healthcare professional in a clinical setting.

  • Is Vinblastine used alone or in combination with other treatments?

Vinblastine is often used in combination with other chemotherapy drugs or radiation therapy as part of a comprehensive cancer treatment plan.

  • What are the common side effects of Vinblastine treatment?

Common side effects may include bone marrow suppression (leading to anemia, leukopenia, and thrombocytopenia), gastrointestinal disturbances (nausea, vomiting, diarrhea), peripheral neuropathy, fatigue, hair loss, and muscle weakness, among others.

  • How is bone marrow suppression managed during Vinblastine treatment?

Healthcare providers monitor blood cell counts regularly during treatment. Supportive care measures, such as blood transfusions or growth factors, may be used to manage low blood cell counts.

  • Can Vinblastine cause hair loss?

Yes, hair loss (alopecia) is a potential side effect of Vinblastine, although it is generally less severe than with some other chemotherapy drugs.

  • How long is Vinblastine treatment typically administered?

The duration of Vinblastine treatment varies depending on the type and stage of cancer being treated and the patient’s response to therapy. It may be given as a series of cycles over several weeks or months.

  • Are there any precautions or contraindications for Vinblastine treatment?

Vinblastine should not be used during pregnancy, and precautions should be taken to prevent pregnancy during and after treatment. It should also be used with caution in individuals with liver or kidney problems.

  • What should I do if I experience side effects during Vinblastine treatment?

It’s important to report any side effects to your healthcare provider promptly. They can provide guidance on managing side effects and may adjust your treatment plan if necessary.

  • Is it safe to receive other medications or supplements while undergoing Vinblastine treatment?

Inform your healthcare provider about all medications, supplements, and herbal products you are taking to check for potential interactions or contraindications.

  • Can I continue working or daily activities during Vinblastine treatment?

The ability to work and engage in daily activities may be affected by side effects. Discuss any concerns with your healthcare provider, who can provide guidance based on your individual situation.

As Vinblastine Sulphate for Injection USP Exporters; We can cater to export business queries from the following geographies. We are exporting our Vinblastine Sulphate for Injection USP product in the Following Countries-

Russia and CIS Countries: Azerbaijan, Armenia, Belarus, Georgia, Kazakhstan, Kyrgyzstan, Moldova, Russia, Tajikistan, Turkmenistan, Uzbekistan and Ukraine

GCC/ Middle East Countries: Saudi Arabia, Yemen, Oman, Bahrain, UAE, Lebanon, Jordan, and Iraq.

African Countries: Nigeria, Tanzania, Sudan, Zambia, Benin, Angola, Liberia

Southeast Asia: Cambodia, Indonesia, Laos, Malaysia, Myanmar, Philippines, Singapore, Thailand, Vietnam, Brunei Darussalam

Other Asian Countries: Nepal, Myanmar, Malaysia, Cambodia, Bhutan, Sri Lanka, Mauritius

Vinblastine Sulphate for Injection USP Regulatory Documents:

  • Certificate of Analysis (COA)
  • Method of Analysis (MOA)
  • Stability Data (Accelerated stability / Long-term stability / Zone 4b)
  • CTD Dossier / ACTD Dossiers / eCTD Dossiers
  • Certificate of Pharmaceuticals Product (COPP)
  • Free Sale Certificate (FSC)
Contact the most reliable manufacturer of Vinblastine Sulphate for Injection USP, Taj Pharmaceuticals Limited, to get bulk quantities at a reasonable price.

To Place Orders:

Direct line: +91 8448 444 095 / WhatsApp +91 74 0000 9975 / 74 0000 9976
E-Mail: info@tajpharma.com
Toll free: 1-800-222-434 / Toll free: 1-800-222-825
General EPA BX: +91 22 2637 4592 / +91 22 2637 4593
Fax No: +91 22 2634 1274

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