post-title portfolio-title Thioguanine Tablets 40mg 2023-02-24 08:53:12 no no

GENERIC NAME OF THE MEDICINAL PRODUCT:

Thioguanine Tablets 40mg

QUALITATIVE AND QUANTITATIVE COMPOSITION:

Thioguanine Tablets 40mg
Each uncoated tablet contains:
Thioguanine USP……………40mg
Excipients………………………q.s.

THERAPEUTIC INDICATIONS:

Tioguanine also known as 6-thioguanine is a medication used to treat acute myeloid leukemia, acute lymphocytic leukemia, and chronic myeloid leukemia.

CAUTION & WARNING:

Caution: It is dangerous to take this preparation except under medical supervision.
Warning: Cytotoxic Agent: To be supplied against demand from Cancer Hospitals, Institutions and against prescription of a Cancer Specialist only.
This drug is only to be taken under close medical supervision. Do not take in larger doses or more frequently or for a longer time than specifically directed by the physician. Periodic blood counts are necessary to determine proper dose to avoid ill effects.
Dispense in tight container as defines in the USP
Read side panel warning carefully before using
Keep out of reach and sight of children.
Swallow complete tablet, do not crush or chew.

STORAGE & DOSAGE:

Storage: Store protected from moisture at a temperature not exceeding 30°C. Do not refrigerate.
Dosage: As directed by Oncologist.
For Oral use. Read the package insert before use.

Thioguanine Tablets 40mg Technical Specification:

Product Name:Thioguanine Tablets 40mg
Brand Name:Thioguanine
Strength:40mg
Dosage Form:Tablets
Packing:10s, 25s, 30s
Route of Administration:For Oral Use only.
Pack Insert/Leaflet:PIL (Patient Information Leaflet), SmPC (Summary Product Characteristics)
Regulatory Documents:COA, MOA, COPP, FSC, Stability Studies, GMP, CTD Dossier
Therapeutic use:Anti-Cancer
Indication: Tioguanine also known as 6-thioguanine is a medication used to treat acute myeloid leukemia, acute lymphocytic leukemia, and chronic myeloid leukemia.
Storage:Store protected from moisture at a temperature not exceeding 30°C. Do not refrigerate.

GENERIC NAME OF THE MEDICINAL PRODUCT:

  • Thioguanine Tablets 40mg

QUALITATIVE AND QUANTITATIVE COMPOSITION:

  • Thioguanine Tablets 40mg
    Each uncoated tablet contains:
    Thioguanine USP……………40mg
    Excipients………………………q.s.

THERAPEUTIC INDICATIONS:

Tioguanine also known as 6-thioguanine is a medication used to treat acute myeloid leukemia, acute lymphocytic leukemia, and chronic myeloid leukemia.

CAUTION & WARNING:

Caution: It is dangerous to take this preparation except under medical supervision.
Warning: Cytotoxic Agent: To be supplied against demand from Cancer Hospitals, Institutions and against prescription of a Cancer Specialist only.
This drug is only to be taken under close medical supervision. Do not take in larger doses or more frequently or for a longer time than specifically directed by the physician. Periodic blood counts are necessary to determine proper dose to avoid ill effects.
Dispense in tight container as defines in the USP
Read side panel warning carefully before using
Keep out of reach and sight of children.
Swallow complete tablet, do not crush or chew.

STORAGE & DOSAGE:

Storage: Store protected from moisture at a temperature not exceeding 30°C. Do not refrigerate.
Dosage: As directed by the Oncologist.
For Oral use. Read the package insert before use.

Why Taj Pharmaceuticals? 

At Taj Pharmaceuticals, we prioritize your well-being and provide compelling reasons why we are the ideal choice for your healthcare needs when it comes to Thioguanine Tablets. Here’s an in-depth look at why we stand out:

  • Quality Assurance: Our unwavering commitment to quality is at the core of our operations. Thioguanine Tablets, like all our medications, undergo stringent quality control measures. We ensure that each tablet meets the highest industry standards, guaranteeing your safety and therapeutic effectiveness.
  • Safety First: Your safety is paramount to us. We rigorously test and adhere to strict safety protocols to ensure that our products are safe for consumption. Thioguanine Tablets are no exception, and we go the extra mile to provide you with peace of mind regarding their safety and efficacy.
  • Proven Efficacy: Our Thioguanine Tablets are designed for optimal therapeutic efficacy. Through extensive research and development, we have crafted these tablets to effectively address specific medical conditions, ensuring that you receive the maximum benefit from your treatment.
  • Affordability and Accessibility: We understand the importance of accessible healthcare. Taj Pharmaceuticals strives to offer cost-effective solutions, making essential medications like Thioguanine Tablets accessible to patients without compromising quality. Our commitment to affordability ensures that critical treatments are within reach.
  • Global Reach and Distribution: Taj Pharmaceuticals has a global presence, ensuring that patients worldwide have access to Thioguanine Tablets. Our expansive distribution network is designed to reach patients wherever they are, ensuring global healthcare accessibility.
  • Customer-Centric Approach: Your satisfaction is our top priority. We prioritize providing exceptional service and support to create a positive healthcare experience for both healthcare professionals and patients.
  • Environmental Responsibility: We are dedicated to sustainable and environmentally responsible manufacturing practices. We take measures to minimize our ecological footprint and promote sustainability in our operations.

Choosing Taj Pharmaceuticals for Thioguanine Tablets means choosing a reliable healthcare partner. Our commitment to quality, safety, affordability, and customer satisfaction sets us apart, ensuring that your healthcare needs are met with trust and reliability. Your health and well-being are central to our mission.

What are Thioguanine Tablets 40mg and its uses:

Thioguanine Tablets 40mg, also known by its brand name Tabloid, is a medication that contains the active ingredient thioguanine. Thioguanine is classified as an antimetabolite, and it is used primarily in the treatment of certain types of leukemia and related blood disorders. Here’s a closer look at Thioguanine Tablets and their uses:

  • Leukemia Treatment: Thioguanine Tablets are primarily used in the treatment of acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML), particularly in pediatric patients. These conditions involve the abnormal growth and proliferation of white blood cells (leukocytes) in the bone marrow. Thioguanine helps inhibit the growth of these cancerous cells, leading to improved outcomes in leukemia treatment.
  • Blood Disorders: In addition to leukemia, Thioguanine may be used in the management of other blood disorders, such as myelodysplastic syndromes (MDS) and certain types of lymphomas. It can help suppress the overproduction of abnormal blood cells characteristic of these conditions.
  • Off-Label Uses: In some cases, Thioguanine may be prescribed for off-label uses, such as in the treatment of inflammatory bowel disease (IBD) or autoimmune disorders. These uses are less common and typically considered when other treatments have proven ineffective or are not suitable.

It’s essential to note that Thioguanine is a potent medication with potential side effects, and its use should be closely monitored by a healthcare provider experienced in oncology or hematology. The dosage and treatment duration will vary depending on the specific condition being treated and the patient’s individual response to the medication. Thioguanine works by interfering with the DNA and RNA synthesis processes within rapidly dividing cells, including cancer cells. This disruption inhibits the cells’ ability to replicate and grow, ultimately leading to a reduction in the number of cancerous or abnormal cells.

How do Thioguanine Tablets 40mg Work?

Thioguanine Tablets 40mg, containing the active ingredient thioguanine, work by interfering with the normal DNA and RNA synthesis processes within rapidly dividing cells, particularly cancer cells. Thioguanine is classified as an antimetabolite, which means it mimics the structure of certain naturally occurring molecules involved in these processes. Here’s how Thioguanine Tablets work:

  1. Mimicking Purine Bases: Thioguanine is structurally similar to the purine bases adenine and guanine, which are essential components of DNA and RNA. DNA and RNA are the genetic materials of cells and play a crucial role in cell growth, division, and function.
  2. Incorporation into DNA and RNA: When Thioguanine is ingested and metabolized in the body, it is converted into active metabolites. These metabolites can be incorporated into the DNA and RNA molecules during their synthesis.
  3. Disruption of Nucleic Acid Structure: The presence of Thioguanine in DNA and RNA molecules disrupts their normal structure and functioning. This disruption inhibits the ability of DNA and RNA to code for and produce essential proteins and enzymes that are necessary for cell growth and division.
  4. Inhibition of Cell Division: By interfering with DNA and RNA synthesis and, subsequently, protein production, Thioguanine inhibits the normal cell division process. This is particularly effective in rapidly dividing cells, including cancer cells.
  5. Selective Action on Cancer Cells: Thioguanine’s mechanism of action primarily affects rapidly dividing cells, which are characteristic of cancer cells. Healthy cells in the body, which divide at a slower rate, are less affected by the medication.
  6. Cell Death: Inhibition of cell division eventually leads to the death of cancer cells, reducing the overall tumor burden and helping to control or eliminate the cancer.

It’s important to note that Thioguanine is used primarily in the treatment of leukemia and related blood disorders, where the goal is to target and suppress the abnormal growth of cancerous cells in the bone marrow. The medication is administered under the close supervision of an oncologist or hematologist who monitors its effectiveness and manages potential side effects.

Benefits of Thioguanine Tablets 40mg:

The primary benefits of Thioguanine Tablets 40mg are associated with their effectiveness in the treatment of certain types of leukemia and related blood disorders. These benefits include:

  • Leukemia Treatment: Thioguanine Tablets are particularly valuable in the treatment of acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML), especially in pediatric patients. They play a crucial role in suppressing the excessive growth and proliferation of cancerous white blood cells in the bone marrow.
  • Blood Disorder Management: In addition to leukemia, Thioguanine may also be used in the management of other blood disorders, such as myelodysplastic syndromes (MDS) and certain types of lymphomas. By regulating the production of abnormal blood cells, it helps address the underlying causes of these conditions.
  • Improved Quality of Life: Thioguanine treatment can lead to the remission of leukemia and related disorders, offering patients a significantly improved quality of life. Symptoms such as fatigue, weakness, and susceptibility to infections can be alleviated as cancer cells are controlled.
  • Prolonged Survival: For many patients, Thioguanine can extend their lifespan by effectively managing leukemia and related blood disorders. The treatment aims to keep the disease in check, allowing patients to lead longer and healthier lives.
  • Reduced Risk of Complications: By suppressing the abnormal growth of cancerous cells in the bone marrow, Thioguanine reduces the risk of complications associated with leukemia, such as bleeding, anemia, and severe infections.
  • Potential for Curative Treatment: In some cases, Thioguanine may be a crucial component of a curative treatment regimen. Achieving complete remission of leukemia or related disorders is the goal for many patients, and Thioguanine contributes to this objective.

It’s important to note that the use of Thioguanine Tablets 40mg should be carefully supervised by a healthcare provider with expertise in oncology or hematology. The dosage and duration of treatment are individualized based on the specific diagnosis, the patient’s age and health status, and the response to the medication.

Common Side Effects of Thioguanine Tablets 40mg:

  • Bone Marrow Suppression: One of the most significant side effects of Thioguanine is bone marrow suppression, which can lead to a decrease in the production of red blood cells, white blood cells, and platelets. This may result in anemia, increased susceptibility to infections, and an increased risk of bleeding.
  • Gastrointestinal Symptoms: Patients may experience gastrointestinal side effects such as nausea, vomiting, diarrhea, and abdominal pain. These symptoms are usually mild and can be managed with supportive care.
  • Hepatic Toxicity: Thioguanine can affect liver function and may lead to elevated liver enzyme levels. Regular monitoring of liver function is essential during treatment.
  • Pancreatitis: In rare cases, Thioguanine can cause inflammation of the pancreas (pancreatitis), leading to abdominal pain and other symptoms.
  • Skin Reactions: Skin rashes and itching may occur as a side effect of Thioguanine treatment.
  • Increased Risk of Infection: Due to bone marrow suppression, patients taking Thioguanine may be more susceptible to infections. Prompt medical attention is required if signs of infection, such as fever, occur.
  • Hair Loss: Hair loss (alopecia) is a potential side effect but is usually temporary and reversible.
  • Hypersensitivity Reactions: Although rare, hypersensitivity reactions to Thioguanine can occur and may manifest as fever, rash, or other allergic symptoms.

It’s crucial to understand that Thioguanine is a potent medication that should be used under the close supervision of an oncologist or hematologist experienced in its use. The dosage and treatment duration are tailored to each patient’s specific condition and response to the medication. Regular blood tests and medical check-ups are necessary to monitor for side effects and treatment efficacy. Patients should report any unusual or severe side effects to their healthcare provider promptly. The use of Thioguanine Tablets involves weighing the potential benefits of cancer treatment against the risk of side effects, and this decision is made on an individual basis in consultation with a medical professional.

Frequently Asked Questions About Thioguanine Tablets 40mg:

Certainly, here are some frequently asked questions (FAQs) about Thioguanine Tablets 40mg:

  • What are Thioguanine Tablets 40mg?

Thioguanine Tablets 40mg contain the active ingredient thioguanine and are used primarily in the treatment of leukemia, particularly acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML), as well as related blood disorders.

  • How does Thioguanine work in treating leukemia?

Thioguanine interferes with the DNA and RNA synthesis processes in rapidly dividing cells, including cancer cells. This disruption inhibits their ability to replicate and grow, ultimately leading to a reduction in the number of cancerous cells.

  • What conditions are Thioguanine Tablets used to treat?

Thioguanine Tablets are primarily used to treat leukemia, including ALL and AML, and may also be used in the management of myelodysplastic syndromes (MDS) and certain lymphomas.

  • Are there any common side effects of Thioguanine Tablets?

Yes, common side effects may include bone marrow suppression (leading to anemia, increased infection risk, and bleeding), gastrointestinal symptoms (nausea, vomiting, diarrhea, abdominal pain), liver function changes, pancreatitis, skin rashes, and hypersensitivity reactions.

  • How is the dosage of Thioguanine determined?

The dosage of Thioguanine is individualized based on factors such as the specific diagnosis, the patient’s age and overall health, and the response to treatment. A healthcare provider with expertise in oncology or hematology will determine the appropriate dosage.

  • What precautions should I take while taking Thioguanine Tablets?

Patients taking Thioguanine should be closely monitored by a healthcare provider. Regular blood tests and medical checkups are essential to assess treatment efficacy and safety. Inform your healthcare provider of any side effects or concerns promptly.

  • Can Thioguanine be used during pregnancy or breastfeeding?

Thioguanine is generally not recommended during pregnancy, especially in the first trimester, and should be used with caution while breastfeeding. Consult with your healthcare provider for guidance if you are pregnant or nursing.

  • Are there any drug interactions with Thioguanine?

Yes, Thioguanine may interact with other medications. Inform your healthcare provider about all the medications, supplements, and herbal products you are taking to avoid potential interactions.

  • Is Thioguanine a curative treatment for leukemia?

Thioguanine is an important component of leukemia treatment regimens and can contribute to achieving complete remission. However, whether it leads to a cure depends on various factors, including the specific type and stage of leukemia and the patient’s response to treatment.

  • How long will I need to take Thioguanine Tablets?

The duration of Thioguanine treatment varies depending on the specific condition being treated and the patient’s response. It may be taken for an extended period, and the treatment plan will be determined by your healthcare provider.

As Thioguanine Tablets Exporters; We can cater to export business queries from the following geographies. We are exporting our Thioguanine Tablets product in the Following Countries-

Russia and CIS Countries: Azerbaijan, Armenia, Belarus, Georgia, Kazakhstan, Kyrgyzstan, Moldova, Russia, Tajikistan, Turkmenistan, Uzbekistan and Ukraine

GCC/ Middle East Countries: Saudi Arabia, Yemen, Oman, Bahrain, UAE, Lebanon, Jordan, and Iraq.

African Countries: Nigeria, Tanzania, Sudan, Zambia, Benin, Angola, Liberia

Southeast Asia: Cambodia, Indonesia, Laos, Malaysia, Myanmar, Philippines, Singapore, Thailand, Vietnam, Brunei Darussalam

Other Asian Countries: Nepal, Myanmar, Malaysia, Cambodia, Bhutan, Sri Lanka, Mauritius

Thioguanine Tablets Regulatory Documents:

  • Certificate of Analysis (COA)
  • Method of Analysis (MOA)
  • Stability Data (Accelerated stability / Long-term stability / Zone 4b)
  • CTD Dossier / ACTD Dossiers / eCTD Dossiers
  • Certificate of Pharmaceuticals Product (COPP)
  • Free Sale Certificate (FSC)
Contact the most reliable manufacturer of Thioguanine Tablets, Taj Pharmaceuticals Limited, to get bulk quantities at a reasonable price.

To Place Orders:

Direct line: +91 8448 444 095 / WhatsApp +91 74 0000 9975 / 74 0000 9976
E-Mail: info@tajpharma.com
Toll free: 1-800-222-434 / Toll free: 1-800-222-825
General EPA BX: +91 22 2637 4592 / +91 22 2637 4593
Fax No: +91 22 2634 1274

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