GENERIC NAME OF THE MEDICINAL PRODUCT:

A. Heparin Sodium Injection IP 5000 IU/5ml
B. Heparin Sodium Injection IP 25,000 IU/5ml

QUALITATIVE AND QUANTITATIVE COMPOSITION:

1. Heparin Sodium Injection IP 5000 IU/5ml
Each ml contains:
Heparin Sodium IP ………………1000IU
(Derived From Bovine Intestinal Mucosa)
Benzyl Alcohol IP…………………0.95%w/v
Water for Injection IP ………….q.s

2. Heparin Sodium Injection IP 10,000 IU/ml
Each ml contains:
Heparin Sodium IP ………………5000IU
(Derived From Bovine Intestinal Mucosa)
Benzyl Alcohol IP…………………0.95%w/v
Water for Injection IP ……………q.s

THERAPEUTIC INDICATIONS:

Heparin is used to prevent or treat certain blood vessel, heart, and lung conditions. Heparin is also used to prevent blood clotting during open-heart surgery, bypass surgery, kidney dialysis, and blood transfusions

DIRECTION OF USE:

For Intravenous, Intramuscular or Subcutaneous use only.
Refer insert for full prescribing information.

CAUTION & WARNING:

CAUTION:
Do not use if the solution is discolored or contains a precipitate.
This product contains benzyl alcohol and is not recommended for use in neonates.
Use only if seal is intact and undamaged.
Warning:
Not to be sold by retail without the prescription of a Registered Medical Practitioner.
NOT FOR LOCK FLUSH.

STORAGE & DOSAGE:

Storage: Store at 20°C to 25°C (68°F to 77°F).
Should be protected from freezing.
Protect from light.
Keep all medicines out of reach of children.
Dosage: As directed by the Physician.

Heparin Sodium Injection IP 25,000 IU/5ml Technical Specification:

Product Name:Heparin Sodium Injection IP
Brand Name:BEPRIN
Strength:25,000 IU/5ml,  5000 IU/5ml
Dosage Form:Liquid Injection (Sterile and Nonpyrogenic)
Packing:5000 IU /5ml (Packing: 1ml, 5ml, 10ml Ampoule/Vial)
25,000 IU/5ml (Packing: 5ml, 10ml, 30ml Ampoule/Vial)
Derived from:Bovine Intestinal Mucosa
Route of Administration:For I.M./I.V. or S.C. use Only
Pack Insert/Leaflet:PIL (Patient Information Leaflet), SmPC (Summary Product Characteristics)
Regulatory Documents:COA, MOA, COPP, FSC, Stability Studies, GMP, CTD Dossier
Therapeutic use:Anti-Coagulant
Indication: Heparin is used to prevent or treat certain blood vessel, heart, and lung conditions. Heparin is also used to prevent blood clotting during open-heart surgery, bypass surgery, kidney dialysis, and blood transfusions.
Storage:Store at 20°C to 25°C (68°F to 77°F). Do not freeze. Should be protected from freezing.

GENERIC NAME OF THE MEDICINAL PRODUCT:

  • Heparin Sodium Injection IP 25,000 IU/5ml (Beprin)

QUALITATIVE AND QUANTITATIVE COMPOSITION:

  • Heparin Sodium Injection IP 25,000 IU/5ml
    Each ml contains:
    Heparin Sodium IP…………………5000IU
    (Derived From Bovine Intestinal Mucosa)
    Benzyl Alcohol IP…………………0.95%w/v
    Water for Injection IP…………..q.s

THERAPEUTIC INDICATIONS:

Heparin is used to prevent or treat certain blood vessels, heart, and lung conditions. Heparin is also used to prevent blood clotting during open-heart surgery, bypass surgery, kidney dialysis, and blood transfusions.

DIRECTION OF USE:

For Intravenous, Intramuscular, or Subcutaneous use only.
Refer to insert for full prescribing information.

CAUTION & WARNING:

CAUTION:
Do not use if the solution is discolored or contains a precipitate.
This product contains benzyl alcohol and is not recommended for use in neonates.
Use only if seal is intact and undamaged.

Warning:
Not to be sold by retail without the prescription of a Registered Medical Practitioner.
NOT FOR LOCK FLUSH.

STORAGE & DOSAGE:

Storage: Store at 20°C to 25°C (68°F to 77°F).
Protect from light.
Should be protected from freezing.
Keep all medicines out of reach of children.
Dosage: As directed by the Physician.

Note: Origin: Bovine intestinal mucosa is a natural animal source. It is used in the pharmaceutical industry for the manufacture of the drug heparin. Hydrolyzed proteins are a coproduct of this pharmaceutical process.

Why Taj Pharmaceuticals?

Discover Taj Pharmaceuticals, a name synonymous with trust and innovation in the pharmaceutical world. Our Heparin Sodium Injection reflects our unwavering commitment to your health and safety. We have a long-standing history of producing pharmaceuticals that healthcare professionals rely on with confidence. At Taj Pharmaceuticals, we understand the critical importance of Heparin Sodium Injection in various medical applications, from preventing blood clots to aiding in surgical procedures. That’s why we leave no room for compromise in our production processes. Our cutting-edge manufacturing facilities adhere to the strictest quality control protocols, ensuring that each vial of Heparin Sodium Injection meets the highest industry standards.

Our commitment to innovation goes beyond quality assurance. We continuously invest in research and development to enhance the effectiveness and safety of our products. When you choose Taj Pharmaceuticals, you’re choosing a partner dedicated to advancing healthcare solutions to benefit both patients and medical practitioners. But it’s not just about the product; it’s about the people behind it. Our team of experts is driven by a passion for improving healthcare. We work tirelessly to provide you with pharmaceuticals that you can trust, giving you peace of mind when it matters most. Join the countless healthcare providers and patients who rely on Taj Pharmaceuticals for their Heparin Sodium Injection needs. Experience the difference that comes with a company deeply committed to your health and well-being. Taj Pharmaceuticals: Your partner for a healthier future.

What are Heparin Sodium Injections and their uses?

Heparin Sodium Injection is a medication that contains the active ingredient heparin, a naturally occurring substance in the body that helps prevent blood from clotting excessively. It is commonly used in medical settings for a variety of therapeutic and preventive purposes. Here are some of its primary uses:

  • Anticoagulation: Heparin Sodium Injection is often used to prevent or treat blood clots in conditions such as deep vein thrombosis (DVT), pulmonary embolism (PE), and atrial fibrillation. By inhibiting the formation of blood clots, heparin helps reduce the risk of serious complications like strokes, heart attacks, and organ damage.
  • Surgery: During certain surgical procedures, especially those involving the heart and blood vessels, heparin may be administered to prevent clot formation. This is critical in preventing blockages and maintaining blood flow during and after surgery.
  • Hemodialysis: Patients undergoing hemodialysis, a treatment for kidney failure, may receive heparin to prevent clotting within the dialysis machine and bloodlines, ensuring efficient blood purification.
  • Blood Sample Collection: Heparin is often used as an anticoagulant in blood collection tubes. It helps prevent blood from clotting during laboratory tests, allowing for accurate analysis of various blood parameters.
  • Arterial and Central Venous Catheters: Heparin can be used to flush and maintain the patency of arterial and central venous catheters to prevent clot formation and maintain proper functioning.
  • Miscarriage Prevention: In some cases, heparin may be prescribed to pregnant women with a history of recurrent miscarriages or certain clotting disorders to reduce the risk of blood clots in the placenta.
  • Extracorporeal Circulation: During procedures involving heart-lung machines or other extracorporeal circulation systems (common in cardiac surgery), heparin is used to prevent clotting within the equipment and maintain blood flow.

It’s important to note that heparin is a potent medication that requires careful monitoring of its dosage and effects, often through blood tests like the activated partial thromboplastin time (aPTT). The dose and duration of heparin therapy will vary based on the patient’s condition and medical history. Always follow your healthcare provider’s instructions and seek their guidance regarding its use and potential side effects.

How do Heparin Sodium Injections work?

Heparin Sodium Injection is an anticoagulant medication that works by interfering with the body’s natural blood clotting process. It primarily targets a clotting factor in the blood called thrombin and another factor called factor Xa. Here’s how Heparin Sodium Injection works:

  • Inhibition of Thrombin: Heparin binds to and enhances the activity of a molecule called antithrombin III (ATIII). Antithrombin III is a natural anticoagulant protein in the blood that inactivates several clotting factors, including thrombin. Thrombin is a key enzyme in the blood clotting cascade that converts soluble fibrinogen into insoluble strands of fibrin, forming a stable blood clot. By enhancing the activity of antithrombin III, heparin effectively blocks the activity of thrombin, preventing the formation of fibrin and inhibiting the formation of blood clots.
  • Inhibition of Factor Xa: Heparin also interferes with the activity of factor Xa, another essential clotting factor in the coagulation cascade. Factor Xa plays a crucial role in converting prothrombin to thrombin. By inhibiting factor Xa, heparin further reduces the ability of the blood to form clots.
  • Preventing Clot Propagation: By inhibiting both thrombin and factor Xa, heparin effectively prevents the further propagation or extension of existing blood clots. This property is particularly important in conditions where blood clots need to be treated or prevented, such as deep vein thrombosis (DVT), pulmonary embolism (PE), and certain heart conditions.
  • Anticoagulation Effect: Heparin acts rapidly, making it suitable for immediate anticoagulation needs, such as during surgery, when rapid prevention of clot formation is crucial.
  • Prevention of Clot Formation: Heparin also prevents the formation of new blood clots, making it valuable for prophylactic use in individuals at high risk for clot formation, such as those undergoing major surgery or those with certain medical conditions.

It’s important to note that heparin is typically administered under the supervision of healthcare professionals, either through intravenous (IV) infusion or subcutaneous injection, as its effects need to be carefully monitored. The dosage and duration of heparin therapy are determined by the patient’s specific medical condition and the risk of bleeding. Regular blood tests, such as the activated partial thromboplastin time (aPTT), are used to monitor the anticoagulant effect and adjust the dosage as needed to maintain a therapeutic balance between preventing clots and avoiding excessive bleeding.

Benefits of Heparin Sodium Injections:

  • Blood Clot Prevention: Heparin is highly effective in preventing and treating blood clots. It’s commonly used in situations where clot formation poses a significant risk, such as after surgery, during hospitalization, or in conditions like deep vein thrombosis (DVT) and pulmonary embolism (PE).
  • Quick Onset of Action: Heparin acts rapidly when administered intravenously, making it suitable for immediate anticoagulation needs, such as during surgery or in emergency situations.
  • Prophylactic Use: Heparin can be used prophylactically in patients at high risk of clot formation, helping prevent the development of blood clots in the first place
  • Management of Certain Medical Conditions: It’s used to manage medical conditions like atrial fibrillation, certain heart valve disorders, and kidney dialysis to prevent clotting in catheters and equipment.

Side Effects of Heparin Sodium Injections:

  • Bleeding: The most significant side effect of Heparin Sodium Injection is the risk of bleeding. While it’s effective at preventing clots, it can also hinder the body’s ability to form clots when needed, which can lead to excessive bleeding. This risk is monitored closely during treatment.
  • Heparin-Induced Thrombocytopenia (HIT): In some cases, heparin can cause a rare but serious condition called Heparin-Induced Thrombocytopenia. This is characterized by a significant drop in platelet count, which can lead to an increased risk of clotting.
  • Allergic Reactions: Allergic reactions to heparin are possible but uncommon. Symptoms may include hives, itching, swelling, and difficulty breathing. Severe allergic reactions are rare but can be life-threatening.
  • Osteoporosis: Long-term use of heparin may lead to a decrease in bone density (osteoporosis) in some individuals.
  • Skin Irritation: When administered subcutaneously, heparin can sometimes cause skin irritation, redness, or pain at the injection site.
  • Hair Loss: Prolonged use of heparin may result in hair loss (alopecia) in some individuals.

It’s important to use Heparin Sodium Injection under the guidance of a healthcare professional who can monitor your condition and adjust the dosage as needed to balance its benefits in preventing clot formation with the risk of bleeding or other side effects. The choice of anticoagulant and its duration of use will depend on your specific medical condition and individual risk factors. If you experience any unusual or severe side effects while using heparin, seek medical attention promptly.

Frequently Asked Questions About Heparin Solution Injection?

Certainly, here are some frequently asked questions (FAQs) about Heparin Solution Injection:

What is Heparin Solution Injection?

Heparin Solution Injection is a medication containing heparin, an anticoagulant, or blood-thinning agent. It is used to prevent and treat blood clots in various medical conditions.

What are the common uses of Heparin Solution Injection?

Heparin Solution Injection is commonly used to prevent and treat conditions such as deep vein thrombosis (DVT), pulmonary embolism (PE), atrial fibrillation, and during surgeries to prevent clot formation.

How is Heparin Solution Injection administered?

Heparin Solution Injection can be administered through various routes, including intravenously (IV) in hospital settings or subcutaneously (under the skin) for long-term use. The route and dosage depend on the medical condition being treated.

What are the potential side effects of Heparin Solution Injection?

Common side effects may include bleeding, pain or irritation at the injection site, and low platelet levels. Severe allergic reactions and a rare condition called HeparinInduced Thrombocytopenia (HIT) can also occur.

How is the dosage of Heparin Solution Injection determined?

The dosage of Heparin Solution Injection is determined by a healthcare provider based on the patient’s medical condition, weight, and other factors. It requires careful monitoring and adjustment to balance its anticoagulant effects with the risk of bleeding.

Are there any medications or conditions that interact with Heparin Solution Injection?

Yes, certain medications, such as nonsteroidal anti-inflammatory drugs (NSAIDs) and antiplatelet agents, can interact with Heparin Solution Injection. Conditions like bleeding disorders and recent surgeries may also affect its use.

Can pregnant or breastfeeding individuals use Heparin Solution Injection?

Heparin is often considered safe for use during pregnancy, especially for preventing blood clots in highrisk situations. It is generally considered safe during breastfeeding, but it’s important to consult with a healthcare provider.

How is the anticoagulant effect of Heparin Solution Injection monitored?

The anticoagulant effect is monitored using blood tests, such as the activated partial thromboplastin time (aPTT) or antifactor Xa assays. Regular testing helps ensure the medication’s effectiveness and safety.

What should I do if I miss a dose of Heparin Solution Injection?

It’s crucial to take Heparin Solution Injection as directed by your healthcare provider. If you miss a dose, contact your healthcare provider for guidance on how to proceed.

Can I drink alcohol while using Heparin Solution Injection?

It’s generally best to avoid excessive alcohol consumption while on anticoagulant therapy, as alcohol can increase the risk of bleeding and interact with some medications.

As Heparin Sodium Injections Exporters; We can cater to export business queries from the following geographies. We are exporting our Heparin Sodium Injections product to Following Countries-

Russia and CIS Countries: Azerbaijan, Armenia, Belarus, Georgia, Kazakhstan, Kyrgyzstan, Moldova, Russia, Tajikistan, Turkmenistan, Uzbekistan and Ukraine

GCC/ Middle East Countries: Saudi Arabia, Yemen, Oman, Bahrain, UAE, Lebanon, Jordan, and Iraq.

African Countries: Nigeria, Tanzania, Sudan, Zambia, Benin, Angola, Liberia

Southeast Asia: Cambodia, Indonesia, Laos, Malaysia, Myanmar, Philippines, Singapore, Thailand, Vietnam, Brunei Darussalam

Other Asian Countries: Nepal, Myanmar, Malaysia, Cambodia, Bhutan, Sri Lanka, Mauritius

Heparin Sodium Injections Regulatory Documents:

  • Certificate of Analysis (COA)
  • Method of Analysis (MOA)
  • Stability Data (Accelerated stability / Long-term stability / Zone 4b)
  • CTD Dossier / ACTD Dossiers / eCTD Dossiers
  • Certificate of Pharmaceuticals Product (COPP)
  • Free Sale Certificate (FSC)
Contact the most reliable manufacturer of Heparin Sodium Injections, Taj Pharmaceuticals Limited, to get bulk quantities at a reasonable price.

To Place Orders:

Direct line: +91 8448 444 095 / WhatsApp +91 74 0000 9975 / 74 0000 9976
E-Mail: info@tajpharma.com
Toll free: 1-800-222-434 / Toll free: 1-800-222-825
General EPA BX: +91 22 2637 4592 / +91 22 2637 4593
Fax No: +91 22 2634 1274