GENERIC NAME OF THE MEDICINAL PRODUCT:

A. Dexamethasone Sodium Phosphate Injection USP 4 mg/ml (8mg/2ml, 20mg/5ml, 120mg/30ml)
B. Dexamethasone Sodium Phosphate Injection USP 10mg/ml (100mg/10ml)

QUALITATIVE AND QUANTITATIVE COMPOSITION:

A. Dexamethasone Sodium Phosphate Injection USP 4 mg/ml (8mg/2ml, 20mg/5ml, 120mg/30ml)
Each ml contains:
Dexamethasone Sodium Phosphate USP
Equivalent to Dexamethasone phosphate…………4mg
Water for Injection USP…………………………………. q.s.


B. Dexamethasone Sodium Phosphate Injection USP 10mg/ml (100mg/10ml)
Each ml contains:
Dexamethasone Sodium Phosphate USP
Equivalent to Dexamethasone phosphate…………10mg
Water for Injection USP…………………………………. q.s.

THERAPEUTIC INDICATIONS:

Dexamethasone is used to treat conditions such as arthritis, blood/hormone disorders, allergic reactions, skin diseases, eye problems, breathing problems, bowel disorders, cancer, and immune system disorders. It is also used as a test for an adrenal gland disorder (Cushing's syndrome).
The use of Dexamethasone Sodium Phosphate Injection USP in active tuberculosis should be restricted to those cases of fulminating or disseminated.
Dexamethasone Injection is used to treat severe allergic reactions.

PACKING:

1) 4mg/ml
a. 8mg/2ml
b. 20mg/5ml
c. 120mg/30ml
2) 10mg/ml
a. 100mg/10ml

DIRECTION OF USE:

For Intravenous/Intramuscular use only.
See insert for detailed dosage, directions for use and precautions.

CAUTION AND WARNING:

CAUTION: The injection should be discarded if any visible particle appears.
Discard any unused product immediately after use.
WARNING: Not to be sold by retail without the prescription of Registered Medical Practitioner.
Discard Unused portion.
Keep medicine out of reach of children.

STORAGE AND DOSAGE:

Storage: Store at 20° to 25°C.
Protected from light.
Dosage: As directed by the Physician.

Dexamethasone Sodium Phosphate Injection USP 4 mg/ml Technical Specification:

Product Name:Dexamethasone Sodium Phosphate Injection USP 4 mg/ml
Brand Name:Dexataj
Strength:4 mg/ml (8mg/2ml, 20mg/5ml, 120mg/30ml), 10mg/ml (100mg/10ml)
Dosage Form:Liquid Injection (Ampoule/Vial)
Packing:1 mL, 5 mL, 10 mL, 30 mL
Route of Administration:For Intravenous/Intramuscular use only
Pack Insert/Leaflet:PIL (Patient Information Leaflet), SmPC (Summary Product Characteristics)
Regulatory Documents:COA, MOA, COPP, FSC, Stability Studies, GMP, CTD Dossier
Therapeutic use:Corticosteroids
Indication: Dexamethasone is used to treat conditions such as arthritis, blood/hormone disorders, allergic reactions, skin diseases, eye problems, breathing problems, bowel disorders, cancer, and immune system disorders. It is also used as a test for an adrenal gland disorder (Cushing’s syndrome).
Storage:Store at 20° to 25°C. Protected from light.

GENERIC NAME OF THE MEDICINAL PRODUCT:

  • Dexamethasone Sodium Phosphate Injection USP 4 mg/ml (8mg/2ml, 20mg/5ml, 120mg/30ml)

QUALITATIVE AND QUANTITATIVE COMPOSITION:

  • Dexamethasone Sodium Phosphate Injection USP 4 mg/ml (8mg/2ml, 20mg/5ml, 120mg/30ml)
    Each ml contains:
    Dexamethasone Sodium Phosphate USP
    Equivalent to Dexamethasone phosphate…………4mg
    Water for Injection USP…………………………………. q.s.

THERAPEUTIC INDICATION:

Dexamethasone is used to treat conditions such as arthritis, blood/hormone disorders, allergic reactions, skin diseases, eye problems, breathing problems, bowel disorders, cancer, and immune system disorders. It is also used as a test for an adrenal gland disorder (Cushing’s syndrome).
The use of Dexamethasone Sodium Phosphate Injection USP in active tuberculosis should be restricted to those cases of fulminating or disseminated.=
Dexamethasone Injection is used to treat severe allergic reactions.

PACKING:

  • 4mg/ml
  1. 8mg/2ml
  2. 20mg/5ml
  3. 120mg/30ml
  • 10mg/ml
  1. 100mg/10ml

DIRECTION OF USE:

For Intravenous/Intramuscular use only.
See insert for detailed dosage, directions for use and precautions.

CAUTION & WARNING:

CAUTION: The injection should be discarded if any visible particle appears.
Discard any unused product immediately after use.
WARNING: Not to be sold by retail without the prescription of Registered Medical Practitioner.
Discard Unused portion.
Keep medicine out of reach of children.

STORAGE & DOSAGE:

Storage: Store at 20° to 25°C. Protected from light.
Dosage:  As directed by the Physician.

Why Taj Pharmaceuticals?

Taj Pharmaceuticals is a reputable pharmaceutical company known for its commitment to delivering high-quality medications, including Dexamethasone Sodium Phosphate Injection. This commitment is rooted in a dedication to upholding the highest standards of pharmaceutical manufacturing and quality assurance, ensuring that patients receive safe and effective medications. Dexamethasone Sodium Phosphate Injection is a critical medication with various medical applications, and Taj Pharmaceuticals’ focus on quality and innovation makes it a trusted provider in the healthcare industry. The company’s adherence to stringent international quality standards underscores its commitment to patient safety and well-being. Reliability is a hallmark of Taj Pharmaceuticals’ services. Healthcare providers and patients can trust in the consistent availability of Dexamethasone Sodium Phosphate Injection, ensuring that critical medical treatments are readily accessible when needed. This reliability is particularly crucial in emergency and acute care situations. Moreover, Taj Pharmaceuticals places a strong emphasis on affordability, making high-quality medications accessible to a broader population. This commitment ensures that financial constraints do not hinder patients from receiving the best possible care. The trust and reputation that Taj Pharmaceuticals has earned from healthcare professionals and patients alike solidify its position as a preferred pharmaceutical provider. The company’s dedication to quality, innovation, affordability, and patient well-being makes it a reliable choice for individuals and healthcare providers seeking dependable and effective treatment options. Patients should always consult with a healthcare professional for personalized guidance on the appropriate use of Dexamethasone Sodium Phosphate Injection and other medications from Taj Pharmaceuticals.

What is Dexamethasone Sodium Phosphate Injection and its uses?

Dexamethasone Sodium Phosphate Injection is a medication that contains the active ingredient dexamethasone, a potent synthetic corticosteroid. This injection is used for various medical purposes due to its anti-inflammatory and immunosuppressive properties. Here are some of its primary uses:

  • Inflammatory Conditions: Dexamethasone Sodium Phosphate Injection is commonly prescribed to treat a wide range of inflammatory conditions, including:
    Allergic reactions
    Skin conditions like eczema and psoriasis
    Respiratory conditions like asthma and chronic obstructive pulmonary disease (COPD)
    Rheumatoid arthritis and other autoimmune disorders
    Inflammatory bowel diseases like Crohn’s disease and ulcerative colitis
  • Allergic Reactions: It is often used to manage severe allergic reactions, such as anaphylaxis, to reduce inflammation and prevent further complications.
  • Cancer Treatment: Dexamethasone can be part of cancer treatment regimens to manage side effects of chemotherapy, including nausea, vomiting, and allergic reactions.
  • Cerebral Edema: In cases of brain injuries or tumors causing cerebral edema (brain swelling), dexamethasone may be administered to reduce swelling and relieve pressure within the skull.
  • Autoimmune Diseases: Dexamethasone is used in autoimmune diseases like lupus to suppress the immune system’s abnormal response, thereby reducing inflammation and alleviating symptoms.
  • Endocrine Disorders: It may be prescribed for certain endocrine disorders, such as adrenal insufficiency (Addison’s disease), to replace inadequate natural corticosteroid production.
  • Postoperative Swelling: After certain surgeries, Dexamethasone Sodium Phosphate Injection can help reduce postoperative swelling and inflammation.
  • Respiratory Distress Syndrome (in preterm infants): In preterm infants at risk of respiratory distress syndrome (RDS), dexamethasone may be given to accelerate lung development and reduce the risk of respiratory complications.

It’s important to note that Dexamethasone Sodium Phosphate Injection is a potent medication with significant anti-inflammatory and immunosuppressive effects. It is typically administered by healthcare professionals in hospital settings or under the supervision of a healthcare provider. The dosage and duration of treatment vary depending on the specific medical condition being treated, and treatment plans are tailored to the individual patient’s needs. Patients should follow their healthcare provider’s instructions closely when receiving this injection.

How does Dexamethasone Sodium Phosphate Injection work?

Dexamethasone Sodium Phosphate Injection contains dexamethasone, a synthetic corticosteroid medication. It exerts its therapeutic effects through several mechanisms, primarily by influencing the body’s immune response and inflammatory processes. Here’s how Dexamethasone Sodium Phosphate Injection works:

  • Anti-Inflammatory Action: Dexamethasone is a potent anti-inflammatory agent. It works by inhibiting the release of various inflammatory mediators, such as prostaglandins and leukotrienes, from immune cells like macrophages and white blood cells. By reducing inflammation, it alleviates the associated symptoms, such as pain, redness, swelling, and heat. This anti-inflammatory action is beneficial in treating conditions like arthritis, allergic reactions, and inflammatory skin disorders.
  • Immunosuppression: Dexamethasone suppresses the immune system’s response, particularly the activity of white blood cells called lymphocytes. This immunosuppressive effect is valuable in autoimmune diseases like lupus or rheumatoid arthritis, where the immune system mistakenly attacks the body’s own tissues. By dampening the immune response, it reduces tissue damage and inflammation.
  • Stabilization of Cell Membranes: Dexamethasone stabilizes cell membranes and prevents the release of enzymes responsible for tissue breakdown. This can reduce tissue damage caused by inflammation and minimize swelling.
  • Anti-Allergic Effects: In allergic reactions, the body’s immune system overreacts to allergens, leading to inflammation and symptoms like itching and swelling. Dexamethasone helps suppress this exaggerated immune response and provides relief from allergy symptoms.
  • Management of Cerebral Edema: In cases of cerebral edema (brain swelling), often resulting from brain injuries or tumors, dexamethasone can reduce the swelling and pressure within the skull. It works by decreasing inflammation and stabilizing cell membranes in the brain.
  • Acceleration of Lung Development (in preterm infants): Dexamethasone is sometimes used in preterm infants to accelerate lung development. It stimulates the production of surfactant, a substance that prevents the collapse of tiny air sacs (alveoli) in the lungs, reducing the risk of respiratory distress syndrome (RDS).

Dexamethasone Sodium Phosphate Injection is a versatile medication used to manage a wide range of medical conditions due to its anti-inflammatory and immunosuppressive properties. The specific mechanism of action can vary depending on the condition being treated, but the overall goal is to reduce inflammation and modulate the immune response to alleviate symptoms and improve patient outcomes. It is essential to use this medication under the supervision of a healthcare provider, as dosage and duration of treatment should be carefully tailored to the individual patient’s needs.

Benefits of Dexamethasone Sodium Phosphate Injection:

  • Anti-Inflammatory Action: Dexamethasone is highly effective in reducing inflammation, making it a valuable tool in treating a wide range of inflammatory conditions such as arthritis, allergic reactions, and inflammatory skin disorders.
  • Immunosuppression: Dexamethasone’s immunosuppressive properties are beneficial in autoimmune diseases like lupus and rheumatoid arthritis, where the immune system attacks the body’s own tissues. By suppressing the immune response, it helps reduce tissue damage and inflammation.
  • Management of Allergic Reactions: Dexamethasone provides rapid relief from severe allergic reactions, including anaphylaxis, by suppressing the excessive immune response responsible for allergic symptoms.
  • Cerebral Edema Management: It is crucial in reducing brain swelling (cerebral edema) following brain injuries or tumors. By minimizing inflammation in the brain, it can relieve intracranial pressure and prevent neurological complications.
  • Postoperative Swelling Reduction: After certain surgeries, Dexamethasone Sodium Phosphate Injection can help reduce postoperative swelling and inflammation, promoting quicker recovery.
  • Respiratory Distress Syndrome Prevention (in preterm infants): Administered to preterm infants at risk of respiratory distress syndrome (RDS), it accelerates lung development by stimulating surfactant production, reducing the likelihood of breathing difficulties.

Common Side Effects of Dexamethasone Sodium Phosphate Injection:

  • Gastrointestinal Issues: Nausea, vomiting, and gastrointestinal discomfort are common side effects. Taking the medication with food can help alleviate these symptoms.
  • Increased Appetite: Some individuals may experience increased hunger and weight gain while taking dexamethasone.
  • Mood Changes: Dexamethasone can affect mood, leading to mood swings, irritability, or even depression in some cases.
  • Insomnia: Difficulty falling asleep or staying asleep (insomnia) can occur during treatment with dexamethasone.
  • Fluid Retention: Fluid retention may lead to swelling in the extremities and increased blood pressure.
  • Increased Risk of Infections: Dexamethasone suppresses the immune system, increasing susceptibility to infections. Patients should take precautions to avoid exposure to contagious illnesses.
  • Osteoporosis: Long-term use of dexamethasone can lead to bone loss and an increased risk of fractures.
  • Glucose Intolerance: Dexamethasone can cause elevated blood glucose levels, which may be problematic for individuals with diabetes or those at risk of developing diabetes.
  • Cataracts and Glaucoma: Prolonged use of dexamethasone may increase the risk of cataracts and glaucoma.
  • Skin Changes: Skin thinning, easy bruising, and delayed wound healing are possible side effects.

It’s important to note that the benefits of Dexamethasone Sodium Phosphate Injection often outweigh the potential side effects, especially when used to manage severe inflammatory conditions or life-threatening allergic reactions. Healthcare providers carefully consider the risks and benefits when prescribing this medication, and treatment plans are tailored to individual patient needs. Patients should communicate openly with their healthcare team about any side effects or concerns during treatment.

Frequently Asked Questions About Dexamethasone Sodium Phosphate Injection:

Certainly, here are some frequently asked questions about Dexamethasone Sodium Phosphate Injection:

  1. What is Dexamethasone Sodium Phosphate Injection used for?

Dexamethasone Sodium Phosphate Injection is used to treat various medical conditions, including inflammatory disorders, allergic reactions, autoimmune diseases, and to manage cerebral edema.

  1. How is Dexamethasone Sodium Phosphate Injection administered?

It is typically administered as an intravenous (IV) injection or as an intramuscular (IM) injection. The dosage and method of administration depend on the specific medical condition and the healthcare provider’s recommendations.

  1. How quickly does Dexamethasone Sodium Phosphate Injection work?

The onset of action can vary, but relief from symptoms such as inflammation and allergic reactions is often observed within hours to a few days after administration.

  1. Are there any dietary restrictions while taking Dexamethasone Sodium Phosphate Injection?

There are no specific dietary restrictions, but it’s advisable to maintain a balanced diet and monitor blood glucose levels, especially in individuals with diabetes, as dexamethasone can affect blood sugar levels.

  1. Can Dexamethasone Sodium Phosphate Injection be used during pregnancy or breastfeeding?

It should be used during pregnancy only if the potential benefits outweigh the risks. It may pass into breast milk, so its use while breastfeeding should be discussed with a healthcare provider.

  1. Can I stop taking Dexamethasone Sodium Phosphate Injection abruptly?

Abruptly stopping dexamethasone after prolonged use can lead to adrenal insufficiency. It is crucial to follow the healthcare provider’s instructions for tapering off the medication gradually.

  1. Are there any drug interactions with Dexamethasone Sodium Phosphate Injection?

Dexamethasone can interact with various medications, so it’s essential to inform your healthcare provider about all the medications and supplements you are taking to prevent potential interactions.

  1. What should I do if I miss a dose of Dexamethasone Sodium Phosphate Injection?

If you miss a dose, contact your healthcare provider for guidance. It may be necessary to adjust the dosing schedule, but do not double the dose to make up for a missed one.

  1. Can Dexamethasone Sodium Phosphate Injection be used long-term?

Long-term use of dexamethasone should be carefully monitored due to the risk of side effects, such as osteoporosis, weight gain, and immune suppression. Healthcare providers aim to find the lowest effective dose and limit the duration of treatment.

  1. What should I do if I experience side effects while taking Dexamethasone Sodium Phosphate Injection?

Contact your healthcare provider immediately if you experience severe or concerning side effects. They can assess the situation and adjust your treatment plan if necessary.

Patients should consult their healthcare providers for personalized guidance and answers to specific questions regarding the use of Dexamethasone Sodium Phosphate Injection for their particular medical condition.

As Dexamethasone Sodium Phosphate Injection Exporters; We can cater to export business queries from the following geographies. We are exporting our Dexamethasone Sodium Phosphate Injection product in the Following Countries-

Russia and CIS Countries: Azerbaijan, Armenia, Belarus, Georgia, Kazakhstan, Kyrgyzstan, Moldova, Russia, Tajikistan, Turkmenistan, Uzbekistan and Ukraine

GCC/ Middle East Countries: Saudi Arabia, Yemen, Oman, Bahrain, UAE, Lebanon, Jordan, and Iraq.

African Countries: Nigeria, Tanzania, Sudan, Zambia, Benin, Angola, Liberia

Southeast Asia: Cambodia, Indonesia, Laos, Malaysia, Myanmar, Philippines, Singapore, Thailand, Vietnam, Brunei Darussalam

Other Asian Countries: Nepal, Myanmar, Malaysia, Cambodia, Bhutan, Sri Lanka, Mauritius

Dexamethasone Sodium Phosphate Injection Regulatory Documents:

  • Certificate of Analysis (COA)
  • Method of Analysis (MOA)
  • Stability Data (Accelerated stability / Long-term stability / Zone 4b)
  • CTD Dossier / ACTD Dossiers / eCTD Dossiers
  • Certificate of Pharmaceuticals Product (COPP)
  • Free Sale Certificate (FSC)
Contact the most reliable manufacturer of Dexamethasone Sodium Phosphate Injection, Taj Pharmaceuticals Limited, to get bulk quantities at a reasonable price.

To Place Orders:

Direct line: +91 8448 444 095 / WhatsApp +91 74 0000 9975 / 74 0000 9976
E-Mail: info@tajpharma.com 
Toll free: 1-800-222-434 / Toll free: 1-800-222-825
General EPA BX: +91 22 2637 4592 / +91 22 2637 4593
Fax No: +91 22 2634 1274