GENERIC NAME OF THE MEDICINAL PRODUCT:

A. Chlorpromazine Hydrochloride Injection USP 25mg/ml
B. Chlorpromazine Hydrochloride Injection USP 50mg/2ml

QUALITATIVE AND QUANTITATIVE COMPOSITION:

A. Chlorpromazine Hydrochloride Injection USP 25mg/ml
Each ml contains:
Chlorpromazine Hydrochloride USP…………………25mg
Water for Injection USP…………………………………. q.s.

B. Chlorpromazine Hydrochloride Injection USP 50mg/2ml
Each ml contains:
Chlorpromazine Hydrochloride USP…………………25mg
Water for Injection USP…………………………………. q.s.


THERAPEUTIC INDICATIONS:

This medication is used to treat certain mental/mood disorders (such as schizophrenia, psychotic disorders, the manic phase of bipolar disorder, severe behavioural problems in children).
Chlorpromazine HCL 25mg/ml; for IV injection after dilution or IM injection; contains sulfites; multi dose vial contains benzyl alcohol.

PACKING:

1) 25mg/ml
2) 50mg/2ml

DIRECTION OF USE:

For deep intramuscular use.
See insert for detailed dosage, directions for use and precautions.

CAUTION AND WARNING:

CAUTION: The injection should be discard if any visible particle appears.
Discard any unused product immediately after use.
WARNING: Not to be sold by retail without the prescription of Registered Medical Practitioner.
Discard Unused portion.
Keep medicine out of reach of children.

STORAGE AND DOSAGE:

Storage: Store protected from light.
Dosage: As directed by the Physician.

Chlorpromazine Hydrochloride Injection USP 50mg/2ml Technical Specification:

Product Name:Chlorpromazine Hydrochloride Injection USP 50mg/2ml
Brand Name:Generic
Strength:25mg/ml (50mg/2ml)
Dosage Form:Liquid Injection
Packing:Single Dose Ampoule
Route of Administration:For deep intramuscular use
Pack Insert/Leaflet:PIL (Patient Information Leaflet), SmPC (Summary Product Characteristics)
Regulatory Documents:COA, MOA, COPP, FSC, Stability Studies, GMP, CTD Dossier
Therapeutic use:Antipsychotics
Indication: This medication is used to treat certain mental/mood disorders (such as schizophrenia, psychotic disorders, the manic phase of bipolar disorder, severe behavioural problems in children).
Storage:Store protected from light.

GENERIC NAME OF THE MEDICINAL PRODUCT:

  • Chlorpromazine Hydrochloride Injection USP 50mg/2ml

QUALITATIVE AND QUANTITATIVE COMPOSITION:

  • Chlorpromazine Hydrochloride Injection USP 50mg/2ml
    Each ml contains:
    Chlorpromazine Hydrochloride USP…………………25mg
    Water for Injection USP…………………………………. q.s.

THERAPEUTIC INDICATION:

This medication is used to treat certain mental/mood disorders (such as schizophrenia, psychotic disorders, the manic phase of bipolar disorder, severe behavioural problems in children).

Chlorpromazine HCL 25mg/ml; for IV injection after dilution or IM injection; contains sulfites; multi dose vial contains benzyl alcohol.

PACKING:

1) 25mg/ml
2) 50mg/2ml

DIRECTION OF USE:

For deep intramuscular use.

See insert for detailed dosage, directions for use and precautions.

CAUTION & WARNING:

CAUTION: The injection should be discard if any visible particle appears.

Discard any unused product immediately after use.

WARNING: Not to be sold by retail without the prescription of Registered Medical Practitioner.

Discard Unused portion.

Keep medicine out of reach of children.

STORAGE & DOSAGE:

Storage: Store protected from light.

Dosage:  As directed by the Physician.

Why Taj Pharmaceuticals?

Taj Pharma is your trusted source for Chlorpromazine Hydrochloride Injection USP. With a legacy of pharmaceutical excellence, stringent quality control, and unwavering commitment to patient care, Taj Pharma offers reliable solutions for mental health and behavioral disorders. Explore the benefits of choosing Taj Pharma for your Chlorpromazine Hydrochloride Injection needs and experience the difference in healthcare excellence.

Choose Taj Pharma for Chlorpromazine Hydrochloride Injection USP, and access pharmaceutical expertise that prioritizes your well-being. Taj Pharma boasts a long-standing history of producing high-quality medications, particularly in the field of mental health and behavioral disorders. Our Chlorpromazine Hydrochloride Injection USP exemplifies our commitment to stringent quality control, ensuring that patients receive safe and effective treatments. With a focus on delivering innovative solutions and enhancing patient care, Taj Pharma stands as a trusted name in healthcare. When you choose Taj Pharma, you’re choosing pharmaceutical excellence that makes a real difference in the lives of those who depend on our medications. Taj Pharma’s dedication to quality, patient care, and innovation makes it a preferred choice for Chlorpromazine Hydrochloride Injection USP and various other pharmaceutical products.

What is Chlorpromazine Hydrochloride Injection USP and its use?

Chlorpromazine Hydrochloride Injection USP contains the active ingredient chlorpromazine hydrochloride, which belongs to a class of medications known as typical antipsychotics. It is administered in injectable form for specific medical purposes. Here’s a brief overview:

  • Active Ingredient: Chlorpromazine hydrochloride is the active compound in this medication. It exerts its effects by blocking dopamine receptors in the brain.

Uses of Chlorpromazine Hydrochloride Injection USP:

  • Psychosis Management: Chlorpromazine is primarily used for the treatment of various mental health conditions characterized by symptoms like delusions, hallucinations, and disorganized thinking. These may occur in conditions like schizophrenia or other psychotic disorders.
  • Agitation and Aggression: It may be administered in acute situations to manage severe agitation, aggression, or violent behavior in individuals with mental health disorders.
  • Nausea and Vomiting: Chlorpromazine can also be used to alleviate severe nausea and vomiting, particularly when other antiemetic medications have not provided sufficient relief.
  • Intractable Hiccups: In cases of persistent and severe hiccups that do not respond to other treatments, chlorpromazine may be used to provide relief.
  • Acute Anxiety and Excitement: It may be employed in emergency situations to calm individuals experiencing acute anxiety or extreme states of excitement.

Chlorpromazine Hydrochloride Injection USP is administered under the supervision of a healthcare professional in a clinical setting. The dosage and duration of treatment will be determined based on the specific medical condition being addressed. As with any medication, it’s crucial to discuss potential benefits, risks, and any potential interactions with other medications or conditions with a healthcare provider. Additionally, patients receiving chlorpromazine should be closely monitored for any signs of adverse effects or reactions.

How does Chlorpromazine Hydrochloride Injection USP work?

Chlorpromazine Hydrochloride Injection USP works by affecting the levels of certain neurotransmitters, or chemical messengers, in the brain. It primarily exerts its effects by blocking the action of dopamine, a neurotransmitter that plays a significant role in regulating mood, behavior, and perception. Here’s how Chlorpromazine works:

  • Dopamine Receptor Blockade: Chlorpromazine is classified as a typical anti-psychotic medication. It acts as an antagonist to dopamine receptors, particularly the D2 receptors in the brain. By binding to these receptors, it inhibits the activity of dopamine, reducing its effects.
  • Correction of Dopamine Imbalance: In conditions like schizophrenia and other psychotic disorders, there is often an imbalance of dopamine activity in the brain. Excess dopamine activity can lead to symptoms such as hallucinations, delusions, and disorganized thinking. Chlorpromazine helps correct this imbalance by reducing the excessive stimulation of dopamine receptors.
  • Sedative and Calming Effects: Chlorpromazine also has sedative properties, which can help calm individuals who may be experiencing extreme agitation, aggression, or acute anxiety. It can promote a sense of relaxation and tranquility.
  • Antiemetic Effects: In cases of severe nausea and vomiting, Chlorpromazine may be used to block the signals in the brain that trigger nausea and vomiting. This antiemetic effect can be particularly useful in managing chemotherapy-induced nausea or postoperative vomiting.
  • Treatment of Intractable Hiccups: The mechanism by which Chlorpromazine treats intractable hiccups is not entirely understood, but it is believed to involve its central nervous system depressant effects, which can help relax the diaphragm and reduce the frequency of hiccups.

Benefits of Chlorpromazine Hydrochloride Injection USP:

  • Psychosis Management: Chlorpromazine is effective in managing symptoms of psychosis, such as delusions and hallucinations, making it a valuable tool in the treatment of conditions like schizophrenia.
  • Agitation and Aggression: It can help calm individuals experiencing severe agitation, aggression, or violent behavior, especially in emergency situations.
  • Nausea and Vomiting Relief: Chlorpromazine is useful in alleviating severe nausea and vomiting, particularly when other antiemetic medications have not provided sufficient relief.
  • Intractable Hiccups: In cases of persistent and severe hiccups that do not respond to other treatments, Chlorpromazine may provide relief.
  • Acute Anxiety Management: In acute situations of extreme anxiety or excitement, Chlorpromazine can help induce a sense of relaxation and tranquility.

Side Effects of Chlorpromazine Hydrochloride Injection USP:

  • Sedation: One of the common side effects of Chlorpromazine is sedation or drowsiness. This can impair alertness and coordination, making activities like driving or operating heavy machinery potentially dangerous.
  • Extrapyramidal Symptoms (EPS): These can include muscle stiffness, tremors, and restlessness, which are side effects related to the medication’s effect on dopamine receptors. In some cases, tardive dyskinesia, a movement disorder, may develop with long-term use.
  • Orthostatic Hypotension: Chlorpromazine can cause a drop in blood pressure when changing positions, leading to dizziness or fainting upon standing up quickly.
  • Weight Gain: Some individuals may experience weight gain while taking Chlorpromazine, which can be a concern for long-term users.
  • Anticholinergic Effects: These can include dry mouth, blurred vision, constipation, and urinary retention.
  • Hypersensitivity Reactions: Allergic reactions, though rare, may occur and can include skin rashes, itching, and swelling.
  • Endocrine Effects: Chlorpromazine may lead to hormonal changes, including increased levels of the hormone prolactin, which can result in menstrual irregularities and breast enlargement in both men and women.
  • Neuroleptic Malignant Syndrome (NMS): This is a rare but potentially life-threatening condition associated with antipsychotic medications like Chlorpromazine. Symptoms may include fever, muscle rigidity, altered mental status, and autonomic dysfunction.

Frequently asked questions (FAQs) about Chlorpromazine Hydrochloride Injection USP:

  1. What is Chlorpromazine Hydrochloride Injection USP used for?

Chlorpromazine Hydrochloride Injection USP is primarily used to manage symptoms of psychosis, including delusions and hallucinations, and it can also be used to alleviate severe nausea, vomiting, agitation, and extreme anxiety.

  1. How does Chlorpromazine work to treat psychosis?

Chlorpromazine works by blocking dopamine receptors in the brain, helping to correct imbalances in dopamine activity that are associated with symptoms of psychosis.

  1. Is Chlorpromazine safe for longterm use?

Longterm use of Chlorpromazine may be considered in some cases, but it should be closely monitored by a healthcare provider due to the potential for side effects and the development of movement disorders like tardive dyskinesia.

  1. Can Chlorpromazine cause drowsiness?

Yes, sedation and drowsiness are common side effects of Chlorpromazine. Individuals taking this medication should avoid activities that require mental alertness, such as driving, until they know how the medication affects them.

  1. What should I do if I miss a dose of Chlorpromazine Injection?

If you miss a dose, contact your healthcare provider for guidance. It may be necessary to adjust the dosing schedule.

  1. Can Chlorpromazine Injection be used in children or adolescents?

Chlorpromazine may be prescribed to pediatric patients in specific cases, but the dosage and duration of treatment should be determined by a healthcare provider based on the child’s age and condition.

  1. Are there any potential drug interactions with Chlorpromazine?

Yes, Chlorpromazine may interact with other medications. It’s important to inform your healthcare provider about all the drugs and supplements you are taking to avoid potential interactions.

  1. Can I suddenly stop taking Chlorpromazine?

No, you should not stop taking Chlorpromazine abruptly without consulting your healthcare provider. Doing so can lead to withdrawal symptoms and a worsening of the underlying condition. The dosge should be tapered down under medical supervision.

  1. Can Chlorpromazine cause weight gain?

Yes, weight gain is a potential side effect of Chlorpromazine. It’s important to discuss any concerns about weight changes with your healthcare provider.

  1. What are the signs of neuroleptic malignant syndrome (NMS)?

NMS is a rare but serious condition associated with antipsychotic medications like Chlorpromazine. Symptoms may include high fever, muscle stiffness, altered mental status, and autonomic dysfunction. If you experience these symptoms, seek immediate medical attention.

As Chlorpromazine Hydrochloride Injection USP Exporters; We can cater to export business queries from the following geographies. We are exporting our Chlorpromazine Hydrochloride Injection USP product in the Following Countries-

Russia and CIS Countries: Azerbaijan, Armenia, Belarus, Georgia, Kazakhstan, Kyrgyzstan, Moldova, Russia, Tajikistan, Turkmenistan, Uzbekistan and Ukraine

GCC/ Middle East Countries: Saudi Arabia, Yemen, Oman, Bahrain, UAE, Lebanon, Jordan, and Iraq.

African Countries: Nigeria, Tanzania, Sudan, Zambia, Benin, Angola, Liberia

Southeast Asia: Cambodia, Indonesia, Laos, Malaysia, Myanmar, Philippines, Singapore, Thailand, Vietnam, Brunei Darussalam

Other Asian Countries: Nepal, Myanmar, Malaysia, Cambodia, Bhutan, Sri Lanka, Mauritius

Chlorpromazine Hydrochloride Injection USP Regulatory Documents:

  • Certificate of Analysis (COA)
  • Method of Analysis (MOA)
  • Stability Data (Accelerated stability / Long-term stability / Zone 4b)
  • CTD Dossier / ACTD Dossiers / eCTD Dossiers
  • Certificate of Pharmaceuticals Product (COPP)
  • Free Sale Certificate (FSC)
Contact the most reliable manufacturer of Chlorpromazine Hydrochloride Injection USP, Taj Pharmaceuticals Limited, to get bulk quantities at a reasonable price.

To Place Orders:

Direct line: +91 8448 444 095 / WhatsApp +91 74 0000 9975 / 74 0000 9976
E-Mail: info@tajpharma.com 
Toll free: 1-800-222-434 / Toll free: 1-800-222-825
General EPA BX: +91 22 2637 4592 / +91 22 2637 4593
Fax No: +91 22 2634 1274