Pemetrexed for Injection 500mg (Actoforan) – Leading Manufacturer, Supplier & Exporter in India

Taj Pharmaceuticals Ltd, based in Vapi, Gujarat, India, is a globally recognized manufacturer, supplier, and exporter of Pemetrexed for Injection 500mg (Actoforan). We are committed to delivering premium quality oncology medicines that meet stringent WHO-GMP and international regulatory standards, ensuring patient safety, efficacy, and affordability. Our wide distribution network covers PAN India markets, including Mumbai, Maharashtra, and extends globally to Africa, the Middle East, and LATAM regions.


About Pemetrexed for Injection 500mg (Actoforan)

Pemetrexed Injection 500mg is an essential chemotherapy medication belonging to the class of antifolate antineoplastic agents. It is a prescription-only medicine used to treat:

  • Non-Small Cell Lung Cancer (NSCLC)
  • Malignant Pleural Mesothelioma

The drug works by blocking folate-dependent enzymes that are crucial for the synthesis of DNA and RNA, effectively preventing the growth and multiplication of cancer cells.

  • Generic Name: Pemetrexed for Injection
  • Brand Name: Actoforan
  • Strength: 500mg per vial
  • Form: Lyophilized powder for IV infusion
  • Route of Administration: Intravenous (IV)

Therapeutic Indications of Pemetrexed Injection

  1. Non-Small Cell Lung Cancer (NSCLC):
    • Used as a first-line therapy with cisplatin.
    • Recommended for maintenance treatment in patients whose cancer has not progressed after prior chemotherapy.
  2. Malignant Pleural Mesothelioma:
    • Administered in combination with cisplatin for patients unsuitable for surgical intervention.

Mechanism of Action – How Pemetrexed Works

Pemetrexed is a multi-targeted antifolate drug that inhibits:

  • Thymidylate Synthase (TS)
  • Dihydrofolate Reductase (DHFR)
  • Glycinamide Ribonucleotide Formyltransferase (GARFT)

These enzymes are essential for DNA and RNA building blocks. By inhibiting them, Pemetrexed starves cancer cells of necessary components, thereby halting their replication and spread.


Why Choose Taj Pharmaceuticals as Your Pemetrexed Manufacturer?

1. WHO-GMP Certified Facilities

Our production plants in Vapi, Gujarat, comply with Good Manufacturing Practices, ensuring global-standard quality.

2. Strict Quality Control

Each batch undergoes multi-level quality testing for safety, stability, and efficacy.

3. Global Reach

We are a trusted exporter of Pemetrexed Injection to PAN India, Africa, Middle East, CIS, LATAM, and Asia-Pacific markets.

4. Affordable Oncology Medicines

Our pricing strategy ensures cost-effective chemotherapy drugs, making treatments accessible worldwide.

5. Regulatory Compliance

We adhere to national and international health regulations, ensuring global approvals for exports.


Dosage & Administration of Pemetrexed for Injection

  • Recommended Dose: 500mg administered as an IV infusion over 10 minutes.
  • Combination Therapy: Most effective when combined with cisplatin.
  • Supplements: Patients must take folic acid and vitamin B12 to reduce toxicity risks.
  • Precautions:
    • Avoid use in pregnancy; contraception is required.
    • Should only be administered by oncology specialists.

Possible Side Effects of Pemetrexed Injection

Like most chemotherapy drugs, Pemetrexed Injection may cause side effects:

  • Common Side Effects:
    • Nausea, vomiting, loss of appetite
    • Fatigue and weakness
    • Diarrhea or constipation
    • Rash, sore throat, and mouth ulcers
    • Hair loss (alopecia)
    • Low blood counts (anemia, neutropenia, thrombocytopenia)
  • Serious Side Effects:
    • Severe infections with fever and chills
    • Breathing difficulty or chest pain
    • Allergic reactions such as swelling and severe rash
    • Neuropathy (tingling, numbness)

Patients must seek immediate medical help if severe side effects occur.


Technical Specifications of Pemetrexed Injection 500mg

  • Product Name: Pemetrexed for Injection (Actoforan)
  • Strength: 500mg
  • Form: Lyophilized powder for IV infusion
  • Route of Administration: Intravenous
  • Packing: Single-use vial with sterile diluent (market dependent)
  • Storage: Below 25°C, protect from light, keep out of children’s reach
  • Leaflet/Insert: Includes dosage instructions, precautions, and safety guidelines
  • Regulatory Compliance: WHO-GMP, ISO-certified

Global Supply Network

Taj Pharmaceuticals Ltd has established itself as a reliable oncology medicine exporter:

  • India (PAN India): Mumbai, Delhi, Chennai, Hyderabad, and Ahmedabad.
  • Africa: Nigeria, Ghana, Kenya, South Africa, Tanzania.
  • Middle East: UAE, Saudi Arabia, Kuwait, Oman, Qatar.
  • LATAM: Brazil, Mexico, Argentina.
  • CIS Nations: Russia, Ukraine, Kazakhstan.

Pemetrexed Injection Best Price in Mumbai, Maharashtra

We provide Pemetrexed Injection 500mg at competitive prices in Mumbai, Maharashtra, and across India. Our PAN India distribution channels ensure timely delivery to hospitals, oncology clinics, and government tenders.


Pemetrexed Injection PCD Pharma Franchise

Taj Pharma also offers PCD Pharma Franchise opportunities for oncology products, including Pemetrexed Injection. Our partners benefit from:

  • Monopoly rights in their region.
  • High-quality promotional support.
  • Affordable price structure.
  • Assured supply chain management.

Trusted Oncology Partner

With decades of expertise, Taj Pharmaceuticals Ltd continues to be a leading manufacturer and exporter of chemotherapy medicines, particularly Pemetrexed for Injection 500mg (Actoforan). Our mission is to ensure affordable cancer treatment worldwide while upholding the highest standards of quality and compliance.


📌 Contact Us for Pemetrexed Injection Supply

📧 Email: info@tajpharma.com
🌍 Website: www.tajpharma.com
📞 Call/WhatsApp: +91 84484 44095
Tel: +91 – 22 – 2637 4592 / 2637 4593
📠 Fax: +91 – 22 – 2634 1274


Pemetrexed for Injection 500mg (Actoforan) is a lifesaving chemotherapy drug, and Taj Pharmaceuticals Ltd stands as the #1 manufacturer, supplier, and exporter in India. With our global reach, WHO-GMP certified facilities, and commitment to affordable cancer care, we remain the most trusted name for Pemetrexed Injection supply across India and worldwide.