GENERIC NAME OF THE MEDICINAL PRODUCT:

A. Mesalazine Pellets 0.5g
B. Mesalazine Pellets 1g
C. Mesalazine Pellets 2g

QUALITATIVE AND QUANTITATIVE COMPOSITION:

A. Mesalazine Pellets 0.5g
Each sachet contains:
Mesalazine IP …………… 0.5g
(As pellets)
Excipients……………………………. q.s


B. Mesalazine Pellets 1g
Each sachet contains:
Mesalazine IP …………… 1g
(As pellets)
Excipients……………………………. q.s

C. Mesalazine Pellets 2g Each sachet contains:
Mesalazine IP …………… 2g
(As pellets)
Excipients……………………………. q.s

THERAPEUTIC INDICATIONS:

Mesalazine is indicated for the induction of remission in patients with active or mild to moderate acute exacerbations of ulcerative colitis and for the maintenance of remission of ulcerative colitis.

CAUTION & SCHEDULE:

CAUTION: Oral for inflammatory bowel diseases.
Read enclosed leaflet before use.
SCHEDULE: SCHEDULE H Drug- Warning: To be sold by retail on the prescription of a Registered Medical Practitioner only.
KEEP MEDICINE OUT OF REACH OF CHILDREN.

STORAGE & DOSAGE:

Storage: Store in a cool & dry place.
Protect from light & moisture.
Preserve in a tight container.
Dosage: As directed by physician.

Mesalazine Pellets 0.5g Technical Specification:

Product Name:                                     Mesalazine Pellets 0.5g
Brand Name:Meslataj
Strength:0.5g, 1g, 2g
Dosage Form:Sachet
Route of Administration:Via oral Route
Packing:30 sachet, 120 sachet
Pack Insert/Leaflet:PIL (Patient Information Leaflet)
Regulatory Documents:COA, MOA, Stability Studies, GMP
Therapeutic use:Anti-inflammatory
Indication: Mesalazine is indicated for the induction of remission in patients with active or mild to moderate acute exacerbations of ulcerative colitis and for the maintenance of remission of ulcerative colitis.
Storage:Store in a cool & dry place. Protect from light & moisture. Preserve in a tight container.

GENERIC NAME OF THE MEDICINAL PRODUCT:

  • Mesalazine Pellets 0.5g

QUALITATIVE AND QUANTITATIVE COMPOSITION:

  • Mesalazine Pellets 0.5g
    Each sachet contains:
    Mesalazine IP …………… 0.5g
    (As pellets)
    Excipients……………………………. q.s

THERAPEUTIC INDICATIONS:

Mesalazine is indicated for the induction of remission in patients with active or mild to moderate acute exacerbations of ulcerative colitis and for the maintenance of remission of ulcerative colitis.

CAUTION & schedule:

CAUTION:  Oral for inflammatory bowel diseases.

Read enclosed leaflet before use.

schedule: schedule H Drug- Warning: To be sold by retail on the prescription of a Registered Medical Practitioner only.

Keep medicine out of reach of children.

STORAGE & DOSAGE:

Storage:  Store in a cool & dry place. Protect from light & moisture. Preserve in a tight container.

Dosage:  As directed by physician.

Why Taj Pharmaceuticals?

Taj Pharma is your trusted choice for Mesalazine Pellets. Our commitment to quality, affordability, and innovation makes us the preferred pharmaceutical partner for Mesalazine formulations. At Taj Pharma, we stand at the forefront of Mesalazine Pellets production, offering a reliable and cost-effective solution for gastrointestinal disorders. With a proven track record of excellence, our commitment to quality assurance, affordability, and continuous innovation sets us apart as the preferred pharmaceutical partner for Mesalazine formulations.

Choose Taj Pharma for:

  • Quality Assurance: We adhere to stringent quality standards to ensure that our Mesalazine Pellets meet the highest quality benchmarks, ensuring efficacy and safety for patients.
  • Affordability: We believe that healthcare should be accessible to all. Our competitive pricing for Mesalazine Pellets makes treatment more affordable for patients, without compromising on quality.
  • Innovation: Taj Pharma is dedicated to innovation in pharmaceuticals. Our state-of-the-art research and development facilities continuously strive to improve Mesalazine formulations, enhancing their effectiveness and patient compliance.
  • Global Reach: With a global presence, Taj Pharma ensures that Mesalazine Pellets are available to patients and healthcare providers worldwide, making treatment accessible to those in need.

What is Mesalazine Pellets and its use?

Mesalazine pellets are a pharmaceutical formulation of the medication mesalazine (also known as mesalamine) that is used to treat various inflammatory bowel diseases (IBD), particularly ulcerative colitis and Crohn’s disease. These pellets contain mesalazine as the active ingredient and are designed to release the medication gradually in the digestive tract, ensuring targeted and sustained therapeutic effects. Here’s a brief overview of mesalazine pellets and their use:

  • Active Ingredient: Mesalazine is an anti-inflammatory drug that works locally in the digestive tract. It helps reduce inflammation and symptoms associated with inflammatory bowel diseases.
  • Formulation: Mesalazine pellets are small, bead-like particles that contain the active ingredient. These pellets are typically enclosed in a capsule or tablet, allowing for controlled release of mesalazine throughout the gastrointestinal tract.
  • Targeted Treatment: The controlled release of mesalazine from the pellets allows for targeted treatment of inflamed areas in the colon and rectum, which are commonly affected by ulcerative colitis. It can also be used in Crohn’s disease to treat inflammation in various parts of the digestive tract.
  • Ulcerative Colitis: Mesalazine is often used as a first-line treatment for mild to moderate cases of ulcerative colitis, helping reduce symptoms like diarrhea, abdominal pain, and rectal bleeding.
  • Crohn’s Disease: In Crohn’s disease, mesalazine may be used in certain situations to manage inflammation and symptoms, although it is typically more effective in ulcerative colitis.
  • Maintenance Therapy: In addition to treating active disease flare-ups, mesalazine pellets are commonly used as maintenance therapy to help prevent relapses and maintain remission in patients with ulcerative colitis.
  • Minimizing Systemic Side Effects: One advantage of mesalazine pellets is that they work primarily within the digestive tract, minimizing systemic side effects often associated with other anti-inflammatory medications.
  • Dosage: The dosage and regimen of mesalazine pellets vary depending on the specific condition being treated and the severity of the disease. Dosage instructions should be followed as prescribed by a healthcare provider.

How does Mesalazine Pellets work?

Mesalazine pellets work by delivering the active ingredient, mesalazine (also known as mesalazine), to the gastrointestinal tract, where they exert their anti-inflammatory effects. The mechanism of action of mesalazine is not entirely understood, but it is believed to involve several processes within the digestive tract. Here’s how mesalazine pellets work:

  • Anti-Inflammatory Effects: Mesalazine is an anti-inflammatory drug. It is thought to reduce inflammation by inhibiting the production of inflammatory chemicals, such as prostaglandins and leukotrienes, and by modulating the immune response in the gut. In inflammatory bowel diseases (IBD) like ulcerative colitis and Crohn’s disease, the immune system mistakenly attacks the lining of the digestive tract, leading to inflammation. Mesalazine helps to dampen this immune response and reduce inflammation.
  • Local Action: Mesalazine pellets are designed to release the medication gradually and locally within the gastrointestinal tract. This controlled release allows for the drug to act directly on the inflamed areas of the colon and rectum in the case of ulcerative colitis, or on various segments of the digestive tract in the case of Crohn’s disease.
  • Topical Treatment: Mesalazine’s primary benefit is its topical treatment of the inflamed areas, meaning it works directly on the surface of the intestinal lining without being significantly absorbed into the bloodstream. This localized action helps to minimize systemic side effects that are often associated with other systemic anti-inflammatory medications.
  • Prevention of Relapse: In addition to its anti-inflammatory properties, mesalazine is often used as maintenance therapy. It helps to prevent relapses and maintain remission in patients with IBD. By providing ongoing anti-inflammatory activity in the gut, mesalazine reduces the likelihood of disease flare-ups.
  • Stool and Urine Acidic pH: Mesalazine’s effectiveness is influenced by the pH (acidity) of the stool and urine. It is believed that mesalazine is most effective when the pH in the gut is acidic. Therefore, the drug’s action can be influenced by factors that affect the pH in the digestive tract.
  • Individual Response: It’s important to note that not all individuals with IBD respond equally to mesalazine. Some patients may experience significant symptom relief and remission, while others may not respond as well, and alternative treatments may be necessary.

Overall, mesalazine pellets work by directly targeting and reducing inflammation in the digestive tract, making them a valuable treatment option for individuals with ulcerative colitis and certain cases of Crohn’s disease. However, the effectiveness of the medication can vary from person to person, and treatment should be guided by a healthcare provider’s recommendations and monitoring.

Benefits of Mesalazine Pellets:

  • Anti-Inflammatory: Mesalazine is an effective anti-inflammatory medication that targets the inflamed areas of the gastrointestinal tract. It helps reduce inflammation and alleviate symptoms associated with IBD.
  • Local Action: Mesalazine pellets are designed for local delivery, acting directly on the inflamed intestinal lining. This localized action minimizes systemic side effects that can occur with systemic medications.
  • Maintenance Therapy: Mesalazine is often used as a maintenance therapy to prevent disease relapses and maintain remission in patients with IBD.
  • Well-Tolerated: In general, mesalazine is well-tolerated by most patients, and serious side effects are relatively rare.
  • Minimal Systemic Absorption: Due to its topical action and limited systemic absorption, mesalazine is less likely to affect other organs and systems in the body compared to some other medications used in IBD treatment.

Common Side Effects of Mesalazine Pellets:

  • Gastrointestinal Symptoms: The most common side effects are related to the gastrointestinal tract and can include nausea, abdominal pain, diarrhea, and flatulence. These symptoms are usually mild and transient.
  • Headache: Some individuals may experience headaches while taking mesalazine.
  • Allergic Reactions: Although rare, allergic reactions to mesalazine can occur. If you develop symptoms such as rash, itching, swelling, severe dizziness, or difficulty breathing, seek immediate medical attention.
  • Liver Function Abnormalities: In rare cases, mesalazine can affect liver function, leading to elevated liver enzyme levels. Regular monitoring of liver function may be necessary during treatment.
  • Kidney Function Changes: Mesalazine can sometimes affect kidney function, leading to changes in kidney function tests. Regular monitoring of kidney function may also be required.
  • Pancreatitis: Although uncommon, mesalazine has been associated with pancreatitis (inflammation of the pancreas). Seek medical attention if you experience severe abdominal pain.
  • Blood Disorders: Rarely, mesalazine can affect blood cell counts, leading to conditions like anemia or a decrease in white blood cells.
  • Lung Problems: Mesalazine has been associated with lung reactions, including interstitial lung disease. Seek medical attention if you experience persistent cough, difficulty breathing, or chest pain.

It’s essential to discuss potential side effects and benefits with your healthcare provider before starting mesalazine pellets. Your doctor can help determine if mesalazine is the right choice for your specific condition and provide guidance on monitoring and managing any side effects that may occur during treatment. Additionally, individual responses to medications can vary, so close communication with your healthcare team is crucial for your overall well-being while on mesalazine therapy.

Frequently Asked Questions about Mesalazine pellets:

Certainly! Here are some frequently asked questions (FAQs) about Mesalazine pellets and their use:

  1. What is Mesalazine?

Mesalazine, also known as mesalazine, is a medication used to treat inflammatory bowel diseases (IBD) such as ulcerative colitis and Crohn’s disease.

  1. What are Mesalazine Pellets?

Mesalazine pellets are a pharmaceutical formulation of Mesalazine designed to provide controlled and targeted release of the medication in the gastrointestinal tract. They are used to treat IBD by reducing inflammation.

  1. How do Mesalazine Pellets work?

Mesalazine pellets work by delivering Mesalazine directly to inflamed areas of the digestive tract, where they help reduce inflammation and alleviate symptoms associated with IBD.

  1. What conditions are Mesalazine Pellets used to treat?

Mesalazine pellets are primarily used to treat ulcerative colitis and, in some cases, Crohn’s disease.

  1. What are the benefits of Mesalazine Pellets?

Benefits of Mesalazine pellets include their anti-inflammatory action, localized treatment, suitability for maintenance therapy, and minimal systemic side effects.

  1. What are the common side effects of Mesalazine Pellets?

Common side effects can include gastrointestinal symptoms (nausea, abdominal pain, diarrhea), headache, and, less commonly, liver or kidney function abnormalities.

  1. How should Mesalazine Pellets be taken?

The dosage and administration of Mesalazine pellets depend on the specific condition and severity. It’s crucial to follow your healthcare provider’s instructions.

  1. Are there any drug interactions with Mesalazine Pellets?

Yes, Mesalazine can interact with other medications. Inform your healthcare provider about all the medications you are taking to avoid potential interactions.

  1. Can Mesalazine Pellets be used during pregnancy and breastfeeding?

It’s essential to discuss the risks and benefits with your healthcare provider if you are pregnant or breastfeeding. In some cases, Mesalazine may be used if the potential benefits outweigh the risks.

  1. How long should Mesalazine Pellet treatment be continued?

The duration of treatment with Mesalazine pellets depends on your specific condition and response to therapy. Maintenance therapy may be recommended to prevent disease relapse.

  1. Can Mesalazine Pellets cure IBD?

Mesalazine can help manage symptoms and induce remission in IBD, but it is not a cure. IBD is a chronic condition, and long-term management is often necessary.

  1. Are there any lifestyle considerations while taking Mesalazine Pellets?

Your healthcare provider may recommend dietary and lifestyle modifications to complement your treatment. Staying hydrated and maintaining a healthy diet can be beneficial.

  1. What should I do if I miss a dose of Mesalazine Pellets?

If you miss a dose, take it as soon as you remember. However, if it’s close to the next scheduled dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose.

As Mesalazine Pellets Exporters; We can cater to export business queries from the following geographies. We are exporting our Mesalazine Pellets product in the Following Countries-

Russia and CIS Countries: Azerbaijan, Armenia, Belarus, Georgia, Kazakhstan, Kyrgyzstan, Moldova, Russia, Tajikistan, Turkmenistan, Uzbekistan and Ukraine

GCC/ Middle East Countries: Saudi Arabia, Yemen, Oman, Bahrain, UAE, Lebanon, Jordan, and Iraq.

African Countries: Nigeria, Tanzania, Sudan, Zambia, Benin, Angola, Liberia

Southeast Asia: Cambodia, Indonesia, Laos, Malaysia, Myanmar, Philippines, Singapore, Thailand, Vietnam, Brunei Darussalam

Other Asian Countries: Nepal, Myanmar, Malaysia, Cambodia, Bhutan, Sri Lanka, Mauritius

Mesalazine Pellets Regulatory Documents:

  • Certificate of Analysis (COA)
  • Method of Analysis (MOA)
  • Stability Data (Accelerated stability / Long-term stability / Zone 4b)
  • CTD Dossier / ACTD Dossiers / eCTD Dossiers
  • Certificate of Pharmaceuticals Product (COPP)
  • Free Sale Certificate (FSC)
Contact the most reliable manufacturer of Mesalazine Pellets, Taj Pharmaceuticals Limited to get bulk quantities at a reasonable price.

To Place Orders:

Direct line: +91 8448 444 095 / WhatsApp +91 74 0000 9975 / 74 0000 9976
E-Mail: info@tajpharma.com 
Toll free: 1-800-222-434 / Toll free: 1-800-222-825
General EPA BX: +91 22 2637 4592 / +91 22 2637 4593
Fax No: +91 22 2634 1274