GENERIC NAME OF THE MEDICINAL PRODUCT:

A. Captopril Tablets 12.5mg
B. Captopril Tablets 25mg
C. Captopril Tablets 50mg
D. Captopril Tablets 100mg

QUALITATIVE AND QUANTITATIVE COMPOSITION:

A. Captopril Tablets 12.5mg
Each uncoated tablet contains:
Captopril USP……………12.5mg
Excipients…………………. q.s.

B. Captopril Tablets 25mg
Each uncoated tablet contains:
Captopril USP…………………...25mg
Excipients………………………...q.s.


C. Captopril Tablets 50mg
Each uncoated tablet contains:
Captopril USP…………………50mg
Excipients……………………......q.s.

D. Captopril Tablets 100mg
Each uncoated tablet contains:
Captopril USP…………………...100mg
Excipients………………………...q.s.

THERAPEUTIC INDICATIONS:

Hypertension: The management of mild to moderate hypertension. In severe hypertension it should be used where standard therapy is ineffective or inappropriate.
Congestive heart failure: Captopril is indicated for the treatment of congestive heart failure. The drug should be used together with diuretics and, when appropriate, digitalis and beta-blockers.

CAUTION & WARNING:

CAUTION: Read enclosed leaflet before use.
*Improve survival after a heart attack.
SWALLOW WHOLE DO NOT CHEW OR CRUSH.
WARNING: To be sold by retail on the prescription of a Registered Medical Practitioner only.
WARNING: Captopril can cause severe, sudden swelling of your face, arms, legs, lips, tongue, throat, and intestines.
Tell your doctor right away if you have swelling or have stomach pain.
KEEP MEDICINE OUT OF REACH OF CHILDREN.

STORAGE & DOSAGE:

Storage: Do not store above 25°C.
Store in the original package in order to protect from moisture.
Dosage: As directed by the Physician.
Attach dispensing label as per end country.

Captopril Tablets 25mg Technical Specification:

Product Name:Captopril Tablets 25mg
Brand Name:CAPOTAJ
Strength:12.5mg, 25mg, 50mg, 100mg
Dosage Form:Tablets (uncoated)
Route of Administration:Via oral route
Packing:30s, 90s, 100s, 500s
Pack Insert/Leaflet:PIL (Patient Information Leaflet), SmPC (Summary Product Characteristics).
Regulatory Documents:COA, MOA, COPP, FSC, Stability Studies, GMP, CTD Dossier
Therapeutic use:Anti-hypertensive, Cardiology, Cardiovascular System.
Indication: Captopril is used to treat high blood pressure (hypertension).
Storage:Do not store above 25°C. Store in the original package in order to protect from moisture.

GENERIC NAME OF THE MEDICINAL PRODUCT:

  • Captopril Tablets 25mg

QUALITATIVE AND QUANTITATIVE COMPOSITION:

  • Captopril Tablets 25mg
    Each uncoated tablet contains:
    Captopril USP……………25mg
    Excipients…………………. q.s.

THERAPEUTIC INDICATIONS:

Hypertension: The management of mild to moderate hypertension. In severe hypertension it should be used where standard therapy is ineffective or inappropriate.
Congestive heart failure: Captopril is indicated for the treatment of congestive heart failure. The drug should be used together with diuretics and, when appropriate, digitalis and beta-blockers.

CAUTION & WARNING:

CAUTION:Read enclosed leaflet before use.
Improve survival after a heart attack.
SWALLOW WHOLE DO NOT CHEW OR CRUSH.
Warning: To be sold by retail on the prescription of a Registered Medical Practitioner only.
Captopril can cause severe, sudden swelling of your face, arms, legs, lips, tongue, throat, and intestines.
Tell your doctor right away if you have swelling or have stomach pain.
Keep medicine out of reach of children.

STORAGE & DOSAGE:

Storage: Do not store above 25°C. Store in the original package in order to protect from moisture.

Dosage: As directed by the Physician.
Attach dispensing label as per end country.

Why Taj Pharmaceuticals?

Captopril Tablets, Taj Pharma sets the gold standard. With a legacy of pharmaceutical excellence, we’ve earned trust through unwavering commitment to quality and patient satisfaction. Our Captopril Tablets are meticulously manufactured, meeting the highest industry standards for efficacy and safety. At Taj Pharma, accessibility and affordability are paramount. We believe essential medications should be within everyone’s reach. Our Captopril Tablets exemplify this ethos, ensuring you receive top-tier treatment without financial strain. What sets us apart is our dedication to your well-being. Taj Pharma understands the significance of effective medications in your health journey. We prioritize your safety and provide premium Captopril Tablets that support your path to better health.

Choose Taj Pharma for your Captopril medication needs, and experience pharmaceutical excellence. Your health deserves nothing less than Taj Pharma’s unwavering commitment to quality, affordability, and care.

What is Captopril Tablets and its use?

Captopril Tablets are a medication used to treat a variety of cardiovascular conditions, primarily hypertension (high blood pressure) and heart-related conditions. Captopril is classified as an angiotensin-converting enzyme (ACE) inhibitor, and it works by relaxing blood vessels, reducing blood pressure, and improving the overall functioning of the heart. Here’s an overview of the primary uses of Captopril Tablets:

  • Hypertension (High Blood Pressure): Captopril is commonly prescribed to manage high blood pressure. By inhibiting the action of ACE, it reduces the production of angiotensin II, a hormone that narrows blood vessels, causing blood pressure to rise. With blood vessels relaxed, blood can flow more easily, leading to a reduction in blood pressure.
  • Heart Failure: Captopril is used in the treatment of heart failure, a condition where the heart is unable to pump blood effectively. It helps by reducing the workload on the heart and improving its pumping ability, which can alleviate symptoms and improve the patient’s quality of life.
  • Post-Heart Attack: In some cases, Captopril may be prescribed after a heart attack to help prevent further heart-related complications. It can reduce strain on the heart and improve its recovery.
  • Kidney Disorders: Captopril can also be used to manage certain kidney disorders, particularly in individuals with diabetic nephropathy (kidney damage caused by diabetes). It helps protect the kidneys by reducing the pressure within the kidney’s blood vessels.
  • Diabetic Patients: Captopril may be prescribed to diabetic patients with high blood pressure or kidney problems, as it can have specific benefits for this patient population.

Captopril Tablets are typically taken orally, and the dosage and frequency are determined by a healthcare provider based on the patient’s specific condition and response to treatment. It’s important to take this medication as directed and attend regular follow-up appointments to monitor its effectiveness and address any potential side effects.

How Does Captopril Tablets Work?

Captopril Tablets work by inhibiting the action of an enzyme called angiotensin-converting enzyme (ACE). This enzyme plays a crucial role in regulating blood pressure and fluid balance in the body. Here’s how Captopril works:

  • Renin-Angiotensin System (RAS): The renin-angiotensin system is a hormonal system that helps regulate blood pressure and fluid balance. One of its key components is angiotensin II, a hormone that constricts blood vessels, leading to an increase in blood pressure.
  • ACE Inhibition: Captopril is classified as an ACE inhibitor. It works by blocking the activity of the ACE enzyme. This inhibition prevents the conversion of angiotensin I (an inactive form) to angiotensin II (the active form).
  • Vasodilation: By inhibiting ACE, Captopril reduces the levels of angiotensin II in the body. As a result, blood vessels relax and dilate (vasodilation), which leads to a decrease in blood pressure. This effect is particularly important in conditions where blood vessels are constricted, such as in hypertension.
  • Reduction in Aldosterone: Another consequence of ACE inhibition is a decrease in the production of aldosterone, a hormone that causes the retention of sodium and water. By reducing aldosterone levels, Captopril helps to decrease fluid volume in the bloodstream, which further contributes to lowering blood pressure.
  • Improvement of Cardiac Function: In heart failure, where the heart’s pumping ability is compromised, Captopril helps by reducing the resistance the heart has to pump against. This improves the heart’s efficiency and overall function.
  • Protection of Kidney Function: Captopril can also benefit individuals with certain kidney disorders. By reducing pressure in the kidney’s blood vessels, it helps protect against further kidney damage.

Overall, Captopril’s mechanism of action helps to regulate blood pressure, improve cardiac function, and protect vital organs like the kidneys. It’s an important medication in the management of hypertension, heart failure, and certain kidney conditions. However, it’s important to take Captopril as prescribed by a healthcare provider, as it is a potent medication with specific dosing instructions. Regular follow-up appointments are also crucial to monitor its effectiveness and address any potential side effects.

Benefits of Captopril Tablets:

  • Blood Pressure Management: The primary benefit of Captopril Tablets is their effectiveness in lowering high blood pressure (hypertension). By relaxing blood vessels, Captopril helps reduce blood pressure, which can lower the risk of heart disease, stroke, and other cardiovascular complications.
  • Heart Failure Management: Captopril is also beneficial in the management of heart failure. It improves the heart’s pumping ability, reduces the workload on the heart, and alleviates symptoms such as shortness of breath and fatigue.
  • Post-Heart Attack Care: In some cases, Captopril may be prescribed after a heart attack to reduce the strain on the heart and help prevent further heart-related complications.
  • Kidney Protection: Captopril can protect the kidneys in individuals with certain kidney disorders, particularly those with diabetic nephropathy (kidney damage caused by diabetes). It helps by reducing pressure within the kidney’s blood vessels.
  • Diabetic Patients: Captopril may be prescribed to diabetic patients with high blood pressure or kidney problems, as it can have specific benefits for this patient population.

Side Effects of Captopril Tablets:

  • Cough: A persistent dry cough is a well-known side effect of ACE inhibitors like Captopril. If this occurs, inform your healthcare provider, as they may need to switch you to a different medication.
  • Low Blood Pressure: Captopril can lead to low blood pressure (hypotension), especially when standing up suddenly. This can cause dizziness or fainting.
  • Elevated Blood Potassium: In some cases, Captopril can lead to an increase in blood potassium levels (hyperkalemia), which can be harmful. Regular monitoring is important.
  • Kidney Function Changes: Captopril can affect kidney function, particularly in individuals with pre-existing kidney disease. Your healthcare provider will monitor kidney function while you are on this medication.
  • Elevated Blood Urea Nitrogen (BUN) and Serum Creatinine: These are markers of kidney function and can be elevated in some individuals taking Captopril.
  • Rash: Skin rashes or itching can occur as a side effect in some cases.
  • Changes in Taste: Some people may experience a metallic or salty taste while taking Captopril.
  • Digestive Symptoms: Nausea, vomiting, and diarrhea are less common side effects.

Frequently asked questions (FAQs) about Captopril Tablets:

  1. What is Captopril and how does it work?

Captopril is a medication classified as an angiotensinconverting enzyme (ACE) inhibitor. It works by blocking the action of an enzyme called ACE, which helps relax blood vessels and lower blood pressure.

  1. What conditions are Captopril Tablets used to treat?

Captopril Tablets are primarily used to treat hypertension (high blood pressure) and heartrelated conditions, including heart failure. It may also be prescribed for certain kidney disorders.

  1. How should I take Captopril Tablets?

Captopril is usually taken orally, typically one to two times a day, with or without food. It’s important to follow your healthcare provider’s instructions and not to adjust the dosage without consulting them.

  1. Can Captopril Tablets be taken with other medications?

Captopril can interact with certain medications, including potassium supplements, diuretics, and nonsteroidal antiinflammatory drugs (NSAIDs). It’s important to inform your healthcare provider about all the medications and supplements you are taking.

  1. What should I do if I miss a dose of Captopril?

If you miss a dose, take it as soon as you remember. However, if it’s almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

  1. Are there any common side effects of Captopril Tablets?

Common side effects may include cough, low blood pressure, elevated blood potassium levels, changes in kidney function, rash, and changes in taste.

  1. Can Captopril be used during pregnancy or while breastfeeding?

Captopril is not recommended during pregnancy, especially in the second and third trimesters, as it can harm the developing fetus. It should not be used while breastfeeding, as it may pass into breast milk and harm the nursing infant.

  1. How long will I need to take Captopril Tablets?

The duration of Captopril treatment will depend on your specific medical condition. It’s important to continue taking it as prescribed by your healthcare provider, even if you feel well.

  1. Can Captopril cause allergic reactions?

While rare, some individuals may experience allergic reactions to Captopril. Seek immediate medical attention if you experience symptoms like rash, itching, swelling, severe dizziness, or difficulty breathing.

  1. How does Captopril affect kidney function?

Captopril can affect kidney function, particularly in individuals with preexisting kidney disease. Your healthcare provider will monitor kidney function while you are on this medication.

As Captopril Tablets Exporters; We can cater to export business queries from the following geographies. We are exporting our Captopril Tablets product in the Following Countries-

Russia and CIS Countries: Azerbaijan, Armenia, Belarus, Georgia, Kazakhstan, Kyrgyzstan, Moldova, Russia, Tajikistan, Turkmenistan, Uzbekistan and Ukraine

GCC/ Middle East Countries: Saudi Arabia, Yemen, Oman, Bahrain, UAE, Lebanon, Jordan, and Iraq.

African Countries: Nigeria, Tanzania, Sudan, Zambia, Benin, Angola, Liberia

Southeast Asia: Cambodia, Indonesia, Laos, Malaysia, Myanmar, Philippines, Singapore, Thailand, Vietnam, Brunei Darussalam

Other Asian Countries: Nepal, Myanmar, Malaysia, Cambodia, Bhutan, Sri Lanka, Mauritius

Captopril Tablets Regulatory Documents:

  • Certificate of Analysis (COA)
  • Method of Analysis (MOA)
  • Stability Data (Accelerated stability / Long-term stability / Zone 4b)
  • CTD Dossier / ACTD Dossiers / eCTD Dossiers
  • Certificate of Pharmaceuticals Product (COPP)
  • Free Sale Certificate (FSC)
Contact the most reliable manufacturer of Captopril Tablets, Taj Pharmaceuticals Limited, to get bulk quantities at a reasonable price.

To Place Orders:

Direct line: +91 8448 444 095 / WhatsApp +91 74 0000 9975 / 74 0000 9976
E-Mail: info@tajpharma.com 
Toll free: 1-800-222-434 / Toll free: 1-800-222-825
General EPA BX: +91 22 2637 4592 / +91 22 2637 4593
Fax No: +91 22 2634 1274