GENERIC NAME OF MEDICINAL PRODUCT:

(A) Benzyl Penicillin Sodium for Injection B.P. 0.8 MIU

QUALITATIVE AND QUANTITATIVE COMPOSITION:

A. Benzyl Penicillin Sodium for Injection B.P. 0.8 MIU
a) Each vial contains:
Benzyl Penicillin Sodium BP
(As sodium) ………………………800,000IU
b) Sterile Water for Injection BP ….…………… 20ml

THERAPEUTIC INDICATION:

Benzyl Penicillin is a local anaesthetic and antibiotic combination for intramuscular injection to treat a variety of bacterial infections while reducing pain from a deep intramuscular injection. Benzylpenicillin is an injectable antibiotic.

DIRECTION OF USE:

The powder to be reconstituted with 20ml of Sterile Water for Injections BP.
FOR IM USE ONLY
The prepared solution should be use immediately after preparation. The prepared solution should be used only, if it is clear.

CAUTION & WARNING:

CAUTION: If any foreign particle is visible in the vial after dissolving the contents, please do not use the solution.
FLIP-OFF SEAL IS PROVIDED FOR TAMPER EVIDENCE.
Reconstituted solution should be use immediately after preparation.
Any unused reconstitution portion must be discarded.
Read enclosed leaflet before use.
Not to be infuse directly:
Dilute the preparation with compatible intravenous solution prior to administration.
WARNING: Not to be sold by retail without the prescription of Registered Medical Practitioner.
“Penicillin Sensitivity Test Essentail”

STORAGE & DOSAGE:

STORAGE: Store below 25°C. Protect from Light. Do not freeze.
Keep medicine out of reach of children.
DOSAGE: As directed by Physician.

Benzyl Penicillin Sodium for Injection B.P. 0.8 MIU Technical Specification:

Product Name:Benzyl Penicillin Sodium for Injection B.P.
jBrand Name:Generics
Strength:0.8 MIU
Dosage Form:Dry Powder Injection (Sterile)
Packing:Vial + WFI in Tray
Route of Administration:For I.M. use
Pack Insert/Leaflet:PIL (Patient Information Leaflet), SmPC (Summary Product Characteristics)
Regulatory Documents:COA, MOA, COPP, FSC, Stability Studies, GMP, CTD Dossier
Therapeutic use:β-lactam Antibiotic, Anti-bacterial & Penicillin
Indication: Procaine benzylpenicillin is a local anaesthetic and antibiotic combination for intramuscular injection to treat a variety of bacterial infections while reducing pain from a deep intramuscular injection. Benzylpenicillin is an injectable antibiotic.
Storage:Store below 25°C. Protect from Light. Do not freeze.

GENERIC NAME OF MEDICINAL PRODUCT:

  • Benzyl Penicillin Sodium for Injection B.P. 0.8 MIU

QUALITATIVE AND QUANTITATIVE COMPOSITION:

  1. Benzyl Penicillin Sodium for Injection B.P. 0.8 MIU
    a) Each vial contains:
    Benzyl Penicillin Sodium BP
    (As sodium) ………………………800,000IU
    b) Sterile Water for Injection BP ….…………… 20ml

THERAPEUTIC INDICATION:

Benzyl Penicillin is a local anesthetic and antibiotic combination for intramuscular injection to treat a variety of bacterial infections while reducing pain from a deep intramuscular injection. Benzylpenicillin is an injectable antibiotic.

DIRECTION OF USE:

The powder to be reconstituted with 20ml of Sterile Water for Injections BP.

FOR IM USE ONLY

The prepared solution should be use immediately after preparation. The prepared solution should be used only, if it is clear.

CAUTION & Warning:

CAUTION:  If any foreign particle is visible in the vial after dissolving the contents, please do not use the solution.

FLIP-OFF SEAL IS PROVIDED FOR TAMPER EVIDENCE.

Reconstituted solution should be use immediately after preparation.

Any unused reconstitution portion must be discarded.

Read enclosed leaflet before use.

Not to be infuse directly:
Dilute the preparation with compatible intravenous solution prior to administration.

WARNING: Not to be sold by retail without the prescription of Registered Medical Practitioner.
“Penicillin Sensitivity Test Essential”

STORAGE & DOSAGE:

STORAGE:  Store below 25°C. Protect from Light. Do not freeze.

Keep medicine out of reach of children.

DOSAGE:  As directed by Physician.

Why Taj Pharmaceuticals?

Taj Pharma is your trusted source for Benzyl Penicillin Sodium for Injection BP, offering a blend of expertise, quality, and dedication to healthcare. Our commitment to pharmaceutical excellence is reflected in every vial of Benzyl Penicillin Sodium we produce. With a heritage of pharmaceutical innovation and a global presence, Taj Pharma is recognized for consistently delivering reliable antibiotics. Our stringent quality control measures ensure that each batch of Benzyl Penicillin Sodium meets the highest industry standards, providing healthcare professionals and patients with confidence in its efficacy and safety. At Taj Pharma, we understand the critical importance of antibiotics like Benzyl Penicillin Sodium in combating bacterial infections. Our state-of-the-art manufacturing facilities and quality assurance processes guarantee a consistent supply of this essential medication. We take pride in contributing to the well-being and health of communities worldwide. when it comes to Benzyl Penicillin Sodium for Injection BP, Taj Pharma stands as the epitome of pharmaceutical excellence, offering quality, availability, and a steadfast commitment to advancing healthcare. Partner with us to experience the difference in healthcare solutions that Taj Pharma brings to the forefront.

What is Benzyl Penicillin Sodium for Injection BP and its use?

Benzyl Penicillin Sodium for Injection BP, often referred to simply as Penicillin G Sodium, is a medication belonging to the class of antibiotics known as penicillins. It is used to treat a variety of bacterial infections. Here’s some key information about Benzyl Penicillin Sodium and its uses:

  • Composition:
    Benzyl Penicillin Sodium for Injection BP contains the active ingredient benzylpenicillin (penicillin G sodium), which is a narrow spectrum antibiotic.
  • Mechanism of Action:
    Benzyl Penicillin Sodium works by inhibiting the growth and replication of bacteria. It interferes with the formation of bacterial cell walls, leading to the weakening and eventual rupture of the bacterial cell, ultimately causing the death of the bacteria.
  • Medical Uses:
    Benzyl Penicillin Sodium is effective against a wide range of bacterial infections caused by susceptible organisms. Some common medical uses include:
    Respiratory Infections: It can be used to treat conditions such as pneumonia, bronchitis, and tonsillitis.
    Skin and Soft Tissue Infections: It is effective against skin infections like cellulitis, impetigo, and abscesses.
    Stretococcal Infections: Benzyl Penicillin Sodium is often used to treat streptococcal infections, including strep throat and scarlet fever.
    Syphilis: It is one of the antibiotics used to treat syphilis, a sexually transmitted infection.
    Meningitis: In some cases, it may be used to treat bacterial meningitis.
    Endocarditis Prophylaxis: It is sometimes given to individuals with certain heart conditions before dental or surgical procedures to prevent endocarditis.
  • Administration:
    Benzyl Penicillin Sodium for Injection BP is typically administered by healthcare professionals, often in a hospital or clinical setting. It can be given intravenously (IV) or intramuscularly (IM), depending on the specific infection and patient’s condition.
  • Precautions:
    Prior to using this medication, healthcare providers need to consider factors such as the patient’s medical history, allergies, and the susceptibility of the bacteria causing the infection. Allergic reactions to penicillin can be severe, so it’s crucial to identify patients with penicillin allergies.
  • Duration of Treatment:
    The duration of treatment with Benzyl Penicillin Sodium varies depending on the type and severity of the infection. It’s important for patients to complete the entire prescribed course of antibiotics to ensure the infection is fully treated.

As with any antibiotic, the use of Benzyl Penicillin Sodium for Injection BP should be guided by a healthcare professional based on the specific infection and individual patient factors. It is important to follow the prescribed dosage and treatment plan to effectively manage bacterial infections and minimize the risk of antibiotic resistance.

How does Benzyl Penicillin Sodium for Injection BP work?

Benzyl Penicillin Sodium for Injection BP, also known as Penicillin G Sodium, is an antibiotic that works by interfering with the growth and replication of bacteria. Its mechanism of action is based on the following principles:

  • Cell Wall Inhibition: Bacterial cells are surrounded by a protective outer layer known as the cell wall. This cell wall is essential for maintaining the structural integrity of the bacterium.
  • Penicillin-Binding Proteins (PBPs): Inside the bacterial cell wall, there are enzymes known as penicillin-binding proteins (PBPs). These PBPs play a crucial role in building and maintaining the bacterial cell wall.
  • Inhibition of PBPs: Benzyl Penicillin Sodium belongs to a class of antibiotics known as beta-lactam antibiotics, which includes penicillins and cephalosporins. These antibiotics have a molecular structure called a beta-lactam ring, which is similar in shape to a component of the bacterial cell wall.
  • Binding to PBPs: When Benzyl Penicillin Sodium is administered, it circulates in the bloodstream and reaches the site of infection. There, it binds to the PBPs on the bacterial cell wall.
  • Inhibition of Cross-Linking: By binding to the PBPs, Benzyl Penicillin Sodium interferes with the enzymes’ ability to cross-link the components of the bacterial cell wall. This cross-linking is crucial for the stability of the cell wall.
  • Weakening of the Cell Wall: As a result of the inhibition of cross-linking, the bacterial cell wall becomes weakened and less able to withstand the internal pressure of the bacterial cell.
  • Cell Lysis: With a weakened cell wall, the bacterial cell becomes susceptible to rupture or lysis. The internal pressure builds up, causing the bacterial cell to burst and release its contents, including cellular components and genetic material.
  • Bacterial Death: The rupture of bacterial cells and the release of their contents lead to bacterial death. This process effectively eliminates the infection and stops the spread of the bacteria.

It’s important to note that Benzyl Penicillin Sodium has a relatively narrow spectrum of activity, meaning it is effective against a specific range of bacteria, primarily gram-positive bacteria. It is less effective against gram-negative bacteria due to differences in the structure of their cell walls.

Benefits of Benzyl Penicillin Sodium for Injection BP:

  • Effective Antibacterial Treatment: Benzyl Penicillin Sodium is highly effective against a wide range of gram-positive bacteria. It is a valuable tool for treating various bacterial infections caused by susceptible organisms.
  • Historical Significance: Penicillin G, the active ingredient in Benzyl Penicillin Sodium, was the first antibiotic discovered and revolutionized the treatment of bacterial infections. It has played a pivotal role in modern medicine.
  • Versatile Use: This antibiotic is used to treat a variety of infections, including respiratory infections, skin and soft tissue infections, streptococcal infections, syphilis, and more.
  • Prophylactic Use: Benzyl Penicillin Sodium is sometimes used prophylactically in specific medical procedures, such as dental work or surgery, to prevent bacterial infections in susceptible individuals.

Side Effects and Risks of Benzyl Penicillin Sodium for Injection BP:

  • Allergic Reactions: Allergic reactions to penicillin antibiotics can range from mild skin rashes to severe anaphylaxis, which is a potentially life-threatening condition. Allergic reactions can occur even in individuals who have never had a previous allergic response to penicillin.
  • Gastrointestinal Disturbances: Common side effects may include nausea, vomiting, diarrhea, and abdominal pain.
  • Skin Reactions: Some individuals may experience skin reactions like rashes, itching, or hives.
  • Superinfections: Prolonged or repeated use of antibiotics like Benzyl Penicillin Sodium can lead to the development of superinfections, where new infections occur due to the overgrowth of non-susceptible bacteria or fungi.
  • Kidney Damage: In rare cases, high doses of Benzyl Penicillin Sodium can potentially cause kidney damage, particularly when administered for extended periods.
  • Neurological Effects: High doses or rapid intravenous administration of this antibiotic may lead to neurological symptoms such as seizures.
  • Resistance: The overuse or misuse of antibiotics can contribute to the development of antibiotic-resistant bacteria, which can be a significant public health concern.
  • Interactions: Benzyl Penicillin Sodium can interact with other medications, so it’s essential to inform your healthcare provider about any other drugs you are taking.

It’s important to note that while Benzyl Penicillin Sodium is highly effective against susceptible bacteria, it should only be used when prescribed by a healthcare professional who has considered the specific bacterial infection, its susceptibility to penicillin, and the patient’s medical history. Any potential side effects or allergic reactions should be promptly reported to a healthcare provider. Additionally, individuals with known penicillin allergies should avoid this medication and inform their healthcare providers of their allergy.

Frequently asked questions about Benzyl Penicillin Sodium for Injection BP

Benzyl penicillin sodium, also known as penicillin G sodium, is a widely used antibiotic medication. Below are some frequently asked questions about Benzylpenicillin Sodium for Injection BP:

  1. What is Benzyl penicillin Sodium for Injection BP?

Benzyl penicillin Sodium for Injection BP is a sterile powder or solution that contains the antibiotic benzylpenicillin sodium. It is used to treat a variety of bacterial infections.

  1. How does Benzyl penicillin Sodium work?

Benzyl penicillin sodium works by inhibiting the growth and replication of bacteria. It does this by interfering with the formation of bacterial cell walls, which are essential for their survival.

  1. What types of infections is Benzyl penicillin Sodium used to treat?

Benzyl penicillin sodium is effective against a wide range of bacterial infections, including respiratory tract infections, skin and soft tissue infections, syphilis, and more serious infections like endocarditis and meningitis.

  1. Is it available in different forms?

Yes, Benzyl penicillin Sodium is available in various forms, including powder for reconstitution into an injectable solution, which can be administered intravenously or intramuscularly.

  1. How is Benzyl penicillin Sodium administered?

The specific administration route and dosage will depend on the type and severity of the infection. Healthcare professionals typically administer it intravenously or intramuscularly.

  1. Are there any precautions or contraindications for its use?

Benzyl penicillin sodium should not be used in individuals with a known allergy to penicillin or beta lactam antibiotics. It should be used with caution in patients with a history of hypersensitivity reactions.

  1. What are the common side effects?

Common side effects may include pain or redness at the injection site, allergic reactions, diarrhea, and nausea. Severe side effects like anaphylaxis are rare but can occur.

  1. Is it safe for use during pregnancy and breastfeeding?

Benzyl penicillin sodium is generally considered safe for use during pregnancy and breastfeeding when the benefits outweigh the potential risks. However, it’s essential to consult with a healthcare provider.

  1. Can it be used in pediatric patients?

Yes, Benzyl penicillin Sodium can be used in pediatric patients, but the dosage will be adjusted based on the child’s weight and specific medical condition.

  1. Is a prescription required to obtain Benzyl penicillin Sodium for Injection BP?

Yes, a prescription from a licensed healthcare provider is required to obtain and administer Benzyl penicillin Sodium for Injection BP.

  1. Are there any drug interactions to be aware of?

It’s important to inform your healthcare provider of all medications and supplements you are taking as certain drugs may interact with Benzyl penicillin Sodium, potentially reducing its effectiveness or increasing the risk of side effects.

  1. How should Benzyl penicillin Sodium be stored?

It should be stored in a cool, dry place, protected from light, and according to the manufacturer’s instructions. Always check the expiration date before use.

As Benzyl Penicillin Sodium for Injection BP Exporters; We can cater to export business queries from the following geographies. We are exporting our Benzyl Penicillin Sodium for Injection BP product in the Following Countries-

Russia and CIS Countries: Azerbaijan, Armenia, Belarus, Georgia, Kazakhstan, Kyrgyzstan, Moldova, Russia, Tajikistan, Turkmenistan, Uzbekistan and Ukraine

GCC/ Middle East Countries: Saudi Arabia, Yemen, Oman, Bahrain, UAE, Lebanon, Jordan, and Iraq.

African Countries: Nigeria, Tanzania, Sudan, Zambia, Benin, Angola, Liberia

Southeast Asia: Cambodia, Indonesia, Laos, Malaysia, Myanmar, Philippines, Singapore, Thailand, Vietnam, Brunei Darussalam

Other Asian Countries: Nepal, Myanmar, Malaysia, Cambodia, Bhutan, Sri Lanka, Mauritius

Benzyl Penicillin Sodium for Injection BP Regulatory Documents:

  • Certificate of Analysis (COA)
  • Method of Analysis (MOA)
  • Stability Data (Accelerated stability / Long-term stability / Zone 4b)
  • CTD Dossier / ACTD Dossiers / eCTD Dossiers
  • Certificate of Pharmaceuticals Product (COPP)
  • Free Sale Certificate (FSC)
Contact the most reliable manufacturer of Benzyl Penicillin Sodium for Injection BP, Taj Pharmaceuticals Limited, to get bulk quantities at a reasonable price.

To Place Orders:

Direct line: +91 8448 444 095 / WhatsApp +91 74 0000 9975 / 74 0000 9976
E-Mail: info@tajpharma.com 
Toll free: 1-800-222-434 / Toll free: 1-800-222-825
General EPA BX: +91 22 2637 4592 / +91 22 2637 4593
Fax No: +91 22 2634 1274