GENERIC NAME OF THE MEDICINAL PRODUCT:

(A) Caspofungin Acetate for Injection 50mg
(B) Caspofungin Acetate for Injection 70mg

QUALITATIVE AND QUANTITATIVE COMPOSITION:

A) Caspofungin Acetate for Injection 50mg
a) Each vial contains:
Caspofungin Acetate
equivalent to Caspofungin………………50 mg
Excipients…………………………………………q.s.
b) Ampoule contains:
Water for Injection USP …………………10 ml

B) Caspofungin Acetate for Injection 70mg
a) Each vial contains:
Caspofungin Acetate
equivalent to Caspofungin………………70 mg
Excipients……………………………………………q.s.
b) Ampoule contains:
Water for Injection USP …………………10 ml


THERAPEUTIC INDICATIONS:

Caspofungin injection is used to treat serious fungal infections, including candidemia (fungal infection in the blood), esophageal candidiasis (fungal infection of the esophagus), other candida infections, and aspergillosis (fungal infection in the lungs).

DIRECTION OF USE:

Each vial when reconstituted to 10ml contains 5mg/ml & 7mg/ml. Caspofungin as active ingredient.
Intravenous use after reconstitution and dilution.
For indication, dosage and administration, see enclose leaflet.

CAUTION & WARNING:

CAUTION: Do not use the Injection if the content visible particulate matter after reconstitution.
Do not reconstitute with Dextrose (a-D-Glucose).
Warning: To be sold by the retail on the prescription of a registered medical practitioner only.

STORAGE & DOSAGE:

Storage: Store at 2°C-8°C.
KEEP MEDICINE OUT OF REACH OF CHILDREN.
FLIP-OFF SEAL IS PROVIDED FOR TAMPER EVIDENCE
For indications, dosage and administration, see enclosed leaflet.
Dosage: As directed by Physician.

Caspofungin Acetate for Injection 70mg Technical Specification:

Product Name:Caspofungin Acetate for Injection 70mg
Brand Name:Wofuntaj
Strength:50mg, 70mg
Dosage Form:Lyophilized
Dry Powder for Solution for Injection/Infusion
Packing:1 Vial + WFI in a Tray
Route of Administration:For I.V. use only
Pack Insert/Leaflet:PIL (Patient Information Leaflet), SmPC (Summary Product Characteristics)
Regulatory Documents:COA, MOA, COPP, FSC, Stability Studies, GMP, CTD Dossier
Therapeutic use:Anti-fungal
Indication: Caspofungin injection is used to treat serious fungal infections, including candidemia, esophageal candidiasis, other candida infections, and aspergillosis.
Storage:Store at 2°C to 8°C.

GENERIC NAME OF MEDICINAL PRODUCT:

  • Caspofungin Acetate for Injection 70mg

QUALITATIVE AND QUANTITATIVE COMPOSITION:

  • Caspofungin Acetate for Injection 70mg
    Each vial contains:
    Caspofungin Acetate
    equivalent to Caspofungin………………70 mg
    Excipients…………………………………………q.s.
    Ampoule contains:
    Water for Injection USP …………………10 ml

THERAPEUTIC INDICATION:

Caspofungin injection is used to treat serious fungal infections, including candidemia (fungal infection in the blood), esophageal candidiasis (fungal infection of the esophagus), other candida infections, and aspergillosis (fungal infection in the lungs).

DIRECTION OF USE:

Each vial when reconstituted to 10ml contains 5mg/ml & 7mg/ml. Caspofungin as active ingredient.
Intravenous use after reconstitution and dilution.
For indication, dosage and administration, see enclose leaflet.

CAUTION & Warning:

CAUTION: Do not use the Injection if the content visible particulate matter after reconstitution.
Do not reconstitute with Dextrose (a-D-Glucose)
Warning: To be sold by the retail on the prescription of a registered medical practitioner only.

STORAGE & DOSAGE:

Storage: Store at 2°C-8°C.
KEEP MEDICINE OUT OF REACH OF CHILDREN.?
FLIP-OFF SEAL IS PROVIDED FOR TAMPER EVIDENCE
For indications, dosage and administration, see enclosed leaflet.
Dosage: As directed by Physician.

Why Taj Pharmaceuticals?

Taj Pharmaceuticals stands as a pioneer in providing Caspofungin Acetate for Injection, a vital medication essential in combatting invasive fungal infections. Our unwavering dedication to quality, safety, and innovation ensures that every vial of Caspofungin Acetate meets the highest global standards. For decades, Taj Pharmaceuticals has been synonymous with trust in the pharmaceutical industry, delivering life-saving medications to healthcare professionals and patients worldwide. Our commitment to accessibility ensures that individuals in need have access to top-quality pharmaceuticals, including Caspofungin Acetate. Our state-of-the-art manufacturing facilities adhere to the most rigorous quality control protocols, guaranteeing the purity and efficacy of every dose. Whether in critical care or routine antifungal therapy, healthcare providers trust Taj Pharmaceuticals for reliable and effective medications. Choose Taj Pharmaceuticals for Caspofungin Acetate for Injection and experience pharmaceutical excellence that prioritizes your health and well-being. We are here to support healthcare providers and patients, providing the quality and reliability you deserve in the fight against invasive fungal diseases.

What is Caspofungin Acetate for Injection and its uses:

Caspofungin Acetate for Injection is a medication used in the treatment of fungal infections. It belongs to a class of antifungal drugs known as echinocandins. Here’s an overview of Caspofungin Acetate for Injection and its primary uses:

  • Composition:
    Caspofungin acetate is the active ingredient in Caspofungin Acetate for Injection.
  • Uses:
    Invasive Aspergillosis: Caspofungin Acetate for Injection is primarily used to treat invasive aspergillosis, a serious fungal infection caused by the Aspergillus species. Invasive aspergillosis can affect various organs and systems in the body and is often seen in individuals with compromised immune systems.
    Invasive Candidiasis: It is also indicated for the treatment of invasive candidiasis, a fungal infection caused by Candida species. Invasive candidiasis can affect internal organs and is common in critically ill patients, transplant recipients, or those receiving chemotherapy.
    Esophageal Candidiasis: Caspofungin may also be used to treat esophageal candidiasis, a fungal infection of the esophagus.
  • Mechanism of Action:
    Caspofungin Acetate for Injection works by inhibiting the synthesis of a key component of the fungal cell wall called beta1,3Dglucan. This disruption weakens the fungal cell wall, leading to the rupture and death of the fungal cells. Importantly, this mechanism of action is specific to fungi and does not affect human cells, making it a targeted and low-toxicity antifungal therapy.
  • Administration:
    Caspofungin Acetate for Injection is administered as an intravenous infusion in a hospital or clinical setting. The dosage and duration of treatment depend on the specific fungal infection and the patient’s response.
  • Clinical Considerations:
    Caspofungin is typically used in patients with confirmed or suspected fungal infections, especially when other antifungal medications may not be suitable due to resistance or safety concerns. The decision to use Caspofungin is made by healthcare providers based on the patient’s clinical condition and the results of diagnostic tests.
  • Prevention:
    While it is primarily used for the treatment of fungal infections, in some cases, Caspofungin may be used to prevent invasive fungal infections in high-risk patients undergoing certain medical procedures or treatments.

Caspofungin Acetate for Injection is an essential tool in the treatment of serious fungal infections, particularly in patients with compromised immune systems or those with severe underlying medical conditions where fungal infections can be life-threatening. The choice of antifungal medication depends on the type of infection, patient-specific factors, and potential risks and benefits.

How do Caspofungin Acetate for Injection Work?

Caspofungin Acetate for Injection works by targeting and disrupting the fungal cell wall. It belongs to a class of antifungal drugs known as echinocandins. Here’s how Caspofungin Acetate works:

  • Fungal Cell Wall Synthesis:
    Fungi, including Candida and Aspergillus species, have a rigid and protective outer layer called the cell wall. The cell wall is essential for their survival and structural integrity.
  • Inhibition of β1,3DGlucan Synthesis:
    Caspofungin specifically inhibits the synthesis of a key component of the fungal cell wall called beta1,3Dglucan. Beta1,3Dglucan is crucial for providing structural support and stability to the fungal cell wall.
  • Weakening of Fungal Cell Wall:
    When Caspofungin is administered, it interferes with the enzyme (1,3betaDglucan synthase) responsible for building beta1,3Dglucan. This interference disrupts the formation and integrity of the fungal cell wall.
  • Cell Wall Damage and Cell Lysis:
    With the cell wall weakened or incomplete, the fungal cells become structurally compromised. They are unable to maintain their shape and integrity.
  • Cell Lysis and Fungal Death:
    As a result, the fungal cells become susceptible to osmotic stress and eventually rupture or lyse. This leads to the death of the fungal cells.
  • Specificity for Fungi:
    Importantly, Caspofungin Acetate’s mechanism of action is highly specific to fungi and does not affect human cells. Human cells do not have a beta1,3Dglucan cell wall component, making Caspofungin a targeted and lowtoxicity antifungal therapy.

By disrupting the synthesis of the fungal cell wall, Caspofungin Acetate for Injection effectively weakens and destroys the fungal cells. This targeted action makes it a valuable tool in the treatment of invasive fungal infections caused by organisms like Candida and Aspergillus species. It is particularly useful in patients with compromised immune systems or those with serious underlying medical conditions where fungal infections can be lifethreatening.

Benefits of Caspofungin Acetate for Injection:

  • Effective Treatment: Caspofungin Acetate for Injection is highly effective in treating invasive fungal infections caused by Candida and Aspergillus species. It is often used when other antifungal medications may not be suitable due to resistance or safety concerns.
  • Broad Spectrum: It has a broad spectrum of activity against various Candida and Aspergillus species, making it a versatile choice for fungal infections.
  • Low Toxicity: Caspofungin has low toxicity to human cells because it specifically targets the fungal cell wall. This specificity reduces the risk of adverse effects on the patient.
  • Specific Mechanism of Action: Its mechanism of action, targeting beta-1,3-D-glucan synthesis, is specific to fungi and does not affect human cells, making it a highly targeted antifungal therapy.
  • Intravenous Administration: Caspofungin is administered intravenously, ensuring rapid and effective delivery in critical care settings.
  • Treatment of Resistant Infections: It is valuable for the treatment of fungal infections that are resistant to other antifungal medications.
  • Well-Tolerated: Caspofungin is generally well-tolerated by most patients, with fewer side effects compared to some other antifungal medications.

Side Effects of Caspofungin Acetate for Injection:

  • Infusion-Related Reactions: Some patients may experience infusion-related reactions, such as fever, chills, headache, and flushing. These reactions are typically mild and can be managed by slowing down the infusion rate.
  • Gastrointestinal Symptoms: Nausea, vomiting, and diarrhea are possible side effects but are less common.
  • Liver Enzyme Elevation: Caspofungin can lead to elevated liver enzymes in some individuals. Healthcare providers may monitor liver function during treatment.
  • Skin Reactions: Skin reactions, including rash and itching, can occur in some cases.
  • Abnormal Laboratory Values: There may be changes in laboratory values, such as alterations in blood counts, which healthcare providers monitor.
  • Hypersensitivity: In rare cases, individuals may experience hypersensitivity reactions, including anaphylaxis.
  • Electrolyte Imbalances: In some cases, electrolyte imbalances, particularly hypokalemia (low potassium levels), may occur.

It’s important to note that while Caspofungin is generally well-tolerated, the decision to use this medication is made by healthcare providers based on the specific fungal infection, the patient’s medical history, and potential risks and benefits. Fungal infections can be serious, and Caspofungin plays a crucial role in their treatment, especially in patients with compromised immune systems or life-threatening conditions. Any concerns or side effects should be discussed with healthcare professionals during the course of treatment.

Frequently Asked Questions About Caspofungin Acetate for Injection:

Certainly, here are some frequently asked questions (FAQs) about Caspofungin Acetate for Injection:

  1. What is Caspofungin Acetate for Injection used to treat?

Caspofungin Acetate for Injection is primarily used to treat invasive fungal infections caused by Candida and Aspergillus species. These infections can affect various organs and systems in the body and are often seen in individuals with compromised immune systems.

  1. How is Caspofungin Acetate for Injection administered?

It is administered as an intravenous (IV) infusion in a hospital or clinical setting. The dosage and duration of treatment depend on the specific fungal infection and the patient’s response.

  1. Are there any contraindications for using Caspofungin Acetate?

Caspofungin Acetate should be used with caution or avoided in individuals with hypersensitivity to the drug or its components. It may also interact with certain medications, so a thorough review of a patient’s medication history is essential.

  1. Is Caspofungin Acetate safe for use during pregnancy and breastfeeding?

The use of Caspofungin Acetate during pregnancy or breastfeeding should be discussed with a healthcare provider. The potential benefits and risks should be carefully considered.

  1. What should I do if I experience infusionrelated reactions during Caspofungin treatment?

Infusionrelated reactions, such as fever, chills, and headache, are possible but usually mild. Healthcare providers may adjust the infusion rate or provide medications to manage these reactions. It’s important to report any unusual symptoms to your healthcare team.

  1. Can Caspofungin Acetate be used as a prophylactic (preventive) treatment for fungal infections?

It is primarily used for the treatment of established fungal infections rather than as a prophylactic measure. However, in certain highrisk situations, such as bone marrow transplants, it may be used prophylactically.

  1. Is it necessary to monitor liver function during Caspofungin treatment?

Healthcare providers may monitor liver function, including liver enzyme levels, during Caspofungin treatment, as elevated liver enzymes can occur in some individuals.

  1. How long does Caspofungin treatment typically last?

The duration of treatment varies depending on the specific fungal infection and the patient’s response. Healthcare providers will determine the appropriate length of therapy.

  1. Can Caspofungin Acetate interact with other medications?

Yes, Caspofungin can interact with certain medications, so it’s important to inform your healthcare provider about all the medications you are taking.

  1. Can Caspofungin be used in pediatric patients?

Caspofungin Acetate is approved for use in pediatric patients, but the dosage is adjusted based on the child’s age and weight.

Patients should maintain open communication with their healthcare providers, ask questions, and seek clarification regarding Caspofungin Acetate for Injection treatment to ensure safe and effective management of fungal infections.

As Caspofungin Acetate for Injection Exporters; We can cater to export business queries from the following geographies. We are exporting our Caspofungin Acetate for Injection product in the Following Countries-

Russia and CIS Countries: Azerbaijan, Armenia, Belarus, Georgia, Kazakhstan, Kyrgyzstan, Moldova, Russia, Tajikistan, Turkmenistan, Uzbekistan and Ukraine

GCC/ Middle East Countries: Saudi Arabia, Yemen, Oman, Bahrain, UAE, Lebanon, Jordan, and Iraq.

African Countries: Nigeria, Tanzania, Sudan, Zambia, Benin, Angola, Liberia

Southeast Asia: Cambodia, Indonesia, Laos, Malaysia, Myanmar, Philippines, Singapore, Thailand, Vietnam, Brunei Darussalam

Other Asian Countries: Nepal, Myanmar, Malaysia, Cambodia, Bhutan, Sri Lanka, Mauritius

Caspofungin Acetate for Injection Regulatory Documents:

  • Certificate of Analysis (COA)
  • Method of Analysis (MOA)
  • Stability Data (Accelerated stability / Long-term stability / Zone 4b)
  • CTD Dossier / ACTD Dossiers / eCTD Dossiers
  • Certificate of Pharmaceuticals Product (COPP)
  • Free Sale Certificate (FSC)
Contact the most reliable manufacturer of Caspofungin Acetate for Injection, Taj Pharmaceuticals Limited, to get bulk quantities at a reasonable price.

To Place Orders:

Direct line: +91 8448 444 095 / WhatsApp +91 74 0000 9975 / 74 0000 9976
E-Mail: info@tajpharma.com 
Toll free: 1-800-222-434 / Toll free: 1-800-222-825
General EPA BX: +91 22 2637 4592 / +91 22 2637 4593