GENERIC NAME OF THE MEDICINAL PRODUCT:

a) Melphalan Tablets USP 2mg
b) Melphalan Tablets USP 5mg

QUALITATIVE AND QUANTITATIVE COMPOSITION:

a) Melphalan Tablets USP 2 mg
Each film-coated tablet contains:
Melphalan USP……………2 mg
Excipients……………………q.s.
Colours: Titanium Dioxide USP

b) Melphalan Tablets USP 5 mg
Each film-coated tablet contains:
Melphalan USP……………5 mg
Excipients……………………q.s.
Colours: Iron Oxide of Red.

THERAPEUTIC INDICATIONS:

Melphalan is used to treat multiple myeloma (bone marrow cancer).

CAUTION & WARNING:

CAUTION: It is dangerous to take this preparation except under medical supervision.
WARNING: Cytotoxic Agent: To be sold by retail on the prescription of an oncologist/ Cancer Hospital/ Institution only.
Do not take in larger doses or more frequently or for a longer time than specifically directed by the physician. Periodic blood counts are necessary to determine proper dose and to avoid ill effects.
Dispense in glass tight and light resistant container as defined in the USP.
Keep out of reach and sight of children.
Swallow complete tablet, do not crush or chew.

STORAGE & DOSAGE:

Storage: Store at 2°C to 8°C (36° F to 46° F). Protect from light.
Dosage: As directed by Oncologist.
For Oral use. Read the package insert before use.

Melphalan Tablets USP 2mg Technical Specification:

Product Name:Melphalan Tablets USP 2mg
Brand Name:Melphalan
Strength:2mg, 5mg
Dosage Form:Film-coated Tablet
Packing:25s, 50s
Route of Administration:For Oral Use only.
Pack Insert/Leaflet:PIL (Patient Information Leaflet), SmPC (Summary Product Characteristics)
Regulatory Documents:COA, MOA, COPP, FSC, Stability Studies, GMP, CTD Dossier
Therapeutic use:Anti-Cancer
Indication: Melphalan is used to treat multiple myeloma (bone marrow cancer).
Storage:Store at 2°C to 8°C (36° F to 46° F). Protect from light.

GENERIC NAME OF THE MEDICINAL PRODUCT:

  • Melphalan Tablets USP 2mg

QUALITATIVE AND QUANTITATIVE COMPOSITION:

  • Melphalan Tablets USP 2 mg
    Each film-coated tablet contains:
    Melphalan USP……………2 mg
    Excipients……………………q.s.
    Colours: Titanium Dioxide USP

THERAPEUTIC INDICATIONS:

Melphalan is used to treat multiple myeloma (bone marrow cancer).

CAUTION & WARNING:

CAUTION: It is dangerous to take this preparation except under medical supervision.

WARNING: Cytotoxic Agent: To be sold by retail on the prescription of an oncologist/ Cancer Hospital/ Institution only.

Do not take in larger doses or more frequently or for a longer time than specifically directed by the physician. Periodic blood counts are necessary to determine proper dose and to avoid ill effects.

Dispense in glass tight and light resistant container as defined in the USP.

Keep out of reach and sight of children.

Swallow complete tablet, do not crush or chew.

STORAGE & DOSAGE:

Storage: Store at 2°C to 8°C (36° F to 46° F). Protect from light.

Dosage: As directed by Oncologist.

For Oral use. Read the package insert before use.

Why Taj pharmaceuticals?

Taj Pharmaceuticals stands out as a reputable choice for individuals seeking cancer treatment, particularly in the form of Melphalan Tablets. With a distinguished history in the pharmaceutical industry, Taj Pharma has consistently upheld pharmaceutical excellence. Their commitment to producing top-tier medications extends to Melphalan Tablets, reflecting their dedication to providing reliable and effective cancer treatment options. Specializing in oncology and cancer therapies, Taj Pharmaceuticals boasts a wealth of expertise in this field. This specialization underscores their unwavering commitment to enhancing the lives of cancer patients, as evidenced by the quality of Melphalan Tablets. The medication adheres to stringent quality control measures to ensure its safety and efficacy, meeting the highest standards in the industry. At the heart of Taj Pharma’s mission is a patient-centered approach. Melphalan Tablets are designed to offer not only effective cancer treatment but also compassionate care. The company prioritizes improved treatment outcomes and the overall quality of life for individuals grappling with cancer, emphasizing the human aspect of healthcare. Taj Pharmaceuticals’ global reach is a critical asset in the realm of cancer treatment. Their extensive distribution network ensures that medications like Melphalan Tablets are readily accessible to patients and healthcare providers worldwide. This global presence plays a pivotal role in the fight against cancer, ensuring that life-saving treatments are available when and where they are needed most. The company’s commitment to ongoing research and innovation in oncology is another hallmark of Taj Pharma. Their dedication drives the development of new and improved cancer therapies, including Melphalan Tablets, aimed at enhancing patient outcomes and pushing the boundaries of cancer care. Affordability is a key consideration for many patients facing cancer treatment. Taj Pharmaceuticals strives to provide cost-effective options, and Melphalan Tablets are a prime example. The medication strikes a balance between quality and affordability, supporting patients in their battle against cancer without compromising on the quality of care they receive. In summary, Taj Pharmaceuticals is a trusted and reputable choice for Melphalan Tablets, backed by a legacy of pharmaceutical excellence, a focus on cancer treatment expertise, rigorous quality control, patient-centered care, global accessibility, a commitment to research, and affordability. In the realm of cancer care, Taj Pharma stands as a beacon of hope, delivering high-quality medications that contribute to improved patient well-being and treatment outcomes.

What is Melphalan Tablets and its uses?

Melphalan Tablets are a medication used primarily in cancer therapy. The active ingredient in Melphalan Tablets is melphalan, which is a type of chemotherapy drug. Here are the primary uses of Melphalan Tablets:

  • Multiple Myeloma: Melphalan is commonly used in the treatment of multiple myeloma, a type of cancer that affects plasma cells in the bone marrow. It is often administered in combination with other medications as part of a comprehensive treatment plan.
  • Ovarian Cancer: Melphalan may also be used in the treatment of ovarian cancer, particularly when the disease is recurrent or has spread to other parts of the body. It can be part of a combination chemotherapy regimen.
  • Other Cancers: In some cases, Melphalan Tablets may be used off-label for other types of cancer, such as melanoma, neuroblastoma, and breast cancer, under the guidance of an oncologist.

Melphalan works by interfering with the DNA in cancer cells, preventing them from dividing and growing. This ultimately leads to the death of cancer cells. It’s important to note that Melphalan is a potent chemotherapy drug and is administered under the supervision of a healthcare professional in a clinical setting, such as a hospital or cancer treatment center. The specific dosage and treatment regimen are determined by an oncologist based on the type and stage of cancer, the patient’s overall health, and their individual response to the medication. Melphalan is typically taken orally in tablet form, making it convenient for patients undergoing cancer treatment.

How does Melphalan Tablets work?

Melphalan Tablets work as a chemotherapy medication to combat cancer by disrupting the growth and multiplication of cancer cells. Melphalan belongs to a class of drugs called alkylating agents, and its mechanism of action is primarily focused on interfering with the DNA (genetic material) within the cancer cells. Here’s how Melphalan works:

  • DNA Alkylation: Melphalan contains chemical groups called alkyl groups. When Melphalan is administered, it enters the bloodstream and is distributed throughout the body. Once inside cancer cells, it forms covalent bonds with various components of the DNA molecule.
  • DNA Cross-Linking: Melphalan’s alkyl groups can bind to two strands of the DNA double helix, creating cross-links between the strands. These cross-links can interfere with the normal separation of DNA strands during cell division, a crucial step in the replication of DNA.
  • DNA Damage: By forming cross-links and interfering with DNA replication, Melphalan induces damage to the DNA within cancer cells. This damage can prevent the cancer cells from dividing properly and may trigger programmed cell death (apoptosis).
  • Cell Cycle Arrest: Melphalan can also disrupt the cell cycle of cancer cells. It may halt the progression of cells through the various phases of the cell cycle, particularly the S phase, where DNA replication occurs.
  • Selective Toxicity: While Melphalan affects both cancer cells and some healthy cells, it has a stronger impact on rapidly dividing cancer cells. This selective toxicity is due to the fact that cancer cells typically divide more frequently than most normal cells.

The overall result of Melphalan’s actions is a reduction in the number of cancer cells and their ability to grow and spread. While Melphalan is effective against cancer, it can also affect healthy cells in the body, leading to potential side effects. Therefore, the dosage and administration of Melphalan are carefully monitored and adjusted by healthcare professionals to balance its anti-cancer effects with its impact on the patient’s overall health.

Benefits of Melphalan Tablets:

  • Effective Cancer Treatment: Melphalan is an effective chemotherapy medication used to treat multiple myeloma, ovarian cancer, and other cancer types. It plays a crucial role in slowing down or halting the growth of cancer cells, which can lead to tumor shrinkage and improved cancer management.
  • Combination Therapy: Melphalan is often used in combination with other chemotherapy drugs or treatments. This combination approach can enhance its effectiveness in treating cancer, especially in advanced or recurrent cases.
  • Preparation for Stem Cell Transplant: Melphalan is sometimes used as a conditioning regimen before a stem cell transplant in multiple myeloma and other diseases. It helps to suppress the patient’s immune system and destroy any remaining cancer cells before the transplant.
  • Palliative Care: In some cases where a cure is not possible, Melphalan can be used for palliative care. It aims to alleviate cancer-related symptoms, such as pain, discomfort, and anemia, improving the patient’s quality of life.

Side Effects of Melphalan Tablets:

  • Nausea and Vomiting: One of the common side effects of Melphalan is nausea and vomiting. Healthcare providers often prescribe anti-nausea medications to manage these symptoms.
  • Myelosuppression: Melphalan can suppress the bone marrow’s ability to produce blood cells, leading to myelosuppression. This can result in anemia, increased susceptibility to infections, and a reduced ability to form blood clots.
  • Fatigue: Many patients undergoing Melphalan treatment experience fatigue, which can significantly impact their daily activities. Adequate rest and proper nutrition are essential for managing this side effect.
  • Hair Loss: Melphalan can cause hair loss, although it is often temporary. The extent of hair loss can vary from person to person.
  • Gastrointestinal Issues: Diarrhea, constipation, and abdominal pain are possible gastrointestinal side effects of Melphalan.
  • Mouth Sores: Some patients may develop mouth sores during Melphalan treatment. Good oral hygiene practices can help prevent and manage this side effect.
  • Skin Changes: Melphalan can lead to changes in skin pigmentation and increased sensitivity to sunlight. Patients should use sunscreen and protective clothing when outdoors.
  • Hypersensitivity Reactions: In rare cases, hypersensitivity reactions, including rash, itching, swelling, and difficulty breathing, can occur. These reactions require immediate medical attention.
  • Liver Toxicity: Melphalan can affect liver function, leading to elevated liver enzymes. Regular monitoring of liver function is important during treatment.
  • Secondary Cancers: There is a slight risk of developing secondary cancers, such as leukemia, as a result of Melphalan treatment. However, the benefits of treating the primary cancer typically outweigh this risk.

It’s important to note that not all patients will experience these side effects, and their severity can vary. Healthcare providers closely monitor patients undergoing Melphalan treatment and take steps to manage and mitigate side effects as needed to ensure the best possible treatment outcome. Patients should communicate openly with their healthcare team about any side effects they experience during treatment.

Frequently Asked Questions About Melphalan Tablets?

Certainly, here are some frequently asked questions (FAQs) about Melphalan Tablets:

  1. What is Melphalan, and how does it work in cancer treatment?

Melphalan is a chemotherapy medication used to treat various types of cancer, including multiple myeloma and ovarian cancer. It works by interfering with the DNA of cancer cells, preventing their growth and division.

  1. What types of cancer are typically treated with Melphalan Tablets?

Melphalan is commonly used to treat multiple myeloma, a cancer of plasma cells in the bone marrow. It is also used in the treatment of ovarian cancer and may be considered for other cancer types.

  1. Is Melphalan used alone or in combination with other medications?

Melphalan is often used in combination with other chemotherapy drugs or treatments to enhance its effectiveness, especially in advanced or aggressive cancers.

  1. How is Melphalan administered?

Melphalan is typically administered orally in tablet form. The dosage and treatment regimen are determined by an oncologist based on the specific cancer diagnosis, stage, and individual patient factors.

  1. What are the common side effects of Melphalan Tablets?

Common side effects may include nausea, vomiting, myelosuppression (reduced blood cell counts), fatigue, hair loss, gastrointestinal issues, and mouth sores. Patients should discuss potential side effects with their healthcare team.

  1. Is Melphalan suitable for all cancer patients?

Melphalan may not be appropriate for all patients or cancer types. Its use depends on the specific diagnosis, stage, and individual patient factors. Consultation with an oncologist is essential to determine its suitability.

  1. Can Melphalan cure cancer?

While Melphalan can lead to remission in some cases, its primary goal is to manage cancer by slowing down or halting the growth of cancer cells. Its effectiveness varies depending on the type and stage of cancer.

  1. Are there any long-term risks associated with Melphalan treatment?

Some patients may face long-term risks, such as the development of secondary cancers (e.g., leukemia), as a result of Melphalan treatment. The benefits of treating the primary cancer are typically weighed against these risks.

  1. Is Melphalan safe during pregnancy or breastfeeding?

Melphalan can harm a developing fetus and should not be used during pregnancy. It is also not recommended during breastfeeding, as it may be excreted in breast milk.

  1. What should I do if I experience side effects during Melphalan treatment?

Patients should promptly report any side effects to their healthcare provider. Medical professionals can offer guidance on managing side effects and may adjust the treatment plan as needed.

Patients should engage in open communication with their oncologist to address any questions or concerns about Melphalan Tablets and their role in cancer treatment.

As Melphalan Tablets Exporters; We can cater to export business queries from the following geographies. We are exporting our Melphalan Tablets product in the Following Countries-

Russia and CIS Countries: Azerbaijan, Armenia, Belarus, Georgia, Kazakhstan, Kyrgyzstan, Moldova, Russia, Tajikistan, Turkmenistan, Uzbekistan and Ukraine

GCC/ Middle East Countries: Saudi Arabia, Yemen, Oman, Bahrain, UAE, Lebanon, Jordan, and Iraq.

African Countries: Nigeria, Tanzania, Sudan, Zambia, Benin, Angola, Liberia

Southeast Asia: Cambodia, Indonesia, Laos, Malaysia, Myanmar, Philippines, Singapore, Thailand, Vietnam, Brunei Darussalam

Other Asian Countries: Nepal, Myanmar, Malaysia, Cambodia, Bhutan, Sri Lanka, Mauritius

Melphalan Tablets Regulatory Documents:

  • Certificate of Analysis (COA)
  • Method of Analysis (MOA)
  • Stability Data (Accelerated stability / Long-term stability / Zone 4b)
  • CTD Dossier / ACTD Dossiers / eCTD Dossiers
  • Certificate of Pharmaceuticals Product (COPP)
  • Free Sale Certificate (FSC)
Contact the most reliable manufacturer of Melphalan Tablets, Taj Pharmaceuticals Limited, to get bulk quantities at a reasonable price.

To Place Orders:

Direct line: +91 8448 444 095 / WhatsApp +91 74 0000 9975 / 74 0000 9976
E-Mail: info@tajpharma.com 
Toll free: 1-800-222-434 / Toll free: 1-800-222-825
General EPA BX: +91 22 2637 4592 / +91 22 2637 4593
Fax No: +91 22 2634 1274