New evidence supports inverse association between cancer and Alzheimer
Among patients with a history of cancer, risk of Alzheimer disease (AD) might be lower: a study published in JAMA Network Open showed that elderly cancer patients had modestly higher memory function and slower memory decline both before and after their diagnosis compared with similarly aged individuals who remained cancer free. This result suggests that the risk of cancer may be lower among patients with AD, and that cancer survivors may have a lower risk of developing AD than people who did not develop any tumour.
The inverse association between cancer and AD or other neurodegenerative diseases has been already described extensively in the literature, however evidence remains scarce on the long-term cognitive trajectories, as Monica Ospina-Romero, MD, from the department of epidemiology and biostatistics at University of California, San Francisco, and colleagues wrote.
To compare long-term memory trajectories before and after cancer with those memory trajectories of individuals cancer free, researchers conducted a population-based cohort study which included over 14.500 U.S. adults from the Health and Retirement Study. Biennially, they assessed participants from 1998 to 2014 to determine composite memory score and compare the rates of memory change. Of 14,583 participants included in the study, followed for 11.5 in average, 2,250 had a cancer diagnosis while 12,333 had not. The rate of memory decline in the decade before a cancer diagnosis was 10.5% which was slower than memory decline in similarly aged cancer-free individuals. In addition, a new cancer diagnosis was associated with a short-term decrease in memory compared with memory before the diagnosis.
Analysis revealed moreover that average memory function immediately before cancer diagnosis was slightly higher for individuals diagnosed at age 75 years than memory function among cancer-free adults of the same age. The results also showed a slower rate of memory decline after a cancer diagnosis compared with individuals without cancer.
“These findings support the possibility of a common pathologic process working in opposite directions in cancer and AD,” the researchers wrote. “Identification of a potential association between carcinogenesis and neurodegeneration may open a new avenue in research for prevention and treatment of AD.”
About – Taj Oncology
Taj Oncology’s vision is to become a world class player in oncology through excellence in innovation, discovery of new manufacturing processes / drug delivery mechanisms and consistently high quality of production.
We commenced operations in 1994 with the inauguration of our ultra-modern facility for the production of generics and formulations for oncology and other therapeutic applications. We are one of the pioneers in India in lyophilization.
We identified, very early, the need for achieving self – sufficiency in formulations as well as in Active Pharmaceutical Ingredients (APIs) , and our achievements reflect this focus. We launched our (APIs) in year 1994 & now have to our credit a number of new manufacturing processes & drug delivery mechanisms.
We have a manufacturing plant located at Tarapur, Thane in Maharashtra State. This facility meets the current Good Manufacturing Practices norms as laid down by the World Health Organization.
Our marketing spans domestic and overseas operations. With a network across the Indian sub-continent and market penetration in several countries across four continents, we are on our way to meeting our target of reaching out to cancer patients, worldwide.
Taj Pharmaceuticals, is a generics pharmaceuticals company with product range exceeding 4600 compositions under all therapeutic categories
Taj Pharmaceuticals Limited manufactures and distributes medicines. The company’s products include prescription solutions, lifesaving drugs, anti-cancer drugs, veterinary products, consumer brands, and CNS drugs. It focuses on medicines of anemia, anxiety disorders, cancer/oncology, ear infections, heart failure, hepatitis, HIV/AIDS, influenza, non-Hodgkin’s lymphoma, obesity, osteoporosis, Parkinson’s disease, pneumonia, transplantation, and common diseases. Taj Pharmaceuticals India Business is headquartered in Mumbai, India.
Taj Pharmaceuticals is the global leader in generics and one of the India’s top ten pharmaceutical companies. Taj Pharma India play a leading role in therapeutic areas such as cancer, virology and transplantation. The combined strengths of Taj Pharma generics and pharmaceuticals businesses, coupled with expertise in the emerging genetic sciences, equip us to develop integrated healthcare solutions and therapeutic approaches tailored to individual patients’ needs. Taj Pharmaceutical’s products and services address the entire healthcare spectrum, from screening for genetic risk factors, to preventing, diagnosing and treating disease, and monitoring the treatment response.
Taj Pharma India delivers a unique contribution to better healthcare. Taj Pharma India aim to reduce suffering and improve health and quality of life of people all around the world. At Taj Pharmaceuticals, Taj Pharma India have pursued this mission with patience, dedication, imagination and skill, for over a century. Taj Pharma vision is to develop targeted medicines and diagnostic tools that combine to offer patients, physicians and payers better, safer, more cost-effective healthcare.
Once again, welcome to Taj Pharmaceuticals, a great company that is translating a great vision into reality – We Innovate Generics Healthcare.
Taj Pharmaceuticals Limited is committed to earning the trust of doctors, patients and customers every day. Taj Pharma colleagues worldwide believe that trust is not easily granted, and that is the reason Taj Pharma India focus each day on becoming a champion for Taj Pharma stakeholders.
During the past ten years, Taj Pharmaceuticals Group has been building a new kind of health care company. Throughout Taj Pharma Group (India), there’s a desire to build long-term relationships with Taj Pharma stakeholders based on mutual confidence. This is evident in many ways. Taj Pharma scientists are earning trust through the discovery and development of innovative, science-based medicines and services that improve the health and overall well-being of people around the world. Taj Pharma sales professionals, marketing teams, colleagues working at Taj Pharma plants and others throughout the organization at all levels of responsibility take each day as a fresh opportunity to earn trust.
All of this takes hard work, sharp execution, integrity and transparency on the part of Taj Pharmaceuticals Group colleagues. Taj Pharma global team is working to sustain and expand innovative new treatments. Taj Pharma India’re determined to do Taj Pharma part to increase access to better health care for all people. And, Taj Pharma India is focused on becoming the best in three key strategic areas: people, products and processes.
Taj Pharma India’re beginning to see the results of Taj Pharma efforts, but believe the best is yet to come. The test of being a true champion is to never give up and to passionately strive for even better outcomes. From Taj Pharma perspective as a health care company, that means helping people around the world live better and live longer.The product range includes major generic drugs under therapeutic category such as anti-cancer drugs, CNS drugs; Key category of products includes generic medicines for anemia, anxiety disorders, cancer/oncology, ear infections, heart failure, hepatitis, HIV/AIDS, influenza, non-Hodgkin’s lymphoma, obesity, osteoporosis, Parkinson’s disease, pneumonia, transplantation and common diseases.