Benzyl Penicillin Injection is an antibiotic used to treat a variety of bacterial infections. It is effective in infections of the throat, ear, nasal sinuses, respiratory tract, skin and soft tissue, and sexually transmitted diseases like syphilis.

Benzyl Penicillin Injection is also used to prevent some infections such as Rheumatic fever and infection of the heart valves (bacterial endocarditis) in people with pre-existing heart disease. It is a penicillin-type of antibiotic, which mainly fights and stops the growth of the gram-positive type of bacteria. It is given as a drip (intravenous infusion) or as an injection directly into a vein or a muscle under the supervision of a healthcare professional. This medicine should be consumed regularly at evenly spaced intervals as per the schedule prescribed by your doctor. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping the medicine too early may lead to the infection returning or worsening. The total duration of treatment and precise dosage will be decided by your doctor, depending on the type of infection that you have and how well you respond to the medication.

Before taking this medicine, inform your doctor if you are allergic to penicillin or any penicillin-type of medicine. Rash, allergic reactions or pain, swelling, and redness at the site of injection may be seen as side effects in some patients. These side effects are temporary and usually resolve quickly. Consult your doctor if any of these side effects persist or if your condition worsens. This medicine is generally regarded as safe to use during pregnancy if used under a doctor’s supervision.

USES OF Benzyl Penicillin Injection

  • Bacterial infections
  • Syphilis
  • Prevention of Rheumatic fever

BENEFITS OF Benzyl Penicillin Injection

In Bacterial infections

Benzyl Penicillin Injection is an antibiotic medicine which can be used to treat many different infections caused by bacteria. It works by stopping the growth of the bacteria causing the infection. This medicine is given by a doctor or a nurse and should not be self-administered. It usually makes you feel better quite quickly. You must continue the treatment as prescribed even when you feel better, to make sure that all bacteria are killed and do not become resistant.

In Syphilis

Syphilis is a bacterial infection usually spread by sexual contact. The disease starts as a painless sore particularly on your genitals, rectum or mouth. If diagnosed in early stages, syphilis can be treated with the use of Benzyl Penicillin Injection, which is an antibiotic that kills the infection causing bacteria and also stops progression of the disease. It is given only by a doctor or nurse into a muscle. Follow the doctor’s instructions carefully to get maximum benefit.

In Prevention of Rheumatic fever

Rheumatic fever is an inflammatory disease caused by the bacteria streptococcus, that results usually die to inadequately treated throat infections or scarlet fever caused by the same microorganisms. Benzyl Penicillin Injection effectively relieves symptoms, controls inflammation and prevents the disease from returning. If you are allergic to penicillin, tell your doctor before taking it, so you can be treated with some other alternate medicine. If you are using it for the first time, let your doctor know if you notice any signs of allergy such as rashes, swelling or any other bothersome side effect.

SIDE EFFECTS OF Benzyl Penicillin Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you are worried about them.

Common side effects of Benzyl Penicillin Injection

  • Rash
  • Allergic reaction
  • Injection site reactions (pain, swelling, redness)

HOW TO USE Benzyl Penicillin Injection

It is given as a drip (intravenous infusion) or as an injection directly into a vein or a muscle under the supervision of a healthcare professional. Your doctor or nurse will give you this medicine. Kindly do not self administer.

HOW Benzyl Penicillin Injection works

Benzyl Penicillin Injection is an antibiotic. It kills bacteria by preventing them from forming the bacterial protective covering (cell wall) which is needed for them to survive.




Consuming alcohol with Benzyl Penicillin Injection does not cause any harmful side effects.


Benzyl Penicillin Injection Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Breast feeding

Benzyl Penicillin Injection is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.


Benzyl Penicillin Injection does not usually affect your ability to drive.


Benzyl Penicillin Injection should be used with caution in patients with kidney disease. Dose adjustment of Benzyl Penicillin Injection may be needed. Please consult your doctor.


Benzyl Penicillin Injection should be used with caution in patients with liver disease. Dose adjustment of Benzyl Penicillin Injection may be needed. Please consult your doctor.

WHAT IF YOU FORGET TO TAKE Benzyl Penicillin Injection?

If you miss a dose of Benzyl Penicillin Injection, consult your doctor.

Alternate brands

For informational purposes only. Consult a doctor before taking any medicines.
No alternate brands found for this medicine


  • It is given by an injection into a vein or muscle, or via a drip into a vein.
  • Finish the prescribed course, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.
  • Inform your doctor immediately if you develop an itchy rash, swelling of the face, throat or tongue or breathing difficulties while taking this medicine.


Q. What should I discuss with my doctor before receiving Benzyl Penicillin Injection?

Before taking Benzyl Penicillin Injection, you should tell your doctor if you have ever had an allergic reaction to Benzyl Penicillin Injection or any similar medicine. Inform the doctor if you have any type of allergy, asthma or breathing problems, heart disease or kidney disease. Let your doctor know about all the medicines that you may be taking as they may affect or be affected by Benzyl Penicillin Injection. Pregnant or breastfeeding mothers should also seek their doctor’s advice before taking Benzyl Penicillin Injection.

Q. Why does Benzyl Penicillin Injection shot hurt so much?

Benzyl Penicillin Injection is injected deeply into the muscle, usually into the butt muscle, using a lot of fluid to inject it. Moreover, it is injected slowly which makes it even more painful.

Q. How is Benzyl Penicillin Injection given?

Benzyl Penicillin Injection must be injected slowly and deeply into a muscle of the buttock or hip. Do not inject this medicine near or into an artery, vein, or nerve as it could lead to some serious side effects.

Q. The solution looks discolored. Can I still use Benzyl Penicillin Injection?

No. You should not use Benzyl Penicillin Injection if the medicine has changed colors or has particles in it. The discolored solution may be contaminated and may not be as effective as it is expected to be. Also, it may cause additional side effects. So, it is better that you discard the solution and go for another vial.

Q. I feel better now. Can I stop taking Benzyl Penicillin Injection?

No. Make sure to receive all doses your doctor has prescribed, even if you feel better. This is because your symptoms may have improved but chances are that the infection is still present in your body. Skipping doses can increase the risk of developing an infection that is resistant to medication. So, continue taking Benzyl Penicillin Injection as prescribed. After you have finished all the doses, your doctor may advise you on some tests to make sure your infection has completely cleared up.

Q. Does Benzyl Penicillin Injection treat the flu?

No. Benzyl Penicillin Injection does not treat a viral infection such as the flu or a common cold.

Q. Can Benzyl Penicillin Injection cause an allergic reaction?

Yes. Benzyl Penicillin Injection may cause an allergic reaction, although it is rare. Get emergency medical help if you have any of the signs of an allergic reaction, such as hives; difficulty breathing; swelling of your face, lips, tongue, or throat.


  1. Chambers HF, Deck DH. Beta-Lactam and Other Cell Wall- & Membrane-Active Antibiotics. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 774.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1080-81.
  3. ScienceDirect. Penicillin G/Benzylpenicillin. [Accessed 28 Mar. 2019] (online) Available from:
  4. Penicillin G/Benzylpenicillin. New York NY: Pfizer Inc; Oct. 2015. [Accessed 29 Mar. 2019] (online) Available from:
  5. U.S. National Library of Medicine. Penicillin G/Benzylpenicillin. [Accessed 29 Mar. 2019] (online) Available from:

Benzyl Penicillin injection is a medicine that is used for the treatment of Bacterial Infections Of Wound, Bacterial Infections Of Blood, Bacterial Infections Of Bones, Bacterial Infections Of Pus Filled Skin, Bacterial Infections Of Nose, Bacterial Infections Of Throat and other conditions.Benzyl Penicillin injection contains Penicillin G as an active ingredient.

Benzyl Penicillin injection works by killing the bacteria by interrupting the bacterial cell wall formation.

Detailed information related to Benzyl Penicillin injection’s uses, composition, dosage, side effects and reviews is listed below.

Benzyl Penicillin injection Uses

Benzyl Penicillin injection is used for the treatment, control, prevention, & improvement of the following diseases, conditions and symptoms:

  • Bacterial Infections Of Wound
  • Bacterial Infections Of Blood
  • Bacterial Infections Of Bones
  • Bacterial Infections Of Pus Filled Skin
  • Bacterial Infections Of Nose
  • Bacterial Infections Of Throat

Benzyl Penicillin injection Working, Mechanism of Action and Pharmacology

Benzyl Penicillin injection improves the patient’s condition by performing the following functions:

Killing the bacteria by interrupting the bacterial cell wall formation.

Benzyl Penicillin injection – Composition and Active Ingredients

  • Benzyl Penicillin injection is composed of the following active ingredients (salts) -Penicillin G
  • Please note that this medicine may be available in various strengths for each active ingredient listed above.

Benzyl Penicillin injection – Side-effects

The following is a list of possible side effects that may occur from all constituting ingredients of Benzyl Penicillin injection. This is not a comprehensive list. These side effects are possible but do not always occur. Some of the side effects may be rare but serious. Consult your doctor if you observe any of the following side effects, especially if they do not go away.

  • Swelling Of The Tissues In Kidney
  • Serum Sickness
  • Rare Severe Allergic Reactions
  • Abnormal Decrease In White Blood Cell Count
  • Convulsions
  • Chills

Benzyl Penicillin injection – Precautions & How to Use

Before using this drug, inform your doctor about your current list of medications, over the counter products (e.g. vitamins, herbal supplements, etc.), allergies, pre-existing diseases, and current health conditions (e.g. pregnancy, upcoming surgery, etc.). Some health conditions may make you more susceptible to the side effects of the drug. Take as directed by your doctor or follow the direction printed on the product insert. Dosage is based on your condition. Tell your doctor if your condition persists or worsens. Important counseling points are listed below.

  • Avoid using penicillin if allergic to it
  • Should be used carefully in patients with Allergic reactions
  • Take caution while taking penicillin in case of pregnancy and breastfeeding

Additional Information-The most common markets for this product include the following countries. Please inquire with us if your country or region is not listed:

Asia: Afghanistan, Israel, Jordan, Pakistan, Russia, Saudi Arabia, Singapore, Syria, Philippines, Turkey, Turkmenistan, Uzbekistan, Yemen, Vietnam, Indonesia, Malaysia, Iran, Tajikistan, etc.

Africa: South Africa, Uganda, Nigeria, Ghana, Kenya, Mauritius, Botswana, Egypt, Ethiopia, Libya, Sudan, Congo, Gambia, Ivory Coast, etc.

North & South America:USA, Canada, Panama, Trinidad and Tobago, Costa Rica, Puerto Rico, Dominican Republic, Argentina, Guatemala, Guyana, Peru, Bolivia, Venezuela , Brazil, Bahamas, Ecuador, etc .

Europe: Austria, Azerbaijan, Belarus, Belgium, Cyprus, Czech Republic, Denmark, France, Georgia, Germany, Hungary, Ireland, Iceland, Netherlands, Norway, Poland, Spain, Sweden, Switzerland, Ukraine, United Kingdom (UK), Latvia, etc.

OCEANIA: Australia, New Zealand, Fiji, etc.

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