GENERIC NAME OF THE MEDICINAL PRODUCT:

Enteric Coated Pantoprazole Sodium and Domperidone Sustained Release Capsules 40mg/30mg

QUALITATIVE AND QUANTITATIVE COMPOSITION:

Enteric Coated Pantoprazole Sodium and Domperidone Sustained Release Capsules 40mg/30mg
Each Hard-gelatin capsules contains:
Pantoprazole Sodium I.P.
Eq. to Pantoprazole …………………40mg
(As enteric coated pellets)
Domperidone I.P. …………………30mg
(As sustained release pellets)
Excipients……………………………. q.s.
Approved Colours used in empty capsule shell.

THERAPEUTIC INDICATIONS:

Pantoprazole + Domperidone is a combination of two medicines: Domperidone and Pantoprazole. This combination is used to treat acidity, heartburn or Gastroesophageal Reflux Disease (GERD); a condition where the acid in the stomach flows back up into the food pipe (esophagus).

CAUTION & SCHEDULE:

CAUTION: SWALLOW WHOLE DO NOT CHEW OR CRUSH
They should be swallowed whole with water.
Read enclosed leaflet before use.
SCHEDULE: SCHEDULE H PRESCRIPTION DRUG-CAUTION: To be sold by retail on the prescription of a Registered Medical Practitioner only.
KEEP MEDICINE OUT OF REACH OF CHILDREN.

STORAGE & DOSAGE:

Storage: Store below 25°C in a dry place.
Do not freeze.
Keep the container tightly closed in order to protect from moisture.
Dosage: As directed by the physician.
Attach dispensing label as per end country.

Enteric Coated Pantoprazole Sodium and Domperidone Sustained Release Capsules 40mg/30mg Technical Specification:

Product Name:
Enteric Coated Pantoprazole Sodium and Domperidone Sustained Release Capsules
Brand Name:Pantotaj DSR
Strength:40mg/30mg
Dosage Form:Capsule (Hard-Gelatine)
Route of Administration:Via oral Route
Packing:10s, 100s
Pack Insert/Leaflet:PIL (Patient Information Leaflet)
Regulatory Documents:COA, MOA, Stability Studies, GMP
Therapeutic use:Antiulcer
Indication: Pantoprazole + Domperidone is a combination of two medicines: Domperidone and Pantoprazole. This combination is used to treat acidity, heartburn or Gastroesophageal Reflux Disease (GERD); a condition where the acid in the stomach flows back up into the food pipe (esophagus).
Storage:Store below 25°C in a dry place. Do not freeze. Keep the container tightly closed in order to protect from moisture.

GENERIC NAME OF THE MEDICINAL PRODUCT:

  • Enteric Coated Pantoprazole Sodium and Domperidone Sustained Release Capsules 40mg/30mg

QUALITATIVE AND QUANTITATIVE COMPOSITION:

  • Enteric Coated Pantoprazole Sodium and Domperidone Sustained Release Capsules 40mg/30mg
    Each Hard-gelatin capsules contains:
    Pantoprazole Sodium I.P.
    Eq. to Pantoprazole …………………40mg
    (As enteric coated pellets)
    Domperidone I.P. …………………30mg
    (As sustained release pellets)
    Excipients……………………………. q.s.
    Approved Colours used in empty capsule shell.

THERAPEUTIC INDICATIONS:

Pantoprazole + Domperidone is a combination of two medicines: Domperidone and Pantoprazole. This combination is used to treat acidity, heartburn or Gastroesophageal Reflux Disease (GERD); a condition where the acid in the stomach flows back up into the food pipe (esophagus).

CAUTION & schedule:

CAUTION:  SWALLOW WHOLE DO NOT CHEW OR CRUSH

They should be swallowed whole with water.

Read enclosed leaflet before use.

schedule: schedule H PRESCRIPTION DRUG-CAUTION: To be sold by retail on the prescription of a Registered Medical Practitioner only.

Keep medicine out of reach of children.

STORAGE & DOSAGE:

Storage:  Store below 25°C in a dry place.  Do not freeze.  Keep the container tightly closed in order to protect from moisture.

Dosage: As directed by the physician.

Attach dispensing label as per end country.

Why Taj Pharmaceuticals?

Taj Pharmaceuticals stands out as a trusted choice for Pantoprazole Sodium and Domperidone Capsules due to its unwavering commitment to pharmaceutical excellence. With a longstanding reputation in the industry, Taj Pharmaceuticals has earned the trust of healthcare professionals and patients alike. Their dedication to producing high-quality medications ensures that individuals dealing with acid-related digestive issues receive effective and safe treatments. One of Taj Pharmaceuticals’ notable strengths is its expertise in gastrointestinal health. They specialize in medications related to digestive well-being, making them a go-to option for those seeking relief from acid-related digestive problems. Their extensive knowledge in this field allows for tailored solutions that address the specific needs of individuals, providing effective relief. Taj Pharmaceuticals’ commitment to global accessibility is another significant aspect. Acid-related digestive conditions affect individuals worldwide, and Taj Pharmaceuticals ensures that Pantoprazole Sodium and Domperidone Capsules are readily available to people and healthcare systems across the globe. This global reach is vital in addressing the widespread prevalence of acid-related digestive issues. A patient-centric approach is central to Taj Pharmaceuticals’ philosophy. They prioritize the comfort and well-being of individuals grappling with acid-related digestive problems. Their medications are not only effective but also designed to minimize potential side effects, ultimately enhancing the quality of life for patients. Taj Pharmaceuticals offers a comprehensive portfolio of gastrointestinal medications, including Pantoprazole Sodium and Domperidone Capsules. This extensive range allows healthcare providers to choose the most suitable treatment options for their patients, ensuring that individual digestive needs are met effectively. Quality assurance is paramount in Taj Pharmaceuticals’ operations. They adhere to stringent quality control measures to guarantee that Pantoprazole Sodium and Domperidone Capsules meet the highest pharmaceutical standards. This commitment to quality and safety underscores their dedication to providing reliable and effective solutions for acid-related digestive issues. Lastly, affordability is a critical consideration in healthcare. Taj Pharmaceuticals strives to offer cost-effective solutions for managing gastrointestinal health, ensuring that individuals can access the necessary treatment without compromising quality. Taj Pharmaceuticals’ reputation for pharmaceutical excellence, gastrointestinal expertise, global accessibility, patient-centric approach, comprehensive portfolio, quality assurance, and affordability make them a trusted and dependable choice for Pantoprazole Sodium and Domperidone Capsules. When seeking relief from acid-related digestive problems, individuals and healthcare providers can confidently rely on Taj Pharmaceuticals for personalized, effective, and safe solutions that prioritize gastrointestinal well-being.

What is Pantoprazole Sodium and Domperidone Capsules and its use?

Pantoprazole Sodium and Domperidone Capsules are a medication that combines two active ingredients: pantoprazole sodium and domperidone. This combination is used to treat various gastrointestinal conditions, and here are their primary uses:

  1. Pantoprazole Sodium (Proton Pump Inhibitor PPI): Pantoprazole is a proton pump inhibitor (PPI) that reduces the production of stomach acid.

Uses:

  • Gastric Acid Disorders: Pantoprazole is primarily prescribed for conditions characterized by excess stomach acid production, such as gastroesophageal reflux disease (GERD), erosive esophagitis, and Zollinger-Ellison syndrome.
  • Ulcers: It is used to heal and prevent ulcers in the stomach and duodenum, including peptic ulcers and stress ulcers.
  • Helicobacter pylori Eradication: Pantoprazole is sometimes part of a combination therapy to eradicate Helicobacter pylori bacteria, which can contribute to stomach ulcers.
  1. Domperidone (Prokinetic Agent): Domperidone is a prokinetic agent that enhances gastrointestinal motility and facilitates the movement of food through the digestive tract.

Uses:

  • Gastrointestinal Symptoms: Domperidone is used to relieve symptoms like nausea and vomiting, especially in cases of functional dyspepsia and gastroesophageal reflux.
  • Delayed Gastric Emptying: It may be prescribed to accelerate gastric emptying, which can alleviate symptoms of bloating and discomfort.

Combination Use: When used together in Pantoprazole Sodium and Domperidone Capsules, pantoprazole reduces stomach acid production, which can help alleviate acidrelated symptoms and protect the digestive lining. Domperidone complements this action by promoting the efficient movement of food through the digestive tract and relieving symptoms like nausea and discomfort. It’s important to note that the use of Pantoprazole Sodium and Domperidone Capsules should be determined by a healthcare provider based on an individual’s specific medical condition and needs. This combination medication can provide relief from a range of gastrointestinal issues by addressing both excessive acid production and digestive motility concerns.

How do Pantoprazole Sodium and Domperidone Capsules work?

Pantoprazole Sodium and Domperidone Capsules work through the combined actions of their two active ingredients: pantoprazole sodium and domperidone. Each ingredient plays a distinct role in addressing gastrointestinal issues:

  • Pantoprazole Sodium (Proton Pump Inhibitor PPI):
    Pantoprazole sodium is a proton pump inhibitor (PPI), a class of drugs that reduces the production of stomach acid.
    It works by selectively inhibiting the proton pumps in the stomach lining, specifically the hydrogen potassium ATPase enzyme. This enzyme is responsible for the final step in the secretion of gastric acid.
    By blocking the action of these pumps, pantoprazole effectively reduces the production of gastric acid, leading to a decrease in the acidity of the stomach contents.
  • Domperidone (Prokinetic Agent):
    Domperidone is a prokinetic agent that enhances gastrointestinal motility and facilitates the movement of food and gastric contents through the digestive tract.
    It works by blocking the action of dopamine in the gut. Dopamine normally inhibits the release of acetylcholine, a neurotransmitter that stimulates smooth muscle contractions in the digestive tract.
    By inhibiting dopamine’s effects, domperidone promotes the release of acetylcholine, leading to increased contractions of the stomach and small intestine muscles. This enhances gastric emptying and accelerates the passage of food through the digestive system.

Combination Synergy: The combination of pantoprazole and domperidone in a single capsule offers a comprehensive approach to managing gastrointestinal issues. Here’s how they work together:
Pantoprazole reduces stomach acid production, helping alleviate symptoms related to excess acidity, such as heartburn and acid reflux.
Domperidone enhances gastrointestinal motility and reduces symptoms like bloating, discomfort, and early satiety.

Use in Gastrointestinal Disorders: For conditions like gastroesophageal reflux disease (GERD), the reduction in acid production by pantoprazole helps heal and prevent damage to the esophagus, while domperidone aids in reducing symptoms like nausea and discomfort. In cases of ulcers, pantoprazole promotes ulcer healing by decreasing acid exposure to the ulcerated area. Domperidone is particularly beneficial for individuals with delayed gastric emptying, as it accelerates the movement of gastric contents, relieving symptoms associated with delayed motility. The combination of these two active ingredients addresses both acid related issues and gastrointestinal motility problems, providing effective relief for a range of gastrointestinal conditions. However, it’s crucial to use Pantoprazole Sodium and Domperidone Capsules under the guidance of a healthcare provider to ensure safe and appropriate treatment.

Benefits of Pantoprazole Sodium and Domperidone Capsules:

  • Effective Acid Reflux Relief: These capsules are highly effective in reducing excess stomach acid production, making them particularly beneficial for individuals with gastroesophageal reflux disease (GERD). By lowering acid levels, they help alleviate symptoms like heartburn, acid regurgitation, and chest pain.
  • Healing and Prevention of Ulcers: Pantoprazole Sodium and Domperidone Capsules can aid in the healing of peptic ulcers in the stomach and duodenum. They also work as a preventive measure to reduce the recurrence of ulcers, providing relief from ulcer-related symptoms such as abdominal pain and discomfort.
  • Symptom Relief in Functional Dyspepsia: For individuals with functional dyspepsia, these capsules can help relieve symptoms like bloating, early satiety, and abdominal discomfort by improving digestive motility and reducing acid-related issues.
  • Nausea and Vomiting Management: Domperidone, a prokinetic agent in these capsules, is effective in managing nausea and vomiting, making them suitable for individuals experiencing these symptoms, especially when associated with conditions like GERD or delayed gastric emptying.
  • Helicobacter pylori Eradication: When prescribed as part of a combination therapy, Pantoprazole Sodium and Domperidone Capsules can contribute to the eradication of Helicobacter pylori bacteria, which is associated with peptic ulcers and other gastric issues.

Side Effects of Pantoprazole Sodium and Domperidone Capsules:

  • Nausea and Vomiting: While domperidone is used to manage nausea and vomiting, it can occasionally cause these symptoms as side effects, especially when used at higher doses.
  • Gastrointestinal Disturbances: Some individuals may experience gastrointestinal side effects such as diarrhea, constipation, or abdominal pain.
  • Headache: Headache is a possible side effect of these capsules, although it is generally mild and temporary.
  • Dizziness: Rarely, domperidone may cause dizziness, which can affect some individuals.
  • Allergic Reactions: In very rare cases, individuals may experience allergic reactions to the medication, characterized by skin rash, itching, or swelling.
  • Cardiac Arrhythmias (Rare): Domperidone can affect the electrical activity of the heart in some cases, potentially leading to cardiac arrhythmias. It’s essential to use this medication under medical supervision and as prescribed.
  • Changes in Liver Enzymes (Rare): In rare instances, pantoprazole can cause changes in liver enzyme levels. Routine monitoring may be necessary.

It’s crucial to take Pantoprazole Sodium and Domperidone Capsules as prescribed by a healthcare provider and to report any severe or persistent side effects promptly. While these capsules offer significant benefits in managing acid-related digestive issues, individual responses to medications can vary. A healthcare provider will assess the potential benefits and risks for each patient and adjust the treatment plan as needed.

Frequently Asked Questions About Pantoprazole Sodium and Domperidone Capsules:

Certainly, here are some frequently asked questions (FAQs) about Pantoprazole Sodium and Domperidone Capsules:

  1. What are Pantoprazole Sodium and Domperidone Capsules, and what are they used for?

Pantoprazole Sodium and Domperidone Capsules are a combination medication that includes pantoprazole (a proton pump inhibitor) and domperidone (a prokinetic agent). They are primarily used to treat conditions related to excess stomach acid production, such as gastroesophageal reflux disease (GERD), peptic ulcers, and functional dyspepsia.

  1. How do Pantoprazole and Domperidone work together to manage gastrointestinal conditions?

Pantoprazole reduces stomach acid production, which helps alleviate symptoms of excess acidity like heartburn and acid regurgitation. Domperidone enhances gastrointestinal motility, aiding in the movement of food through the digestive tract and reducing symptoms like bloating and discomfort.

  1. Are there any specific precautions or considerations when taking these capsules?

It’s essential to follow your healthcare provider’s instructions and take the medication as prescribed. Do not adjust the dosage without consulting your healthcare provider. If you experience severe or persistent symptoms, contact your healthcare provider for guidance.

  1. Can Pantoprazole Sodium and Domperidone Capsules be used for long-term treatment?

Long-term use of these capsules may be necessary for certain conditions, but this should be determined by a healthcare provider. Regular monitoring and evaluation of the treatment plan are essential to ensure it remains effective and appropriate.

  1. Can I take these capsules with other medications or supplements?

Some medications or supplements may interact with Pantoprazole Sodium and Domperidone Capsules. It’s important to inform your healthcare provider about all the medications and supplements you are taking to prevent potential interactions.

  1. What should I do if I miss a dose of Pantoprazole Sodium and Domperidone Capsules?

If you miss a dose, take it as soon as you remember. However, if it’s close to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double up on doses to make up for a missed one.

  1. Are there any dietary or lifestyle recommendations while taking these capsules?

Your healthcare provider may provide dietary and lifestyle recommendations to complement your treatment. These may include dietary modifications, weight management, and avoiding triggers that exacerbate your gastrointestinal symptoms.

  1. Can I use Pantoprazole Sodium and Domperidone Capsules during pregnancy or while breastfeeding?

It’s crucial to inform your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding, as they will assess the benefits and risks of continuing or adjusting your medication. Individual considerations apply in these situations.

These FAQs provide general information about Pantoprazole Sodium and Domperidone Capsules, but individual recommendations and usage may vary. Always consult with a healthcare provider for personalized advice and guidance on the use of this medication, including potential benefits and risks.

As Pantoprazole Sodium and Domperidone Capsules Exporters; We can cater to export business queries from the following geographies. We are exporting our Pantoprazole Sodium and Domperidone Capsules product in the Following Countries-

Russia and CIS Countries: Azerbaijan, Armenia, Belarus, Georgia, Kazakhstan, Kyrgyzstan, Moldova, Russia, Tajikistan, Turkmenistan, Uzbekistan and Ukraine

GCC/ Middle East Countries: Saudi Arabia, Yemen, Oman, Bahrain, UAE, Lebanon, Jordan, and Iraq.

African Countries: Nigeria, Tanzania, Sudan, Zambia, Benin, Angola, Liberia

Southeast Asia: Cambodia, Indonesia, Laos, Malaysia, Myanmar, Philippines, Singapore, Thailand, Vietnam, Brunei Darussalam

Other Asian Countries: Nepal, Myanmar, Malaysia, Cambodia, Bhutan, Sri Lanka, Mauritius

Pantoprazole Sodium and Domperidone Capsules Regulatory Documents:

  • Certificate of Analysis (COA)
  • Method of Analysis (MOA)
  • Stability Data (Accelerated stability / Long-term stability / Zone 4b)
  • CTD Dossier / ACTD Dossiers / eCTD Dossiers
  • Certificate of Pharmaceuticals Product (COPP)
  • Free Sale Certificate (FSC)
Contact the most reliable manufacturer of Pantoprazole Sodium and Domperidone Capsules, Taj Pharmaceuticals Limited, to get bulk quantities at a reasonable price.

To Place Orders:

Direct line: +91 8448 444 095 / WhatsApp +91 74 0000 9975 / 74 0000 9976
E-Mail: info@tajpharma.com 
Toll free: 1-800-222-434 / Toll free: 1-800-222-825
General EPA BX: +91 22 2637 4592 / +91 22 2637 4593
Fax No: +91 22 2634 1274