GENERIC NAME OF MEDICINAL PRODUCT:

a) Sevoflurane Liquid for Inhalation USP 250ml

QUALITATIVE AND QUANTITATIVE COMPOSITION:

Sevoflurane Liquid for Inhalation USP 250ml
Each bottle contains:
Sevoflurane USP………………250mg
Excipients………………………q.s.

THERAPEUTIC INDICATION:

Sevoflurane is indicated for induction and maintenance of general anaesthesia in adult and paediatric patients for inpatient and outpatient surgery.

CAUTION & WARNING:

CAUTION: NON-FLAMMABLE
NON-EXPLOSIVE
Inhalation Anasthetic.
Warning: Not to be sold by retail without the prescription of registered Medical Practitioner.

STORAGE & DOSAGE:

Storage: Do not store above 25°C. Do not refrigerate. Keep cap tightly closed.
Keep medicine out of reach of children.
Dosage: As directed by Physician

Sevoflurane Liquid for Inhalation USP 250ml Technical Specification:

Product Name:Sevoflurane Liquid for Inhalation USP
Brand Name:Generics
Strength:250ml
Dosage Form:Liquid
Packing:100ml, 250ml, 500ml
Route of Administration:By Inhalation
Pack Insert/Leaflet:PIL (Patient Information Leaflet), SmPC (Summary Product Characteristics)
Regulatory Documents:COA, MOA, COPP, FSC, Stability Studies, GMP, CTD Dossier
Therapeutic use:Anaesthetics agent
Indication: Sevoflurane is indicated for induction and maintenance of general anaesthesia in adult and paediatric patients for inpatient and outpatient surgery.
Storage:Do not store above 25°C. Do not refrigerate. Keep cap tightly closed.

GENERIC NAME OF MEDICINAL PRODUCT:

  1. Sevoflurane Liquid for Inhalation USP 250ml

QUALITATIVE AND QUANTITATIVE COMPOSITION:

  1. Sevoflurane Liquid for Inhalation USP 250ml
    Each bottle contains:
    Sevoflurane USP………………250mg
    Excipients………………………q.s.

THERAPEUTIC INDICATION:

Sevoflurane is indicated for induction and maintenance of general anaesthesia in adult and paediatric patients for inpatient and outpatient surgery.

CAUTION & WARNING:


CAUTION:
NON-FLAMMABLE
NON-EXPLOSIVE
Inhalation Anesthetic.
Warning: Not to be sold by retail without the prescription of registered Medical Practitioner.

STORAGE & DOSAGE:

Storage: Do not store above 25°C. Do not refrigerate. Keep cap tightly closed.

Keep medicine out of reach of children.

Dosage: As directed by Physician

Why Taj Pharmaceuticals?

Taj Pharma’s Sevoflurane Liquid for Inhalation USP is a vital pharmaceutical offering that plays a crucial role in modern anesthesia. This product is synonymous with safety, precision, and effectiveness, making it an essential tool for healthcare providers. Sevoflurane, the active ingredient, is a highly regarded inhalation anesthetic known for its rapid onset and offset of action, allowing for smoother transitions in and out of anesthesia. This pharmaceutical innovation from Taj Pharma is meticulously manufactured to meet stringent quality standards, ensuring that patients receive the highest level of care during surgical procedures. Medical professionals trust Sevoflurane Liquid for Inhalation USP for its consistent and predictable performance, helping them maintain precise control over anesthesia levels throughout surgeries of various durations and complexities. Patients benefit from the convenience and reliability of Sevoflurane, which minimizes post-operative recovery time and side effects. The liquid formulation ensures accurate dosing and efficient vaporization, contributing to a safer and more comfortable anesthesia experience. When it comes to anesthesia, quality and precision are non-negotiable, and Taj Pharma’s Sevoflurane Liquid for Inhalation USP delivers on both fronts. Whether you’re a healthcare provider seeking a trusted anesthetic solution or a patient looking for the best possible care, Taj Pharma’s commitment to excellence ensures that you’re in capable hands.

What is Sevoflurane Liquid for Inhalation USP and its Use?

Sevoflurane Liquid for Inhalation USP is a pharmaceutical product used as an inhalation anesthetic during surgical procedures. It is a volatile liquid that, when vaporized, can be inhaled by the patient to induce and maintain general anesthesia. This medication is known for its rapid onset and offset of action, making it a popular choice among anesthetics for both adults and children.

Here are some key points about Sevoflurane Liquid for Inhalation USP and its uses:

  • Anesthetic Properties: Sevoflurane is classified as a halogenated inhalation anesthetic. It acts on the central nervous system to induce a state of unconsciousness, pain relief, and muscle relaxation, allowing surgical procedures to be performed without the patient experiencing pain or discomfort.
  • Quick Onset and Offset: One of the advantages of Sevoflurane is its ability to induce anesthesia rapidly and to allow for a smooth and quick emergence from anesthesia. This makes it suitable for a wide range of surgical procedures, including those of varying duration and complexity.
  • Pediatric Use: Sevoflurane is often preferred for pediatric patients due to its pleasant odor and ease of administration. It is used in a variety of pediatric surgeries, including dental procedures, ear, nose, and throat surgeries, and more.
  • Precise Dosing: Sevoflurane Liquid for Inhalation USP is available in a liquid form that allows for accurate dosing and control over the concentration of the anesthetic gas administered to the patient. This precision is crucial in tailoring anesthesia to individual patient needs.
  • Safety: Sevoflurane is generally considered safe when administered by trained healthcare professionals in a controlled medical environment. However, like all anesthetics, it carries certain risks and side effects, which should be discussed with the medical team before surgery.
  • Post-operative Recovery: Due to its favorable pharmacokinetic profile, patients typically recover relatively quickly from anesthesia with Sevoflurane, which can contribute to shorter post-operative recovery times and reduced side effects.

The use of Sevoflurane Liquid for Inhalation USP should always be guided by medical professionals with expertise in anesthesia. It is essential for patients to have a thorough pre-operative evaluation and discussion with their healthcare team to ensure safe and effective anesthesia during surgery.

How does Sevoflurane Liquid for Inhalation USP Work?

Sevoflurane Liquid for Inhalation USP is an inhalation anesthetic that works by depressing the central nervous system, leading to a state of general anesthesia. Here’s how it works:

  • Inhalation: Sevoflurane is administered to the patient as a vapor via inhalation. It is typically delivered through a specialized anesthesia machine, which precisely controls the concentration of the anesthetic gas being administered.
  • Rapid Distribution: When the patient inhales sevoflurane, it quickly enters the bloodstream through the lungs. This rapid distribution is one of the characteristics that make sevoflurane desirable for anesthesia because it induces anesthesia quickly.
  • Effect on the Brain: Sevoflurane primarily acts on the brain by interacting with various receptors and neurotransmitter systems. It enhances the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) and reduces the activity of excitatory neurotransmitters, leading to a decrease in neuronal activity. This results in the following effects:
  • Unconsciousness: Sevoflurane induces a state of unconsciousness, meaning the patient is not aware of their surroundings and does not feel pain during surgery.
  • Analgesia (Pain Relief): Sevoflurane provides pain relief by dampening the perception of pain signals in the brain.
  • Muscle Relaxation: It causes muscle relaxation, which is essential for surgical procedures as it prevents muscle contractions that could interfere with surgery.
  • Amnesia: Sevoflurane often induces temporary amnesia, so patients typically do not remember the surgical experience.
  • Control and Monitoring: Anesthesia providers carefully monitor the concentration of sevoflurane throughout the procedure to maintain the desired level of anesthesia. This control allows them to adjust the depth of anesthesia as needed to ensure the patient’s safety and comfort.
  • Emergence from Anesthesia: One of the advantages of sevoflurane is its relatively quick offset of action. When the administration of sevoflurane is stopped, the patient typically starts to wake up and regain consciousness relatively rapidly. This allows for a smoother and faster emergence from anesthesia compared to some other anesthetic agents.

It’s important to note that the use of Sevoflurane Liquid for Inhalation USP should be carried out by trained anesthesia professionals in a controlled medical environment to ensure the safety and well-being of the patient. The dosage and administration are carefully tailored to the patient’s specific needs and the requirements of the surgical procedure.

Benefits and Side Effects of Sevoflurane Liquid for Inhalation USP:

Sevoflurane Liquid for Inhalation USP is a commonly used inhalation anesthetic in medical settings. Like any medication, it has both benefits and potential side effects. The benefits include:

Benefits:

  • Rapid Onset and Offset: Sevoflurane is known for its quick induction and emergence from anesthesia. This means patients can be anesthetized and awakened relatively swiftly, reducing post-operative recovery times.
  • Precise Control: Anesthesia providers can precisely control the concentration of sevoflurane during surgery, tailoring the depth of anesthesia to the patient’s specific needs. This control helps maintain a stable anesthetic state throughout the procedure.
  • Reduced Airway Irritation: Sevoflurane is often chosen for its relatively low airway irritation. It is considered to be a gentle anesthetic, making it suitable for a wide range of patients, including pediatric and geriatric populations.
  • Stable Hemodynamics: Sevoflurane is associated with stable cardiovascular function, which is important during surgery to maintain blood pressure and heart rate within acceptable ranges.
  • Suitable for Various Procedures: Sevoflurane can be used for a wide range of surgical procedures, from minor outpatient surgeries to major surgeries that require longer periods of anesthesia.

Side Effects:

  • Respiratory Depression: Sevoflurane, like other anesthetics, can lead to respiratory depression, causing a decrease in the rate and depth of breathing. This is closely monitored during surgery to ensure adequate oxygenation.
  • Hypotension: Sevoflurane can cause a drop in blood pressure, which is carefully managed by anesthesia providers to maintain adequate perfusion to vital organs.
  • Nausea and Vomiting: Post-operative nausea and vomiting (PONV) can occur after surgery, although sevoflurane is considered to have a lower risk of PONV compared to some other anesthetics.
  • Headache and Fatigue: Some patients may experience post-operative headache and fatigue as they emerge from anesthesia, although these symptoms are typically temporary.
  • Liver and Kidney Effects: Prolonged exposure to sevoflurane, particularly in high concentrations, may affect liver and kidney function, so it’s important to use the anesthetic judiciously.
  • Allergic Reactions: While rare, allergic reactions to sevoflurane can occur, leading to skin rashes, itching, or respiratory symptoms.

It’s essential for patients to have a thorough pre-operative evaluation and discussion with their healthcare team to assess the risks and benefits of anesthesia with Sevoflurane Liquid for Inhalation USP. Anesthesia providers carefully monitor patients during surgery to mitigate potential side effects and ensure a safe and comfortable surgical experience.

Frequently Asked Questions for Sevoflurane Liquid for Inhalation USP:

Certainly, here are some frequently asked questions (FAQs) related to Sevoflurane Liquid for Inhalation USP:

  1. What is Sevoflurane Liquid for Inhalation USP used for?

Sevoflurane is used as an inhalation anesthetic during surgical procedures to induce and maintain general anesthesia. It allows patients to be unconscious and painfree during surgery.

  1. How does Sevoflurane work?

Sevoflurane depresses the central nervous system, leading to unconsciousness, pain relief, muscle relaxation, and amnesia. It is administered as a vapor via inhalation.

  1. Is Sevoflurane suitable for all types of surgeries?

Sevoflurane is suitable for a wide range of surgical procedures, including both minor and major surgeries. It is often preferred for its rapid onset and offset of action.

  1. Are there any specific precautions or contraindications for using Sevoflurane?

Patients with certain medical conditions or allergies may not be suitable candidates for Sevoflurane. It’s important to discuss your medical history and allergies with your healthcare team before anesthesia.

  1. What are the potential side effects of Sevoflurane?

Common side effects may include respiratory depression, hypo tension (low blood pressure), nausea, vomiting, and postoperative headache. Your anesthesia provider will monitor and manage these during surgery.

  1. How is the dosage of Sevoflurane determined during surgery?

Anesthesia providers carefully monitor the concentration of Sevoflurane throughout the procedure to maintain the desired depth of anesthesia. The dosage is adjusted based on the patient’s response and the surgical requirements.

  1. How long does it take to wake up after receiving Sevoflurane anesthesia?

The time it takes to wake up after Sevoflurane anesthesia can vary depending on the duration of the surgery and individual factors. However, Sevoflurane is known for its relatively quick emergence from anesthesia.

  1. Is Sevoflurane safe for pediatric patients?

Sevoflurane is commonly used in pediatric anesthesia due to its pleasant odor, ease of administration, and rapid onset/offset characteristics. It is considered safe and effective for children.

  1. Are there any alternatives to Sevoflurane for anesthesia?

Yes, there are various other inhalation anesthetics and intravenous anesthetics available. The choice of anesthesia depends on the patient’s medical condition, the type of surgery, and the preferences of the anesthesia team.

  1. How should I prepare for surgery involving Sevoflurane anesthesia?

Preoperative preparation involves discussing your medical history, allergies, and medications with your healthcare team. You may also be instructed about fasting requirements before surgery.

As Sevoflurane Liquid for Inhalation USP Exporters; We can cater to export business queries from the following geographies. We are exporting our Sevoflurane Liquid for Inhalation USP product in the Following Countries-

Russia and CIS Countries: Azerbaijan, Armenia, Belarus, Georgia, Kazakhstan, Kyrgyzstan, Moldova, Russia, Tajikistan, Turkmenistan, Uzbekistan and Ukraine

GCC/ Middle East Countries: Saudi Arabia, Yemen, Oman, Bahrain, UAE, Lebanon, Jordan, and Iraq.

African Countries: Nigeria, Tanzania, Sudan, Zambia, Benin, Angola, Liberia

Southeast Asia: Cambodia, Indonesia, Laos, Malaysia, Myanmar, Philippines, Singapore, Thailand, Vietnam, Brunei Darussalam

Other Asian Countries: Nepal, Myanmar, Malaysia, Cambodia, Bhutan, Sri Lanka, Mauritius

Sevoflurane Liquid for Inhalation USP Regulatory Documents:

  • Certificate of Analysis (COA)
  • Method of Analysis (MOA)
  • Stability Data (Accelerated stability / Long-term stability / Zone 4b)
  • CTD Dossier / ACTD Dossiers / eCTD Dossiers
  • Certificate of Pharmaceuticals Product (COPP)
  • Free Sale Certificate (FSC)
Contact the most reliable manufacturer of Sevoflurane Liquid for Inhalation USP, Taj Pharmaceuticals Limited, to get bulk quantities at a reasonable price.

To Place Orders:

Direct line: +91 8448 444 095 / WhatsApp +91 74 0000 9975 / 74 0000 9976
E-Mail: info@tajpharma.com 
Toll free: 1-800-222-434 / Toll free: 1-800-222-825
General EPA BX: +91 22 2637 4592 / +91 22 2637 4593
Fax No: +91 22 2634 1274