GENERIC NAME OF THE MEDICINAL PRODUCT:

A. Heparin Sodium Injection USP 1,000 IU/ml (Beprin)
B. Heparin Sodium Injection USP 5,000 IU/ml (Beprin)
C. Heparin Sodium Injection USP 10,000 IU/ml (Beprin)

QUALITATIVE AND QUANTITATIVE COMPOSITION:

A. Heparin Sodium Injection USP 1,000 IU/ml
Each ml contains:
Heparin Sodium USP……1000 IU
(From Porcine Intestinal Mucosa)
Sodium chloride…..........9mg
Methylparaben……………1.5mg
Propylparaben……………..0.15mg
Water for Injection USP…q.s

B. Heparin Sodium Injection USP 5,000 IU/ml
Each ml contains:
Heparin Sodium USP ……5000 IU
(From Porcine Intestinal Mucosa)
Sodium chloride….......9mg
Methylparaben....……..1.5mg
Propylparaben…....…….0.15mg
Water for Injection USP …q.s


C. Heparin Sodium Injection USP 10,000 IU/ml
Each ml contains:
Heparin Sodium USP ……10,000 IU
(From Porcine Intestinal Mucosa)
Sodium chloride….......9mg
Methylparaben…....…..1.5mg
Propylparaben…....…….0.15mg
Water for Injection USP …q.s

THERAPEUTIC INDICATIONS:

Heparin is used to prevent or treat certain blood vessel, heart, and lung conditions. Heparin is also used to prevent blood clotting during open-heart surgery, bypass surgery, kidney dialysis, and blood transfusions.

DIRECTION OF USE:

For Intravenous, Intramuscular or Subcutaneous use only.
Refer insert for full prescribing information.

CAUTION & WARNING:

CAUTION: The injection should not be used It contains visible particulate matter.
NOT FOR LOCK FLUSH.
Not to be used in newly born or premature infants.
FLIP-OFF SEAL IS PROVIDED FOR TAMPER EVIDENCE.
Use only if seal is intact and undamaged.
Warning: Not to be sold by retail without the prescription of a Registered Medical Practitioner.

STORAGE & DOSAGE:

Storage: Store at 20°C to 25°C (68°F to 77°F).
Should be protected from freezing.
Keep all medicines out of reach of children.
Dosage: As directed by the Physician.
Note:
Origin: porcine intestinal mucosa is a natural animal source. It is used in the pharmaceutical industry for the manufacture of the drug heparin. Hydrolysed proteins are a coproduct of this pharmaceutical process.

Heparin Sodium Injection USP 5,000 IU/ml Technical Specification:

Product Name:Heparin Sodium Injection USP
Brand Name:BEPRIN
Strength:(1000 IU/ml),  (5000 IU/ml),  (10,000 IU/ml)
Dosage Form:Liquid Injection (Sterile and Nonpyrogenic)
Packing:1000 IU/ml (Packing: 1ml, 2ml, 5ml, 10ml, 30ml Ampoule/Vial)
5000 IU /ml (Packing: 1ml, 5ml, 10ml Ampoule/Vial)
10,000 IU/ml (Packing: 4ml Ampoule/Vial)
Derived from:Porcine Intestinal Mucosa
Route of Administration:For I.M./I.V. or S.C. use Only
Pack Insert/Leaflet:PIL (Patient Information Leaflet), SmPC (Summary Product Characteristics)
Regulatory Documents:COA, MOA, COPP, FSC, Stability Studies, GMP, CTD Dossier
Therapeutic use:Anti-Coagulant
Indication: Heparin is used to prevent or treat certain blood vessel, heart, and lung conditions. Heparin is also used to prevent blood clotting during open-heart surgery, bypass surgery, kidney dialysis, and blood transfusions.
Storage:Store at 20°C to 25°C (68°F to 77°F). Should be protected from freezing.

GENERIC NAME OF THE MEDICINAL PRODUCT:

  • Heparin Sodium Injection USP 5,000 IU/ml (Beprin)

QUALITATIVE AND QUANTITATIVE COMPOSITION:

  • Heparin Sodium Injection USP 5,000 IU/ml
    Each ml contains:
    Heparin Sodium USP…….5000 IU
    (From Porcine Intestinal Mucosa)
    Sodium chloride………….9mg
    Methylparaben……………1.5mg
    Propylparaben……………..0.15mg
    Water for Injection USP…q.s

THERAPEUTIC INDICATIONS:

Heparin is used to prevent or treat certain blood vessel, heart, and lung conditions. Heparin is also used to prevent blood clotting during open-heart surgery, bypass surgery, kidney dialysis, and blood transfusions.

DIRECTION OF USE:

For Intravenous, Intramuscular or Subcutaneous use only.
Refer insert for full prescribing information.

CAUTION & Warning:

CAUTION: The injection should not be used It contains visible particulate matter.
Not to be used in newly born or premature infants.
NOT FOR LOCK FLUSH.
FLIP-OFF SEAL IS PROVIDED FOR TAMPER EVIDENCE.

Warning: Not to be sold by retail without the prescription of a Registered Medical Practitioner.

STORAGE & DOSAGE:

Storage: Store at 20°C to 25°C (68°F to 77°F).
Should be protected from freezing.
Keep all medicines out of reach of children.

Dosage: As directed by the Physician.

Note: Origin: porcine intestinal mucosa is a natural animal source. It is used in the pharmaceutical industry for the manufacture of the drug heparin. Hydrolysed proteins are a coproduct of this pharmaceutical process.

Why Taj Pharmaceuticals?

At Taj Pharma, our Heparin Sodium Injection stands out as the preferred choice for a multitude of compelling reasons. First and foremost, our commitment to maintaining uncompromising quality sets us apart. We subject every vial of Heparin Sodium to stringent quality control measures at every stage of production, ensuring that it not only meets but exceeds international quality standards. Patient safety is paramount to us, and we maintain strict protocols to prevent contamination and impurities, guaranteeing the safety of each dose. In addition to quality and safety, our Heparin Sodium Injection has a track record of proven efficacy in preventing and treating blood clots. Healthcare providers and patients trust our product for its reliability and consistent effectiveness. Affordability is another hallmark of Taj Pharma’s offerings. We firmly believe that access to high-quality medications should be affordable for all, and our competitive pricing reflects this commitment.

Taj Pharma’s global reputation in the pharmaceutical industry is built on its dedication to excellence. Our experience and innovation combine to continually enhance our products and processes, keeping us at the forefront of medical advancements. Furthermore, our dedicated customer support team is readily available to address any questions or concerns, ensuring your satisfaction with our products and services. Sustainability is a core value at Taj Pharma, and we’re committed to environmentally responsible practices in pharmaceutical manufacturing, striving to minimize our environmental footprint and contribute to a healthier planet. In conclusion, when you choose Taj Pharma for Heparin Sodium Injection, you’re making a choice aligned with trust, quality, safety, affordability, and innovation. We are your dependable partner on the journey to better health.

What is Heparin Sodium Injection and its uses:

Heparin Sodium Injection is a medication that contains the active ingredient heparin, which is a naturally occurring anticoagulant (blood thinner). It is used in medical settings for a variety of purposes, primarily related to preventing and treating blood clots. Here are some of its common uses:

  • Preventing Blood Clots: Heparin Sodium Injection is often used to prevent the formation of blood clots in various medical situations. This includes preventing deep vein thrombosis (DVT), which can occur after surgery, during hospitalization, or in conditions where a person is immobile for extended periods.
  • Treating Blood Clots: Heparin can also be used to treat existing blood clots, such as those in deep veins (deep vein thrombosis) or in the lungs (pulmonary embolism). By preventing the clot from growing larger and reducing the risk of new clots forming, heparin can help prevent serious complications.
  • During Surgery: Heparin Sodium Injection is used during certain surgical procedures, particularly those involving blood vessels or the heart. It helps prevent clot formation during the operation, reducing the risk of complications like stroke or heart attack.
  • Hemodialysis: Individuals undergoing hemodialysis, a procedure that filters waste products and excess fluids from the blood when the kidneys are not functioning properly, may receive heparin to prevent clotting in the dialysis machine.
  • Blood Samples: In medical settings, heparin may be used to prevent blood samples from clotting. This is important for accurate laboratory testing.
  • Miscarriage Prevention: In some cases, heparin may be prescribed to pregnant women who have a history of recurrent miscarriages or specific clotting disorders to reduce the risk of blood clots that can affect the pregnancy.

It’s important to note that Heparin Sodium Injection is a prescription medication and should only be used under the guidance and supervision of a qualified healthcare professional. The dosage and duration of treatment with heparin will vary depending on the specific medical condition being treated and the patient’s individual needs. Additionally, heparin can have side effects and may interact with other medications, so it’s crucial to follow your healthcare provider’s recommendations and report any unusual symptoms or reactions.

How Does Heparin Sodium Injection Work?

Heparin Sodium Injection works primarily as an anticoagulant, meaning it prevents the formation and growth of blood clots in the circulatory system. It does so by interfering with the body’s blood clotting process, specifically targeting several steps in the coagulation cascade. Here’s how Heparin Sodium Injection works:

  • Inhibition of Thrombin: Thrombin is a key enzyme in the blood clotting process. Heparin binds to antithrombin III, a natural protein in the blood that inhibits thrombin and other clotting factors. When heparin binds to antithrombin III, it enhances the inhibition of thrombin, effectively reducing its ability to convert fibrinogen into fibrin. Fibrin is a protein that forms the framework of a blood clot.
  • Inhibition of Other Clotting Factors: In addition to thrombin, heparin also inhibits other clotting factors such as factor Xa and factor IXa. These factors play essential roles in the coagulation cascade, which is a series of enzymatic reactions that lead to the formation of a blood clot. By inhibiting these factors, heparin prevents the cascade from progressing and the blood from clotting excessively.
  • Preventing Clot Formation: By inhibiting thrombin and other clotting factors, heparin effectively reduces the ability of the blood to form clots. It keeps blood in a more liquid state, which is important in preventing or treating conditions associated with abnormal blood clotting, such as deep vein thrombosis (DVT), pulmonary embolism (PE), and certain cardiovascular procedures.

Heparin Sodium Injection acts relatively quickly and is typically administered through injection, either into a vein (intravenous) or under the skin (subcutaneous). The dosage and administration method may vary depending on the specific medical condition being treated and the patient’s individual factors. It’s important for healthcare professionals to carefully monitor the patient’s response to heparin to ensure that the desired anticoagulant effect is achieved without excessive bleeding or other complications.

Benefits and Side Effects of Heparin Sodium Injection:

Heparin Sodium Injection offers several benefits in medical settings for preventing and treating blood clots, but it can also be associated with certain side effects. It’s important to understand both its benefits and potential risks. Here’s an overview:

Benefits of Heparin Sodium Injection:

  • Anticoagulant Effect: The primary benefit of Heparin Sodium Injection is its ability to prevent and treat blood clots. It is used in various medical conditions and surgical procedures to reduce the risk of thrombosis (clot formation) in veins and arteries. This can help prevent serious conditions like deep vein thrombosis (DVT) and pulmonary embolism (PE).
  • Immediate Action: Heparin acts relatively quickly, making it suitable for situations where rapid anticoagulation is needed, such as during certain surgeries or when treating acute thrombotic events.
  • Versatility: Heparin can be administered intravenously (IV) or subcutaneously (under the skin), making it versatile and adaptable to different medical situations and patient needs.

Side Effects of Heparin Sodium Injection:

  • Bleeding: One of the most significant side effects of heparin is the risk of bleeding. Heparin reduces the blood’s ability to clot, which can lead to bleeding at the injection site, nosebleeds, gastrointestinal bleeding, or even more severe bleeding in some cases.
  • Heparin-Induced Thrombocytopenia (HIT): In some individuals, heparin can cause a condition called heparin-induced thrombocytopenia, where the number of platelets in the blood decreases significantly. This can increase the risk of abnormal clotting and lead to complications.
  • Hemorrhage: In rare cases, heparin can lead to serious hemorrhagic events, such as intracranial bleeding (bleeding within the brain), which can be life-threatening.
  • Osteoporosis: Long-term use of heparin may be associated with bone loss (osteoporosis), particularly in high doses or with prolonged use.
  • Allergic Reactions: Some individuals may experience allergic reactions to heparin, which can manifest as skin rashes, itching, or more severe allergic responses.
  • Injection Site Reactions: When administered subcutaneously, heparin may cause pain, redness, or irritation at the injection site.
  • Hair Loss: Prolonged use of heparin, particularly in high doses, has been associated with hair loss in some patients.

It’s essential for healthcare providers to carefully monitor patients receiving Heparin Sodium Injection to manage its anticoagulant effect effectively while minimizing the risk of bleeding or other adverse events. The dosage and duration of treatment are tailored to the specific medical condition and individual patient factors. Patients should communicate any unusual symptoms or side effects to their healthcare team promptly.

Frequently Asked Questions About Heparin Sodium Injection:

Certainly, here are some frequently asked questions (FAQs) about Heparin Sodium Injection:

  1. What is Heparin Sodium Injection used for?

Heparin Sodium Injection is primarily used as an anticoagulant to prevent and treat blood clots in various medical conditions, including deep vein thrombosis (DVT), pulmonary embolism (PE), and during certain surgeries.

  1. How does Heparin Sodium Injection work?

Heparin works by inhibiting key blood clotting factors, such as thrombin and factor Xa, preventing the formation and growth of blood clots.

  1. Is Heparin Sodium Injection safe?

When used under the guidance of a healthcare professional, Heparin Sodium Injection is generally safe and effective. However, it does carry the risk of bleeding and other side effects, which should be closely monitored.

  1. What are the potential side effects of Heparin Sodium Injection?

Common side effects include bleeding, bruising, and pain at the injection site. More serious side effects may include heparin induced thrombocytopenia (HIT), allergic reactions, and hemorrhage.

  1. How is Heparin Sodium Injection administered?

Heparin can be administered either intravenously (IV) or subcutaneously (under the skin), depending on the specific medical condition and healthcare provider’s recommendations.

  1. Can Heparin Sodium Injection be self-administered at home?

In some cases, healthcare providers may prescribe Heparin Sodium for self-administration at home for certain medical conditions, with proper training and guidance.

  1. How is the dosage of Heparin Sodium Injection determined?

The dosage is determined by the patient’s weight, medical condition, and the desired level of anticoagulation. Healthcare professionals carefully calculate the appropriate dose.

  1. Are there any dietary restrictions while taking Heparin Sodium Injection?

There are no specific dietary restrictions associated with Heparin Sodium Injection, but patients should discuss their diet and any potential interactions with their healthcare provider.

  1. Can Heparin Sodium Injection be used during pregnancy?

Heparin is sometimes prescribed during pregnancy to treat or prevent blood clots in women with certain medical conditions. However, its use during pregnancy should be carefully monitored by a healthcare provider.

  1. What should I do if I experience bleeding or other adverse effects while on Heparin Sodium Injection?

If you experience unusual bleeding or any severe side effects, seek immediate medical attention and contact your healthcare provider.

  1. Can Heparin Sodium Injection interact with other medications?

Heparin can interact with some medications, so it’s essential to inform your healthcare provider of all the medications, supplements, and herbal products you are taking.

  1. Is Heparin Sodium Injection safe for children and infants?

Heparin may be used in pediatric populations, but the dosing and administration should be carefully tailored to the child’s weight and medical condition under the guidance of a pediatric specialist.

It’s crucial for patients to discuss any questions or concerns about Heparin Sodium Injection with their healthcare provider to ensure safe and effective treatment.

As Heparin Sodium Injection Exporters; We can cater to export business queries from the following geographies. We are exporting our Heparin Sodium Injection product in the Following Countries-

Russia and CIS Countries: Azerbaijan, Armenia, Belarus, Georgia, Kazakhstan, Kyrgyzstan, Moldova, Russia, Tajikistan, Turkmenistan, Uzbekistan and Ukraine

GCC/ Middle East Countries: Saudi Arabia, Yemen, Oman, Bahrain, UAE, Lebanon, Jordan, and Iraq.

African Countries: Nigeria, Tanzania, Sudan, Zambia, Benin, Angola, Liberia

Southeast Asia: Cambodia, Indonesia, Laos, Malaysia, Myanmar, Philippines, Singapore, Thailand, Vietnam, Brunei Darussalam

Other Asian Countries: Nepal, Myanmar, Malaysia, Cambodia, Bhutan, Sri Lanka, Mauritius

Heparin Sodium Injection Regulatory Documents:

  • Certificate of Analysis (COA)
  • Method of Analysis (MOA)
  • Stability Data (Accelerated stability / Long-term stability / Zone 4b)
  • CTD Dossier / ACTD Dossiers / eCTD Dossiers
  • Certificate of Pharmaceuticals Product (COPP)
  • Free Sale Certificate (FSC)
Contact the most reliable manufacturer of Heparin Sodium Injection, Taj Pharmaceuticals Limited, to get bulk quantities at a reasonable price.

To Place Orders:

Direct line: +91 8448 444 095 / WhatsApp +91 74 0000 9975 / 74 0000 9976
E-Mail: info@tajpharma.com 
Toll free: 1-800-222-434 / Toll free: 1-800-222-825
General EPA BX: +91 22 2637 4592 / +91 22 2637 4593
Fax No: +91 22 2634 1274