GENERIC NAME OF THE MEDICINAL PRODUCT:

A. Nifedipine Retard Tablets 10mg
B. Nifedipine Retard Tablets 20mg
C. Nifedipine Retard Tablets 30mg
D. Nifedipine Retard Tablets 40mg
E. Nifedipine Retard Tablets 60mg
F. Nifedipine Retard Tablets 90mg

QUALITATIVE AND QUANTITATIVE COMPOSITION:

A. Nifedipine Retard Tablets 10mg
Each film-coated tablet contains:
Nifedipine USP ………….10mg
Excipients …………………q. s
Color: Sunset yellow FCF

B. Nifedipine Retard Tablets 20mg
Each film-coated tablet contains:
Nifedipine USP …………20mg
Excipients ………………q. s
Color: Ferric oxide red


C. Nifedipine Retard Tablets 30mg
Each film-coated tablet contains:
Nifedipine USP…………….30mg
Excipients ……………………. q. s
Color: Orange G

D. Nifedipine Retard Tablets 40mg
Each film-coated tablet contains:
Nifedipine USP………….40mg
Excipients …………………. q. s
Color: Ponceau 2 R

E. Nifedipine Retard Tablets 60mg
Each film-coated tablet contains:
Nifedipine USP…………….60mg
Excipients……………………q. s
Color: Ponceau 4 R

F. Nifedipine Retard Tablets 90mg
Each film-coated tablet contains:
Nifedipine USP …………….90mg
Excipients……………………q. s
Color: Red oxide of iron

THERAPEUTIC INDICATIONS:

Nifedipine is used to treat high blood pressure and to control angina (chest pain). Nifedipine is in a class of medications called calcium-channel blockers. It lowers blood pressure by relaxing the blood vessels so the heart does not have to pump as hard.

CAUTION & WARNING:

CAUTION: SWALLOW WHOLE DO NOT CHEW OR CRUSH.
Read enclosed leaflet before use.
Dispense in a tight, light-resistant containers as defined in the USP.
WARNING: To be sold by retail on the prescription of a Registered Medical Practitioner only.
KEEP MEDICINE OUT OF REACH OF CHILDREN.

STORAGE & DOSAGE:

Storage: Store at 20°C to 25°C (68° to 77°F); excursions permitted to 15°C to 30°C (59°F to 86°F).
Store in dry place protected from light and moisture.
Dosage: As directed by the Physician.
Attach dispensing label as per end country.

Nifedipine Retard Tablets 20mg Technical Specification:

Product Name:Nifedipine Retard Tablets 20mg
Brand Name:Generic
Strength:10mg, 20mg, 30mg, 40mg, 60mg, 90mg
Dosage Form:Tablets (film-coated)
Route of Administration:Via Oral Route
Packing:10s, 30s, 100s, 500s
Pack Insert/Leaflet:PIL (Patient Information Leaflet), SmPC (Summary Product Characteristics)
Regulatory Documents:COA, MOA, COPP, FSC, Stability Studies, GMP, CTD Dossier
Therapeutic use:Antihypertensive, Antianginal
Indication: Nifedipine is used to treat high blood pressure and to control angina (chest pain). Nifedipine is in a class of medications called calcium-channel blockers. It lowers blood pressure by relaxing the blood vessels so the heart does not have to pump as hard.
Storage:Store at 20°C to 25°C (68° to 77°F); excursions permitted to 15°C to 30°C (59°F to 86°F). Store in dry place protected from light and moisture.

GENERIC NAME OF THE MEDICINAL PRODUCT:

  • Nifedipine Retard Tablets 20mg

QUALITATIVE AND QUANTITATIVE COMPOSITION:

  • Nifedipine Retard Tablets 20mg
    Each film-coated tablet contains:
    Nifedipine USP ………….20mg
    Excipients …………………q. s
    Color: Ferric oxide red

THERAPEUTIC INDICATIONS:

Nifedipine is used to treat high blood pressure and to control angina (chest pain). Nifedipine is in a class of medications called calcium-channel blockers. It lowers blood pressure by relaxing the blood vessels so the heart does not have to pump as hard.

CAUTION & WARNING:

CAUTION: SWALLOW WHOLE DO NOT CHEW OR CRUSH.
Read enclosed leaflet before use.
Dispense in a tight, light-resistant containers as defined in the USP.
Warning: To be sold by retail on the prescription of a Registered Medical Practitioner only.
Keep medicine out of reach of children.

STORAGE & DOSAGE:

Storage: Store at 20°C to 25°C (68° to 77°F); excursions permitted to 15°C to 30°C (59°F to 86°F).
Store in dry place protected from light and moisture.
Dosage: As directed by the Physician.

Why Taj Pharmaceuticals?

Taj Pharmaceuticals presents a compelling choice for healthcare providers and patients seeking Nifedipine Retard Tablets, driven by several pivotal factors. Foremost, Taj Pharmaceuticals has earned a well-deserved reputation for its unwavering commitment to upholding exceptionally high standards of quality in pharmaceutical production. In the realm of pharmaceuticals, particularly with medications like Nifedipine Retard Tablets, where precision and safety are paramount, Taj Pharmaceuticals’ dedication to quality assurance stands as a pillar of confidence for healthcare providers and patients alike. This commitment ensures the medication’s effectiveness and safety, instilling trust in its use. With a wealth of experience in the pharmaceutical industry, Taj Pharmaceuticals has cultivated valuable expertise in the manufacturing and distribution of a diverse array of pharmaceutical products. This extensive experience bolsters the reliability and consistency of their pharmaceutical offerings, establishing them as a trusted and dependable supplier in the field. Taj Pharmaceuticals places a strong emphasis on compliance with stringent regulatory standards and employs rigorous quality control procedures. This unwavering commitment to compliance guarantees that Nifedipine Retard Tablets meet the essential quality and safety requirements mandated by regulatory authorities. Healthcare providers can rest assured that the medication adheres to critical regulations, further enhancing patient safety.

Furthermore, Taj Pharmaceuticals boasts a global presence and a well-established distribution network. This expansive reach ensures that Nifedipine Retard Tablets and other pharmaceutical products are readily available to healthcare providers and patients across various regions. This international accessibility elevates patient care to a global level, ensuring that essential medications are easily obtainable when needed. Taj Pharmaceuticals also dedicates resources to research and development (R&D), recognizing its pivotal role in pharmaceutical advancement. Investment in R&D holds the promise of yielding more effective and advanced formulations of Nifedipine Retard Tablets, potentially enhancing their therapeutic benefits and contributing to improved patient outcomes. Supply reliability is another cornerstone of pharmaceutical provision, and Taj Pharmaceuticals excels in this aspect. A consistent and dependable supply of pharmaceuticals is vital to guarantee that healthcare institutions and patients have uninterrupted access to vital medications.

Consideration of affordability is not overlooked by Taj Pharmaceuticals, as they may offer competitive pricing options for Nifedipine Retard Tablets. This commitment to affordability ensures that the medication remains accessible to healthcare institutions and patients, mitigating financial barriers that could otherwise impede patient care. Lastly, Taj Pharmaceuticals maintains a patient-centric approach, placing a strong emphasis on patient well-being and safety. This alignment perfectly suits the significance of Nifedipine Retard Tablets, which play a pivotal role in managing various cardiovascular conditions. Taj Pharmaceuticals’ dedication to patient safety reinforces the trust placed in their products by healthcare providers and patients alike. In summary, Taj Pharmaceuticals’ steadfast commitment to quality, compliance, research, affordability, and patient support renders them an attractive and reliable choice for healthcare providers seeking a dependable supplier for Nifedipine Retard Tablets and other pharmaceutical needs. Their unwavering focus on patient safety seamlessly aligns with the importance of this medication in managing cardiovascular conditions, ultimately benefiting patient care and outcomes on a global scale.

What is Nifedipine Retard Tablets and its uses:

Nifedipine Retard Tablets are a medication that contains the active ingredient nifedipine, which belongs to a class of drugs known as calcium channel blockers. These tablets are specially formulated to release the medication slowly over time, providing extended therapeutic effects. Here are its primary uses:

  • Hypertension (High Blood Pressure): Nifedipine Retard Tablets are commonly prescribed to manage high blood pressure (hypertension). They work by relaxing the blood vessels, reducing the resistance in the arteries, and thereby lowering blood pressure. The extended-release formulation allows for once-daily dosing, which can improve patient adherence to treatment.
  • Angina Pectoris: Nifedipine Retard Tablets are also used to treat angina pectoris, a condition characterized by chest pain or discomfort due to reduced blood flow to the heart muscle. By dilating the coronary arteries and improving blood supply to the heart, nifedipine helps relieve angina symptoms and reduce the frequency and severity of angina attacks.
  • Raynaud’s Phenomenon: Nifedipine may be prescribed to individuals with Raynaud’s phenomenon, a condition in which certain areas of the body (usually fingers and toes) experience extreme cold-induced vasospasms, leading to numbness, tingling, and color changes. The medication’s vasodilatory effects can help alleviate these symptoms.
  • Preterm Labor: In some cases, healthcare providers may use nifedipine (not necessarily the extended-release formulation) as a tocolytic agent to delay preterm labor and postpone premature birth. It helps relax the uterine muscles, temporarily halting contractions.

It’s important to note that Nifedipine Retard Tablets should only be used under the supervision and prescription of a healthcare provider. The dosage and duration of treatment will be determined based on the specific medical condition, patient response, and individual factors. Self-medication and abrupt discontinuation of this medication can lead to adverse effects and should be avoided. Always follow the guidance of a healthcare professional when using Nifedipine Retard Tablets.

How does Nifedipine Retard Tablets work?

Nifedipine Retard Tablets work by blocking the influx of calcium ions into smooth muscle cells in the walls of blood vessels and the heart. This mechanism of action allows the medication to achieve several therapeutic effects, primarily in the treatment of hypertension (high blood pressure) and angina pectoris (chest pain). Here’s how Nifedipine Retard Tablets work:

  • Vasodilation: Nifedipine, the active ingredient in these tablets, is a calcium channel blocker. It specifically blocks L-type calcium channels in smooth muscle cells lining blood vessels. By inhibiting these calcium channels, nifedipine prevents the influx of calcium ions into the smooth muscle cells. As a result, the smooth muscle relaxes and does not contract as forcefully. This relaxation leads to the dilation (widening) of arteries and arterioles throughout the body, reducing peripheral vascular resistance. With decreased resistance, the blood vessels widen, allowing blood to flow more easily. This vasodilation lowers blood pressure, making Nifedipine Retard Tablets effective in managing hypertension.
  • Decreased Cardiac Workload: Nifedipine’s vasodilatory effect also extends to the coronary arteries that supply the heart muscle. By dilating these arteries, the medication increases blood flow to the heart, improving oxygen delivery to cardiac cells. This reduced cardiac workload is particularly beneficial for individuals with angina pectoris. It helps alleviate chest pain by ensuring that the heart muscle receives an adequate oxygen supply, reducing the frequency and severity of angina attacks.
  • Reduced Myocardial Oxygen Demand: Nifedipine can lower the heart’s oxygen demand by reducing the afterload (the resistance the heart has to overcome to pump blood) and the preload (the amount of blood returning to the heart). As a result, the heart requires less oxygen to function, which can be advantageous for individuals with angina and certain heart conditions.
  • Vasodilation in Raynaud’s Phenomenon: In Raynaud’s phenomenon, Nifedipine’s vasodilatory properties are used to relax the small blood vessels in the fingers and toes. This helps counteract vasospasms, improving blood flow and reducing symptoms like numbness and color changes.
  • Tocolytic Action: In cases of preterm labor, Nifedipine may be used as a tocolytic agent. It relaxes the uterine muscles, delaying contractions and temporarily preventing premature labor.

Benefits of Nifedipine Retard Tablets:

  • Blood Pressure Control: Nifedipine Retard Tablets are effective in lowering high blood pressure (hypertension) by relaxing blood vessel walls, reducing resistance, and allowing for better blood flow. This helps decrease the workload on the heart and can prevent complications associated with high blood pressure, such as heart attacks, strokes, and kidney problems.
  • Angina Relief: These tablets provide relief from angina pectoris, a condition characterized by chest pain or discomfort due to reduced blood flow to the heart muscle. By dilating coronary arteries and improving blood supply to the heart, Nifedipine Retard Tablets alleviate angina symptoms, making physical activity more tolerable for individuals with this condition.
  • Raynaud’s Phenomenon Management: Nifedipine can help manage Raynaud’s phenomenon, a condition causing cold-induced vasospasms in extremities like fingers and toes. The medication’s vasodilatory effects relax blood vessels, reducing vasospasms, and improving blood flow, which can relieve symptoms such as numbness and color changes.
  • Tocolytic Action: In cases of preterm labor, Nifedipine may be used as a tocolytic agent to delay contractions temporarily. This can help prolong pregnancy and improve neonatal outcomes.

Side Effects of Nifedipine Retard Tablets:

  • Hypotension: Nifedipine can cause low blood pressure (hypotension), leading to symptoms like dizziness, lightheadedness, and fainting. It’s important to rise slowly from sitting or lying positions to minimize this risk.
  • Peripheral Edema: Swelling of the ankles and feet (peripheral edema) is a common side effect of Nifedipine. It occurs due to the medication’s vasodilatory effects, which can lead to fluid accumulation in the extremities.
  • Headache: Some individuals may experience headaches as a side effect of Nifedipine.
  • Flushing: Flushing or a sensation of warmth in the face and neck is another possible side effect.
  • Gastrointestinal Symptoms: Nifedipine can occasionally cause gastrointestinal symptoms such as nausea, abdominal discomfort, and constipation.
  • Reflex Tachycardia: In response to the vasodilatory effects of Nifedipine, the body may sometimes increase heart rate (reflex tachycardia) to maintain blood pressure. This can be a temporary side effect.
  • Gingival Hyperplasia: Rarely, long-term use of Nifedipine may lead to gum overgrowth (gingival hyperplasia). Good oral hygiene practices are recommended to reduce this risk.
  • Rare and Severe Side Effects: While uncommon, Nifedipine can have more serious side effects, including an irregular heartbeat, worsening chest pain, and allergic reactions. If any unusual or severe symptoms occur, medical attention should be sought immediately.

It’s crucial to take Nifedipine Retard Tablets as prescribed by a healthcare provider and to report any side effects promptly. Adjustments to the medication regimen or alternative treatments may be considered to manage side effects while maintaining therapeutic benefits.

Frequently Asked Questions About Nifedipine Retard Tablets:

Certainly, here are some frequently asked questions (FAQs) about Nifedipine Retard Tablets:

  1. What are Nifedipine Retard Tablets used for?

Nifedipine Retard Tablets are primarily used to treat high blood pressure (hypertension) and angina pectoris (chest pain or discomfort). They are also used to manage conditions like Raynaud’s phenomenon and, in some cases, to delay preterm labor.

  1. How do Nifedipine Retard Tablets work?

Nifedipine Retard Tablets belong to a class of medications called calcium channel blockers. They work by blocking calcium channels in smooth muscle cells lining blood vessels and the heart. This leads to relaxation of blood vessels, reduced vascular resistance, improved blood flow, and decreased cardiac workload, which ultimately lowers blood pressure and relieves angina.

  1. Are Nifedipine Retard Tablets the same as regular Nifedipine tablets?

Nifedipine Retard Tablets are a specially formulated extendedrelease version of Nifedipine. The key difference is in the release rate of the medication. While regular Nifedipine tablets provide a rapid release of the drug, Nifedipine Retard Tablets release the medication slowly over time, allowing for oncedaily dosing in many cases.

  1. How should I take Nifedipine Retard Tablets?

Follow your healthcare provider’s instructions carefully. Nifedipine Retard Tablets are typically taken orally with or without food. It’s essential to take them at the same time each day and not to crush or chew the tablets. Swallow them whole.

  1. Can Nifedipine Retard Tablets cause low blood pressure?

Yes, Nifedipine Retard Tablets can cause low blood pressure (hypotension) as a side effect. It’s important to rise slowly from sitting or lying positions to minimize the risk of dizziness or fainting.

  1. What are the potential side effects of Nifedipine Retard Tablets?

Common side effects may include peripheral edema (swelling of the ankles and feet), headache, flushing, gastrointestinal symptoms, and reflex tachycardia (increased heart rate). Serious side effects are rare but may include irregular heartbeat, worsening chest pain, and allergic reactions.

  1. Can I stop taking Nifedipine Retard Tablets abruptly?

No, it’s generally not advisable to stop taking Nifedipine Retard Tablets abruptly without consulting your healthcare provider. Abrupt discontinuation can lead to a rebound increase in blood pressure or worsening of angina symptoms. Any changes to your medication regimen should be discussed with your healthcare provider.

  1. Can I drink alcohol while taking Nifedipine Retard Tablets?

It’s generally best to limit alcohol consumption while taking Nifedipine Retard Tablets, as alcohol can potentiate the medication’s blood pressurelowering effects and increase the risk of side effects.

  1. Are there any drug interactions with Nifedipine Retard Tablets?

Nifedipine may interact with certain medications, including other blood pressurelowering drugs, grapefruit juice, and some antibiotics. Inform your healthcare provider about all medications and supplements you are taking to avoid potential interactions.

  1. Can Nifedipine Retard Tablets be used during pregnancy and breastfeeding?

The use of Nifedipine during pregnancy and breastfeeding should be carefully considered and supervised by a healthcare provider. It may be used if the potential benefits outweigh the risks, but close monitoring is essential.

These FAQs provide valuable information about Nifedipine Retard Tablets, their uses, potential side effects, and considerations for their safe and effective use. Always consult with your healthcare provider for personalized guidance regarding this medication.

As Nifedipine Retard Tablets Exporters; We can cater to export business queries from the following geographies. We are exporting our Nifedipine Retard Tablets product in the Following Countries-

Russia and CIS Countries: Azerbaijan, Armenia, Belarus, Georgia, Kazakhstan, Kyrgyzstan, Moldova, Russia, Tajikistan, Turkmenistan, Uzbekistan and Ukraine

GCC/ Middle East Countries: Saudi Arabia, Yemen, Oman, Bahrain, UAE, Lebanon, Jordan, and Iraq.

African Countries: Nigeria, Tanzania, Sudan, Zambia, Benin, Angola, Liberia

Southeast Asia: Cambodia, Indonesia, Laos, Malaysia, Myanmar, Philippines, Singapore, Thailand, Vietnam, Brunei Darussalam

Other Asian Countries: Nepal, Myanmar, Malaysia, Cambodia, Bhutan, Sri Lanka, Mauritius

Nifedipine Retard Tablets Regulatory Documents:

  • Certificate of Analysis (COA)
  • Method of Analysis (MOA)
  • Stability Data (Accelerated stability / Long-term stability / Zone 4b)
  • CTD Dossier / ACTD Dossiers / eCTD Dossiers
  • Certificate of Pharmaceuticals Product (COPP)
  • Free Sale Certificate (FSC)
Contact the most reliable manufacturer of Nifedipine Retard Tablets, Taj Pharmaceuticals Limited to get bulk quantities at a reasonable price.

To Place Orders:

Direct line: +91 8448 444 095 / WhatsApp +91 74 0000 9975 / 74 0000 9976
E-Mail: info@tajpharma.com 
Toll free: 1-800-222-434 / Toll free: 1-800-222-825
General EPA BX: +91 22 2637 4592 / +91 22 2637 4593
Fax No: +91 22 2634 1274