GENERIC NAME OF MEDICINAL PRODUCT:

A. Streptokinase Injection BP (15,00,000IU)
B. Streptokinase Injection BP (7,50,000IU)

QUALITATIVE AND QUANTITATIVE COMPOSITION:

A. Streptokinase Injection BP (15,00,000IU)
 Composition:
Each vial contains:
Streptokinase BP ………………………15,00,000IU
Excipients…………………………………q.s.
B. Streptokinase Injection BP (7,50,000IU)
 Composition:
Each vial contains:
Streptokinase BP ………………………7,50,000IU
Excipients…………………………………q.s.


THERAPEUTIC INDICATIONS:

Acute Evolving Myocardial Infarction
Acute Massive Pulmonary Embolism
Deep Vein Thrombosis
Arterial Thrombosis or Embolism
Arteriovenous Cannulae Occlusion. 

DIRECTION OF USE:

For IV infusion only.

CAUTION & WARNING:

CAUTION: If any foreign particle is visible in the vial after reconstitution, please do not use the solution.
FLIP-OFF SEAL IS PROVIDED FOR TAMPER EVIDENCE
WARNING: Not to be sold by retail without the prescription of a Registered Medical Practitioner only.

STORAGE & DOSAGE:

Storage: Store the vial in original carton at 2° to 8°C. Use reconstituted preparation within 24 hours.
Keep all medicines out of reach of children.
Dosage: As directed by Physician.

Streptokinase Injection BP 7,50,000IU Technical Specification:

Product Name:Streptokinase Injection BP
Brand Name:Generic
Strength:15,00,000IU, 7,50,000IU
Dosage Form:Lyophilized
Dry Powder Injection (Sterile) *Preservative Free
Packing:1 Vial + 1 Ampule + WFI Tray
Route of Administration:For IV infusion only
Pack Insert/Leaflet:PIL (Patient Information Leaflet), SmPC (Summary Product Characteristics)
Regulatory Documents:COA, MOA, COPP, FSC, Stability Studies, GMP, CTD Dossier
Therapeutic use:Thrombolytic Agent
Indication: Acute Evolving Myocardial Infarction,  Acute Massive Pulmonary Embolism, Deep Vein Thrombosis, Arterial Thrombosis or Embolism, Arteriovenous Cannulae Occlusion
Storage:Store the vial in the original carton at 2° to 8°C. Use reconstituted preparation within 24 hours.

GENERIC NAME OF MEDICINAL PRODUCT:

  • Streptokinase Injection BP (7,50,000IU)

QUALITATIVE AND QUANTITATIVE COMPOSITION:

  • Streptokinase Injection BP (7,50,000IU)
    Composition:
    Each vial contains:
    Streptokinase BP ………………………7,50,000IU
    Excipients…………………………………q.s.

THERAPEUTIC INDICATIONS:

  • Acute Evolving Myocardial Infarction
  • Acute Massive Pulmonary Embolism
  • Deep Vein Thrombosis
  • Arterial Thrombosis or Embolism
  • Arteriovenous Cannulae Occlusion.

DIRECTION OF USE:

For IV infusion only.

CAUTION & WARNING:

CAUTION: If any foreign particle is visible in the vial after reconstitution, please do not use the solution.

FLIP-OFF SEAL IS PROVIDED FOR TAMPER EVIDENCE

WARNING:  Not to be sold by retail without the prescription of a Registered Medical Practitioner only.

STORAGE & DOSAGE:

Storage: Store the vial in the original carton at 2° to 8°C. Use reconstituted preparation within 24 hours.

Keep all medicines out of reach of children.

Dosage: As directed by the Physician.

Why Taj Pharmaceuticals?

Taj Pharma stands out as the ideal choice for Streptokinase Injection BP for several compelling reasons. With a rich legacy of pharmaceutical excellence, Taj Pharma has earned a reputation for delivering top-quality healthcare solutions. Our commitment to uncompromising quality assurance and rigorous manufacturing standards ensures that every Streptokinase Injection BP we produce meets the highest industry standards. Furthermore, Taj Pharma boasts a global presence and an extensive network of partners, making our products readily available to healthcare providers and patients worldwide. We understand the critical importance of timely and reliable access to life-saving medications, and we take pride in our ability to meet these urgent needs.

At Taj Pharma, we prioritize patient well-being and safety above all else. Our Streptokinase Injection BP is meticulously tested and manufactured to ensure efficacy and safety in treating conditions such as acute myocardial infarction. By choosing Taj Pharma, you’re not just getting a pharmaceutical product; you’re gaining a trusted partner in healthcare, dedicated to improving and saving lives. In conclusion, when it comes to Streptokinase Injection BP, Taj Pharma stands as the industry leader, offering quality, accessibility, and a commitment to patients’ health. Partner with us, and experience the difference in healthcare excellence that Taj Pharma brings to the table.

What is Streptokinase Injection BP and its use?

Streptokinase Injection BP is a medication used in the treatment of various medical conditions, primarily for its thrombolytic or clotdissolving properties. Here is some key information about Streptokinase Injection BP and its uses:

  • Composition: Streptokinase is a naturally occurring enzyme produced by certain strains of streptococcal bacteria. In Streptokinase Injection BP, this enzyme is formulated for medical use.
  • Thrombolytic Action: Streptokinase works by promoting the breakdown of blood clots (thrombi) that can form in blood vessels. It activates the body’s own natural clotdissolving system, which can help restore blood flow in blocked arteries and veins.
  • Medical Uses: Streptokinase Injection BP is primarily used in emergency medical situations to treat conditions related to blood clot formation. Some common medical uses include:
  • Acute Myocardial Infarction (Heart Attack): Streptokinase is administered to dissolve blood clots that block blood flow to the heart muscle during a heart attack, helping to restore blood flow and minimize heart damage.
  • Pulmonary Embolism: It is used to dissolve blood clots that have traveled to the lungs, causing a pulmonary embolism, which can be lifethreatening.
  • Deep Vein Thrombosis (DVT): Streptokinase can be used in the treatment of DVT, a condition where blood clots form in deep veins, often in the legs.
  • Arterial Occlusion: It may also be employed to treat arterial occlusions, where blood flow is blocked in arteries, potentially leading to tissue damage.
  • Administration: Streptokinase is typically administered intravenously by healthcare professionals in a hospital setting. The dosage and duration of treatment will vary depending on the specific medical condition being treated.
  • Precautions: Streptokinase therapy requires careful monitoring by healthcare providers due to the risk of bleeding, which can be a side effect of the medication. Patients with a history of bleeding disorders or recent surgery may not be suitable candidates for Streptokinase treatment.
  • Contraindications: There are certain contraindications for the use of Streptokinase, such as a history of stroke, recent trauma or surgery, uncontrolled high blood pressure, and active bleeding disorders.

Patients should always consult with their healthcare provider to determine if Streptokinase Injection BP is an appropriate treatment option for their specific medical condition, and it should only be administered under medical supervision. The use of this medication can be lifesaving in certain emergency situations, but it requires careful assessment and monitoring to ensure its safety and effectiveness.

How does Streptokinase Injection BP work?

Streptokinase Injection BP works by utilizing the enzymatic activity of streptokinase to break down blood clots or thrombi that may have formed within the blood vessels. Here’s how it works:

  • Clot Formation: Blood clots, also known as thrombi, can form inside blood vessels due to various reasons, such as injury to the blood vessel lining, the presence of atherosclerotic plaques (cholesterol deposits), or other factors. These clots can obstruct blood flow in the affected vessel.
  • Fibrin Formation: When a blood clot forms, it consists of a mesh of a protein called fibrin, along with platelets and red blood cells. Fibrin is responsible for holding the clot together.
  • Thrombolytic Action: Streptokinase, the active ingredient in Streptokinase Injection BP, has the remarkable ability to activate the body’s natural clot-dissolving system. Specifically, it converts plasminogen, an inactive precursor enzyme in the blood, into plasmin, an active enzyme that can break down fibrin.
  • Fibrinolysis: Plasmin, once generated by streptokinase, works to break down the fibrin mesh within the blood clot. This enzymatic process cleaves the fibrin strands, gradually dissolving the clot into smaller fragments.
  • Restoring Blood Flow: As the clot dissolves, it allows the blood to flow more freely through the affected blood vessel. This can be crucial in medical conditions where a clot is blocking blood flow, such as in cases of acute myocardial infarction (heart attack), pulmonary embolism, deep vein thrombosis, or arterial occlusions.
  • Improved Oxygen Supply: By dissolving the clot and restoring blood flow, Streptokinase Injection BP helps improve the supply of oxygen and nutrients to the tissues and organs downstream from the blocked vessel, preventing tissue damage and potentially saving lives.

Benefits of Streptokinase Injection BP:

  • Clot Dissolution: The primary benefit of Streptokinase Injection BP is its ability to effectively dissolve blood clots. This can be crucial in emergency situations where blood clots are obstructing blood flow to vital organs or tissues.
  • Life-Saving: In conditions like acute myocardial infarction (heart attack), pulmonary embolism, deep vein thrombosis (DVT), or arterial occlusions, prompt administration of Streptokinase can save lives by restoring blood flow and preventing further tissue damage.
  • Minimizes Organ Damage: By dissolving clots and restoring blood flow, Streptokinase can help minimize organ damage and improve the chances of recovery in patients suffering from clot-related conditions.
  • Accessibility: Streptokinase Injection BP is relatively affordable and widely available, making it accessible in many healthcare settings around the world.

Side Effects and Risks of Streptokinase Injection BP:

  • Bleeding: The most significant risk associated with Streptokinase is bleeding. Because it promotes the dissolution of blood clots, it can also lead to bleeding in other parts of the body. This risk is carefully assessed before administering the medication, and healthcare providers closely monitor patients during treatment.
  • Allergic Reactions: Some individuals may be allergic to Streptokinase or components of the injection. Allergic reactions can range from mild skin rashes to severe anaphylactic reactions, which are potentially life-threatening.
  • Hypo tension: A drop in blood pressure (hypo tension) can occur as a side effect of Streptokinase treatment. It is monitored and managed by healthcare professionals during administration.
  • Fever and Chills: Some patients may experience fever and chills as a reaction to Streptokinase.
  • Nausea and Vomiting: Nausea and vomiting are possible side effects, though they are generally mild.
  • Re perfusion Injury: In some cases, when blood flow is rapidly restored to an ischemic (oxygen-deprived) tissue, it can cause reperfusion injury, which may manifest as tissue damage or dysfunction.
  • Other Side Effects: Rarely, other side effects such as headache, dizziness, and shortness of breath may occur.

It’s crucial for healthcare providers to carefully assess patients for the risks and benefits of Streptokinase Injection BP before administering it. The decision to use this medication is typically made in emergency situations where the potential benefits of clot dissolution outweigh the potential risks. Close monitoring and appropriate medical management are essential during treatment to minimize complications. Patients should discuss any concerns or side effects with their healthcare provider.

Frequently Asked Questions about Streptokinase Injection BP

Certainly, here are some frequently asked questions (FAQs) about Streptokinase Injection BP along with their answers:

  1. What is Streptokinase Injection BP used for?

Streptokinase Injection BP is used to dissolve blood clots in emergency medical situations. It is commonly used in conditions like acute myocardial infarction (heart attack), pulmonary embolism, deep vein thrombosis (DVT), and arterial occlusions.

  1. How does Streptokinase Injection BP work?

Streptokinase activates the body’s natural clot dissolving system by converting plasminogen into plasmin, an enzyme that breaks down fibrin in blood clots. This process helps dissolve the clot and restore blood flow.

  1. Is Streptokinase Injection BP safe to use?

While Streptokinase can be lifesaving, it also carries risks, primarily the risk of bleeding. Its use should be carefully considered by healthcare professionals in emergency situations, weighing the potential benefits against the risks.

  1. What are the potential side effects of Streptokinase Injection BP?

Common side effects include bleeding, allergic reactions, hypotension, fever, chills, nausea, vomiting, and, rarely, reperfusion injury. Patients should be closely monitored during treatment.

  1. Can anyone receive Streptokinase Injection BP?

Not everyone is a suitable candidate for Streptokinase treatment. Patients with a history of bleeding disorders, recent surgery, uncontrolled high blood pressure, or contraindications may not be eligible.

  1. How is Streptokinase Injection BP administered?

Streptokinase is typically administered intravenously by healthcare professionals in a hospital or emergency setting. The dosage and duration of treatment vary depending on the specific condition being treated.

  1. Are there alternatives to Streptokinase for clot dissolution?

Yes, there are other thrombolytic agents like alteplase and tenecteplase that can be used for clot dissolution, but the choice depends on the patient’s condition and medical history.

  1. How quickly should Streptokinase be administered in a heart attack?

In the case of a heart attack, Streptokinase is most effective when administered as early as possible, ideally within the first few hours after symptoms begin. Prompt treatment can help preserve heart muscle and improve outcomes.

  1. What should I do if I experience side effects while receiving Streptokinase?

If you experience any side effects, inform your healthcare provider immediately. They will assess your condition and may adjust your treatment or provide necessary interventions.

  1. Can Streptokinase be used in pregnant or breastfeeding women?

The use of Streptokinase in pregnant or breastfeeding women should be carefully considered by healthcare providers, weighing the potential risks and benefits on a case by case basis.

As Streptokinase Injection BP Exporters; We can cater to export business queries from the following geographies. We are exporting our Streptokinase Injection BP product in the Following Countries-

Russia and CIS Countries: Azerbaijan, Armenia, Belarus, Georgia, Kazakhstan, Kyrgyzstan, Moldova, Russia, Tajikistan, Turkmenistan, Uzbekistan and Ukraine

GCC/ Middle East Countries: Saudi Arabia, Yemen, Oman, Bahrain, UAE, Lebanon, Jordan, and Iraq.

African Countries: Nigeria, Tanzania, Sudan, Zambia, Benin, Angola, Liberia

Southeast Asia: Cambodia, Indonesia, Laos, Malaysia, Myanmar, Philippines, Singapore, Thailand, Vietnam, Brunei Darussalam

Other Asian Countries: Nepal, Myanmar, Malaysia, Cambodia, Bhutan, Sri Lanka, Mauritius

Streptokinase Injection BP Regulatory Documents:

  • Certificate of Analysis (COA)
  • Method of Analysis (MOA)
  • Stability Data (Accelerated stability / Long-term stability / Zone 4b)
  • CTD Dossier / ACTD Dossiers / eCTD Dossiers
  • Certificate of Pharmaceuticals Product (COPP)
  • Free Sale Certificate (FSC)
Contact the most reliable manufacturer of Streptokinase Injection BP, Taj Pharmaceuticals Limited, to get bulk quantities at a reasonable price.

To Place Orders:

Direct line: +91 8448 444 095 / WhatsApp +91 74 0000 9975 / 74 0000 9976
E-Mail: info@tajpharma.com 
Toll free: 1-800-222-434 / Toll free: 1-800-222-825
General EPA BX: +91 22 2637 4592 / +91 22 2637 4593
Fax No: +91 22 2634 1274