GENERIC NAME OF THE MEDICINAL PRODUCT:

A) Metoprolol Succinate Extended-Release Tablet USP 25mg
B) Metoprolol Succinate Extended-Release Tablet USP 50mg
C) Metoprolol Succinate Extended-Release Tablet USP 1000mg
D) Metoprolol Succinate Extended-Release Tablet USP 200mg

QUALITATIVE AND QUANTITATIVE COMPOSITION:

A) Metoprolol Succinate Extended-Release Tablet USP 25mg
Each film -coated Extended-Release tablet contain:
Metoprolol Succinate
Eq. to Metoprolol Tartrate USP……...............25mg
Excipients………………………………………….…………. q.s.
Colour: Sunset yellow FCF


B) Metoprolol Succinate Extended-Release Tablet USP 50mg
Each film-coated Extended-Release tablet contain:
Metoprolol Succinate
Eq. to Metoprolol Tartrate USP.……..............50mg
Excipients………………………………………….…………. q.s.
Colour: Titanium Dioxide USP

C) Metoprolol Succinate Extended-Release Tablet USP 100mg
Each film-coated Extended-Release tablet contain:
Metoprolol Succinate
Eq. to Metoprolol Tartrate USP …..............100mg
Excipients………………………………….…………. q.s.
Colour: Iron oxide Red

D) Metoprolol Succinate Extended-Release Tablet USP 200mg
Each film-coated Extended-Release tablet contain:
Metoprolol Succinate
Eq. to Metoprolol Tartrate USP …...........200mg
Excipients………………………………….…………. q.s.
Colour: Iron oxide Black

THERAPEUTIC INDICATIONS:

Metoprolol Succinate ER is a beta-blocker that affects the heart and circulation (blood flow through arteries and veins). Metoprolol Succinate ER is used to treat angina (chest pain) and hypertension (high blood pressure). It is also used to lower your risk of death or needing to be hospitalized for heart failure.

CAUTION & WARNING:

CAUTION: SWALLOW WHOLE DO NOT CHEW OR CRUSH.
Take whole tablet with water.
Read enclosed leaflet before use.
WARNING: To be sold by retail on the prescription of a Registered Medical Practitioner only.
KEEP MEDICINE OUT OF REACH OF CHILDREN.

STORAGE & DOSAGE:

Storage: Store at 20° to 25°C (68° to 77°F).
Protect from light & moisture.
Keep in a cool & dry place.
Dosage: As directed by the Physician
Attach dispensing label here.

Metoprolol Succinate Extended-Release Tablet USP 25mg Technical Specification:

Product Name:Metoprolol Succinate Extended-Release Tablet USP 25mg
Brand Name:Metorol XL
Strength:25mg, 50mg, 100mg, 200mg
Dosage Form:Extended-Release Tablets (film-coated)
Route of Administration:Via Oral Route
Packing:10s, 20s, 30s, 50s, 150s
Pack Insert/Leaflet:PIL (Patient Information Leaflet), SmPC (Summary Product Characteristics)
Regulatory Documents:COA, MOA, COPP, FSC, Stability Studies, GMP, CTD Dossier
Therapeutic use:Anti-anginal
Indication: Metoprolol Succinate ER is a beta-blocker that affects the heart and circulation (blood flow through arteries and veins). Metoprolol Succinate ER is used to treat angina (chest pain) and hypertension (high blood pressure). It is also used to lower your risk of death or needing to be hospitalized for heart failure.
Storage:Store at 20° to 25°C (68° to 77°F). Protect from light & moisture. Keep in a cool & dry place.

GENERIC NAME OF THE MEDICINAL PRODUCT:

  • Metoprolol Succinate Extended-Release Tablet USP 25mg

QUALITATIVE AND QUANTITATIVE COMPOSITION:

  • Metoprolol Succinate Extended-Release Tablet USP 25mg
    Each film -coated Extended-Release tablet contain:
    Metoprolol Succinate
    Eq. to Metoprolol Tartrate USP…………………25mg
    Excipients………………………………………….…………. q.s.
    Colour: Sunset yellow FCF

THERAPEUTIC INDICATIONS:

Metoprolol Succinate ER is a beta-blocker that affects the heart and circulation (blood flow through arteries and veins). Metoprolol Succinate ER is used to treat angina (chest pain) and hypertension (high blood pressure). It is also used to lower your risk of death or needing to be hospitalized for heart failure.

CAUTION & WARNING:

CAUTION: SWALLOW WHOLE DO NOT CHEW OR CRUSH.

Take whole tablet with water.

Read enclosed leaflet before use.

Warning:  To be sold by retail on the prescription of a Registered Medical Practitioner only.

Keep medicine out of reach of children.

STORAGE & DOSAGE:

Storage: Store at 20° to 25°C (68° to 77°F). Protect from light & moisture. Keep in a cool & dry place.

Dosage:  As directed by the Physician

Attach dispensing label here.

Why Taj Pharmaceuticals?

  • Pharmaceutical Excellence: Taj Pharmaceuticals boasts a long-standing reputation for pharmaceutical excellence. With a focus on producing high-quality medications, they have earned the trust of healthcare professionals and patients worldwide. Their dedication to delivering effective and safe pharmaceuticals makes them a reliable choice for cardiovascular health.
  • Expertise in Cardiovascular Health: Taj Pharmaceuticals specializes in cardiovascular medications, including Metoprolol Succinate ER Tablets. Their in-depth knowledge of heart-related conditions ensures that individuals receive tailored solutions for managing hypertension, angina, and other cardiovascular issues.
  • Global Accessibility: Taj Pharmaceuticals’ extensive distribution network ensures that Metoprolol Succinate ER Tablets are readily available to individuals and healthcare systems across the globe. This global accessibility is crucial for addressing the widespread prevalence of cardiovascular conditions.
  • Patient-Centric Approach: Taj Pharmaceuticals prioritizes patient well-being and strives to improve the quality of life for those dealing with heart-related conditions. Their medications are designed to provide effective symptom relief while minimizing side effects, enhancing overall cardiovascular comfort.
  • Comprehensive Cardiovascular Portfolio: Taj Pharmaceuticals offers a wide range of cardiovascular medications, allowing healthcare providers to select the most suitable treatment options for their patients. This comprehensive approach ensures personalized care for individuals with varying cardiovascular needs.
  • Quality Assurance: Taj Pharmaceuticals adheres to stringent quality control measures to ensure that Metoprolol Succinate ER Tablets meet the highest pharmaceutical standards. Quality and safety are paramount in their production processes.
  • Affordability: Taj Pharmaceuticals is committed to providing cost-effective solutions for managing cardiovascular health. Their medications are designed to be accessible without compromising quality, making them an excellent choice for individuals seeking budget-friendly options.

In summary, Taj Pharmaceuticals is your dependable source for Metoprolol Succinate ER Tablets, offering pharmaceutical excellence, cardiovascular expertise, global accessibility, patient-centric care, a comprehensive portfolio, quality assurance, and affordability. When it comes to managing heart-related conditions, trust Taj Pharmaceuticals for personalized, effective, and safe solutions that prioritize your cardiovascular well-being.

What is Metoprolol Succinate ER Tablets and its uses:

Metoprolol Succinate ER Tablets are a medication that contains the active ingredient metoprolol succinate in an extended release (ER) form. Metoprolol is a betablocker, and the “ER” designation indicates that it provides a sustained release of the medication over an extended period. Here are its primary uses:

  1. Hypertension (High Blood Pressure): Metoprolol Succinate ER Tablets are commonly prescribed to lower high blood pressure. By blocking the effects of adrenaline on the heart and blood vessels, metoprolol reduces the heart rate and dilates blood vessels, which results in decreased blood pressure.
  1. Angina Pectoris (Chest Pain): Individuals with angina pectoris, a condition characterized by chest pain or discomfort due to reduced blood flow to the heart muscle, may benefit from these tablets. Metoprolol helps reduce the workload on the heart, making it easier for the heart to pump blood and oxygen to the heart muscle.
  1. Heart Failure: In some cases of heart failure, metoprolol succinate in its extended release form can be used. It helps improve the heart’s efficiency and reduce the symptoms of heart failure, such as shortness of breath and fatigue.
  1. Prevention of Migraine Headaches: Metoprolol is sometimes prescribed to prevent migraine headaches. It is believed to work by relaxing blood vessels and reducing the frequency and severity of migraine attacks.
  1. Atrial Fibrillation and Supraventricular Tachycardia: Metoprolol may be used to control rapid or irregular heart rhythms, such as atrial fibrillation or supraventricular tachycardia, by slowing down the heart rate.
  1. Post Myocardial Infarction (Heart Attack) Management: After a heart attack, metoprolol succinate ER tablets can help improve the heart’s pumping ability, reduce the risk of future heart related events, and enhance overall cardiovascular function.

It’s essential to use Metoprolol Succinate ER Tablets as prescribed by a healthcare provider, as the dosage and duration of treatment will depend on the specific medical condition and individual patient needs. This medication should not be discontinued abruptly without medical supervision, as it can lead to a rebound increase in blood pressure or other heart related issues. Always follow your healthcare provider’s guidance and recommendations regarding its use.

How do Metoprolol Succinate ER Tablets work?

Metoprolol Succinate ER Tablets work primarily through the action of their active ingredient, metoprolol succinate, which belongs to a class of medications known as beta-blockers. Here’s how they work:

  • Beta-Adrenergic Receptor Blockade: Metoprolol is a selective beta-1 adrenergic receptor blocker. It competes with the neurotransmitter adrenaline (epinephrine) for binding to beta-1 receptors in the heart and other tissues.
  • Reducing Heart Rate: When adrenaline binds to beta-1 receptors, it increases the heart rate and the force of heart contractions. Metoprolol blocks these receptors, preventing adrenaline from exerting its stimulatory effects. As a result, the heart rate decreases, and the heart beats more efficiently.
  • Lowering Blood Pressure: By reducing the heart rate and the force of heart contractions, metoprolol decreases the overall workload on the heart. This leads to a reduction in cardiac output, which, in turn, lowers blood pressure. Additionally, metoprolol may also decrease the release of renin, an enzyme involved in blood pressure regulation.
  • Dilation of Blood Vessels: Metoprolol may cause some vasodilation, which means it relaxes and widens blood vessels. This dilation helps to reduce peripheral resistance in the blood vessels, making it easier for the heart to pump blood and lowering blood pressure.
  • Antiarrhythmic Effects: Metoprolol can stabilize heart rhythms. It is often used to control rapid or irregular heart rhythms, such as atrial fibrillation, by slowing down the heart rate and preventing the transmission of abnormal electrical impulses.
  • Improving Myocardial Oxygen Supply: By reducing the workload and oxygen demand of the heart, metoprolol can enhance oxygen supply to the myocardium (the heart’s muscle tissue). This is particularly beneficial in cases of angina pectoris, where reduced oxygen supply to the heart muscle can lead to chest pain.
  • Management of Heart Failure: In heart failure, metoprolol succinate ER tablets can help improve the heart’s pumping ability and reduce symptoms by blocking the effects of excessive sympathetic nervous system stimulation, which is common in heart failure.

It’s important to note that the extended-release (ER) formulation of metoprolol succinate allows for a gradual and sustained release of the medication over time. This means that the therapeutic effects are prolonged, and fewer daily doses are required compared to immediate-release forms. The overall goal of Metoprolol Succinate ER Tablets is to improve cardiovascular function, reduce symptoms, and manage conditions such as high blood pressure, angina, arrhythmias, and heart failure. The specific use and dosage of this medication should be determined by a healthcare provider based on the individual’s medical condition and response to treatment.

Benefits of Metoprolol Succinate ER Tablets:

  • Hypertension Management: Metoprolol Succinate ER Tablets are highly effective in lowering high blood pressure, reducing the risk of cardiovascular events, and promoting overall cardiovascular health.
  • Angina Relief: Individuals with angina pectoris benefit from reduced chest pain and discomfort as Metoprolol helps the heart work more efficiently and reduces the heart’s oxygen demand.
  • Heart Rhythm Control: Metoprolol is effective in controlling rapid or irregular heart rhythms, such as atrial fibrillation or supraventricular tachycardia, by slowing down the heart rate and stabilizing heart rhythms.
  • Heart Failure Management: These tablets can improve the heart’s pumping ability and reduce symptoms in individuals with heart failure, leading to enhanced quality of life and increased exercise tolerance.
  • Migraine Prevention: Metoprolol may reduce the frequency and severity of migraine headaches, providing relief for individuals prone to migraines.

Side Effects of Metoprolol Succinate ER Tablets:

  • Bradycardia (Slow Heart Rate): Metoprolol can lower the heart rate, and in some cases, it may lead to bradycardia, characterized by an excessively slow heart rate. This effect is usually dose-dependent and may require a dose adjustment.
  • Hypotension (Low Blood Pressure): While lowering high blood pressure is a therapeutic benefit, excessive lowering of blood pressure can result in hypotension, leading to dizziness or fainting.
  • Fatigue and Weakness: Some individuals may experience fatigue, weakness, or a lack of energy as a side effect of metoprolol. These symptoms are generally mild and improve with time.
  • Cold Extremities: Metoprolol may cause cold hands and feet, which can be uncomfortable for some individuals.
  • Gastrointestinal Issues: Gastrointestinal side effects like nausea, vomiting, and diarrhea can occur but are relatively uncommon.
  • Insomnia or Sleep Disturbances: A small percentage of individuals may experience sleep disturbances, such as insomnia, while taking metoprolol.
  • Bronchospasm (in Asthma Patients): Metoprolol should be used with caution in individuals with asthma or chronic obstructive pulmonary disease (COPD), as it may exacerbate bronchospasm.
  • Mental Health Effects: In rare cases, metoprolol may contribute to mood changes, including depression or vivid dreams.
  • Masking of Hypoglycemia: Metoprolol can mask some of the symptoms of low blood sugar in individuals with diabetes, making it important for those with diabetes to monitor their blood sugar levels closely.
  • Allergic Reactions (Rare): In very rare cases, metoprolol may trigger allergic reactions, such as skin rash, itching, or swelling.

It’s crucial to take Metoprolol Succinate ER Tablets as prescribed by a healthcare provider and to report any severe or persistent side effects promptly. Dosage adjustments or alternative treatments may be considered if side effects are troublesome. Overall, the benefits of metoprolol in managing cardiovascular conditions often outweigh the potential side effects, especially when used under medical supervision.

Frequently Asked Questions About Metoprolol Succinate ER Tablets:

Certainly, here are some frequently asked questions (FAQs) about Metoprolol Succinate ER Tablets:

  1. What are Metoprolol Succinate ER Tablets, and what is their primary purpose?

Metoprolol Succinate ER Tablets are a medication containing the active ingredient metoprolol, a betablocker. They are primarily used to treat conditions like high blood pressure, angina (chest pain), heart rhythm disorders, and heart failure.

  1. How do Metoprolol Succinate ER Tablets differ from regular metoprolol tablets?

The “ER” in Metoprolol Succinate ER stands for “extended release.” These tablets are formulated to release the medication gradually over an extended period, allowing for once daily dosing, while regular metoprolol tablets are immediate release and often require multiple doses throughout the day.

  1. Can I stop taking Metoprolol Succinate ER Tablets suddenly?

No, it’s essential not to discontinue this medication abruptly without consulting your healthcare provider. Suddenly stopping metoprolol can lead to rebound high blood pressure, worsened angina symptoms, or other heart related issues. Your healthcare provider will guide you on how to taper the medication if necessary.

  1. Can Metoprolol Succinate ER Tablets be taken with or without food?

These tablets can generally be taken with or without food. However, it’s a good idea to take them the same way each day to maintain consistent blood levels.

  1. Are there any potential interactions with other medications or supplements?

Metoprolol can interact with various medications and supplements. Inform your healthcare provider about all the medications, supplements, and herbal products you are taking to avoid potential interactions.

  1. Can Metoprolol Succinate ER Tablets be used during pregnancy or breastfeeding?

Pregnant or breastfeeding individuals should consult their healthcare provider before using this medication. The decision to use Metoprolol during pregnancy or breastfeeding should be made based on individual circumstances and the potential risks and benefits.

  1. What should I do if I miss a dose of Metoprolol Succinate ER Tablets?

If you miss a dose, take it as soon as you remember. However, if it’s close to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double up on doses to make up for a missed one.

  1. What are the potential side effects of Metoprolol Succinate ER Tablets?

Common side effects may include fatigue, dizziness, slow heart rate, cold extremities, and gastrointestinal issues. Serious side effects are rare but can include allergic reactions, worsening heart failure, or changes in blood sugar levels.

  1. Is it safe to consume alcohol while taking Metoprolol Succinate ER Tablets?

Alcohol consumption should be moderated while taking metoprolol, as it can enhance the medication’s side effects, such as dizziness or light-headedness.

  1. How long does it take for Metoprolol Succinate ER Tablets to start working?

The onset of action may vary, but some individuals experience a reduction in blood pressure and symptom relief within hours to a few days of starting the medication. However, full therapeutic effects may take several weeks.

These FAQs provide general information about Metoprolol Succinate ER Tablets, but individual recommendations and usage may vary. Always consult with a healthcare provider for personalized advice and guidance on the use of this medication, including potential benefits and risks.

As Metoprolol Succinate ER Tablets Exporters; We can cater to export business queries from the following geographies. We are exporting our Metoprolol Succinate ER Tablets product in the Following Countries-

Russia and CIS Countries: Azerbaijan, Armenia, Belarus, Georgia, Kazakhstan, Kyrgyzstan, Moldova, Russia, Tajikistan, Turkmenistan, Uzbekistan and Ukraine

GCC/ Middle East Countries: Saudi Arabia, Yemen, Oman, Bahrain, UAE, Lebanon, Jordan, and Iraq.

African Countries: Nigeria, Tanzania, Sudan, Zambia, Benin, Angola, Liberia

Southeast Asia: Cambodia, Indonesia, Laos, Malaysia, Myanmar, Philippines, Singapore, Thailand, Vietnam, Brunei Darussalam

Other Asian Countries: Nepal, Myanmar, Malaysia, Cambodia, Bhutan, Sri Lanka, Mauritius

Metoprolol Succinate ER Tablets Regulatory Documents:

  • Certificate of Analysis (COA)
  • Method of Analysis (MOA)
  • Stability Data (Accelerated stability / Long-term stability / Zone 4b)
  • CTD Dossier / ACTD Dossiers / eCTD Dossiers
  • Certificate of Pharmaceuticals Product (COPP)
  • Free Sale Certificate (FSC)
Contact the most reliable manufacturer of Metoprolol Succinate ER Tablets, Taj Pharmaceuticals Limited, to get bulk quantities at a reasonable price.

To Place Orders:

Direct line: +91 8448 444 095 / WhatsApp +91 74 0000 9975 / 74 0000 9976
E-Mail: info@tajpharma.com 
Toll free: 1-800-222-434 / Toll free: 1-800-222-825
General EPA BX: +91 22 2637 4592 / +91 22 2637 4593
Fax No: +91 22 2634 1274